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http://hdl.handle.net/1942/39413
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DC Field | Value | Language |
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dc.contributor.author | ROBIJNS, Jolien | - |
dc.contributor.author | LODEWIJCKX, Joy | - |
dc.contributor.author | CLAES, Marithe | - |
dc.contributor.author | Tuts, Laura | - |
dc.contributor.author | Lenaerts, Melissa | - |
dc.contributor.author | Wessels, Tim | - |
dc.contributor.author | Requilé, Annelies | - |
dc.contributor.author | Luyten, Daisy | - |
dc.contributor.author | Verheezen, Jolanda | - |
dc.contributor.author | Joosens, Eric | - |
dc.contributor.author | MEBIS, Jeroen | - |
dc.date.accessioned | 2023-02-13T16:22:25Z | - |
dc.date.available | 2023-02-13T16:22:25Z | - |
dc.date.issued | 2023 | - |
dc.date.submitted | 2023-02-11T08:51:04Z | - |
dc.identifier.citation | European Journal of Oncology Nursing, (Art N° 102278) | - |
dc.identifier.issn | 1462-3889 | - |
dc.identifier.uri | http://hdl.handle.net/1942/39413 | - |
dc.description.abstract | Purpose Evaluate the efficacy of a novel skincare product for the management of chemotherapy-related dermatological toxicities. Methods A monocentric, prospective, interventional, open-label, pretest-posttest, single-group study with cancer patients receiving chemotherapy (n = 100) was set up. All enrolled patients applied the emollient daily to their face and body for three weeks. The severity of the skin reactions was evaluated by a researcher using the Common Terminology Criteria for Adverse Events (CTCAE) v5.0 at baseline and end of the trial. Patient-reported outcomes (PROs) included the frequency and severity of skin symptoms (Numerical rating scale, NRS), quality of life (QoL; Skindex-16 and Dermatology Life Quality Index), Patient Benefit Index (PBI), and treatment satisfaction. PROs were collected at baseline, weekly, and at the end of the trial. Results According to the CTCAE and NRS, the novel emollient significantly improved the severity and frequency of xerosis and pruritus (Ps ≤ .001). A significant reduction in the NRS score for frequency of erythema was measured (p < .001). The frequency and severity of burning and pain did not change. Regarding the patients’ QoL, no beneficial effect of the skin care product was measurable. 44% of the patients experienced at least one patient-relevant treatment benefit. 87% of the patients were satisfied with the emollient and would recommend it. Conclusions This study shows that the novel emollient significantly reduced chemotherapy-induced skin toxicity, more specifically xerosis and pruritus without hampering patient's QoL. Future research is needed to make definite conclusions using a study design including a control group and a long-term follow-up. | - |
dc.description.sponsorship | Limburgs Kankerfonds | - |
dc.language.iso | en | - |
dc.publisher | - | |
dc.subject.other | Cancer | - |
dc.subject.other | Chemotherapy | - |
dc.subject.other | Emollient | - |
dc.subject.other | Oncology | - |
dc.subject.other | Skin care | - |
dc.subject.other | Skin toxicity | - |
dc.title | Evaluation of a novel skin care product for the management of chemotherapy– related dermatologic toxicities: A quasi-experimental study | - |
dc.type | Journal Contribution | - |
dc.identifier.volume | 63 | - |
local.bibliographicCitation.jcat | A1 | - |
local.publisher.place | THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
local.bibliographicCitation.artnr | 102278 | - |
dc.identifier.doi | 10.1016/j.ejon.2023.102278 | - |
dc.identifier.isi | 000955268700001 | - |
dc.identifier.eissn | 1532-2122 | - |
local.provider.type | CrossRef | - |
local.uhasselt.international | yes | - |
item.fulltext | With Fulltext | - |
item.accessRights | Restricted Access | - |
item.contributor | ROBIJNS, Jolien | - |
item.contributor | LODEWIJCKX, Joy | - |
item.contributor | CLAES, Marithe | - |
item.contributor | Tuts, Laura | - |
item.contributor | Lenaerts, Melissa | - |
item.contributor | Wessels, Tim | - |
item.contributor | Requilé, Annelies | - |
item.contributor | Luyten, Daisy | - |
item.contributor | Verheezen, Jolanda | - |
item.contributor | Joosens, Eric | - |
item.contributor | MEBIS, Jeroen | - |
item.fullcitation | ROBIJNS, Jolien; LODEWIJCKX, Joy; CLAES, Marithe; Tuts, Laura; Lenaerts, Melissa; Wessels, Tim; Requilé, Annelies; Luyten, Daisy; Verheezen, Jolanda; Joosens, Eric & MEBIS, Jeroen (2023) Evaluation of a novel skin care product for the management of chemotherapy– related dermatologic toxicities: A quasi-experimental study. In: European Journal of Oncology Nursing, (Art N° 102278). | - |
crisitem.journal.issn | 1462-3889 | - |
crisitem.journal.eissn | 1532-2122 | - |
Appears in Collections: | Research publications |
Files in This Item:
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1-s2.0-S1462388923000121-main.pdf Restricted Access | Early view | 1.42 MB | Adobe PDF | View/Open Request a copy |
1-s2.0-S1462388923000121-main.pdf Restricted Access | Published version | 2.41 MB | Adobe PDF | View/Open Request a copy |
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