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| | Issue Date | Title | Contributor(s) | Type | Cat. |
| 1 | 2024 | Does Central Statistical Monitoring Improve Data Quality? An Analysis of 1,111 Sites in 159 Clinical Trials | de Viron, Sylviane; Trotta, Laura; Steijn, William; Young, Steve; BUYSE, Marc | Journal Contribution | A1 |
| 2 | 2023 | On Enhancing Clinical Trial Data Sharing | BUYSE, Marc | Journal Contribution | A2 |
| 3 | 2023 | HIGHLIGHTING THE MULTIDIMENSIONAL BENEFITS OF A DRUG USING GENERALIZED PAIRWISE COMPARISONS | Chiem, J. C.; Saad, E.; De Backer, M.; Salvaggio, S.; Kosta, S.; Barre, E.; DELTUVAITE-THOMAS, Vaiva; VERBEECK, Johan; BUYSE, Marc | Journal Contribution | M |
| 4 | 2023 | INCLUDING PATIENT RELEVANT ENDPOINTS (QUALITY OF LIFE) IN MULTICOMPONENT ENDPOINTS WITH GENERALIZED PAIRWISE COMPARISONS | VERBEECK, Johan; De, Backer M.; Barre, E.; Salvaggio, S.; DELTUVAITE-THOMAS, Vaiva; Chiem, J. C.; Kosta, S.; BUYSE, Marc | Journal Contribution | M |
| 5 | 2023 | Trial Design for Cancer Immunotherapy: A Methodological Toolkit | Saad, Everardo D.; Coart, Elisabeth; DELTUVAITE-THOMAS, Vaiva; GARCIA BARRADO, Leandro; BURZYKOWSKI, Tomasz; BUYSE, Marc | Journal Contribution | A1 |
| 6 | 2023 | Generalized pairwise comparisons of prioritized outcomes are a powerful and patient-centric analysis of multi-domain scores | DELTUVAITE-THOMAS, Vaiva; De Backer, Mickael; Parker, Samantha; Deneux, Marie; Polgreen, Lynda E.; O'Neill, Cara; Salvaggio, Samuel; BUYSE, Marc | Journal Contribution | A1 |
| 7 | 2023 | Re-Evaluation of Pathologic Complete Response as a Surrogate for Event-Free and Overall Survival in Human Epidermal Growth Factor Receptor 2-Positive, Early Breast Cancer Treated With Neoadjuvant Therapy Including Anti-Human Epidermal Growth Factor Receptor 2 Therapy | Squifflet, Pierre D.; Saad, Everardo; Loibl, Sibylle T.; van Mackelenbergh, Marion; Untch, Michael; Rastogi, Priya; Gianni, Luca; Schneeweiss, Andreas; Conte, Pierfranco; Piccart, Martine; Bonnefoi, Herve; Jackisch, Christian; Nekljudova, Valentina; Tang, Gong; Valagussa, Pinuccia; Neate, Colin; Gelber, Richard; Poncet, Coralie; Heinzmann, Dominik; Denkert, Carsten E.; Geyer Jr, Charles; Cortes, Javier; Guarneri, Valentina; de Azambuja, Evandro; Cameron, David; Ismael, Gustavo; Wolmark, Norman; Cortazar, Patricia; BUYSE, Marc; CTNeoBC Project | Journal Contribution | A1 |
| 8 | 2023 | Individualized Net Benefit estimation and meta-analysis using generalized pairwise comparisons in N-of-1 trials | Giai, Joris; Peron, Julien; Roustit, Matthieu; Cracowski, Jean-Luc; Roy, Pascal; Ozenne, Brice; BUYSE, Marc; Maucort-Boulch, Delphine | Journal Contribution | A1 |
| 9 | 2023 | Disease-free survival as the endpoint in multimodal rectal cancer trials: have we got this right? | Fokas, Emmanouil; Roedel, Claus; Smith, J. Joshua; Garcia-Aguilar, Julio; BUYSE, Marc; Glynne-Jones, Robert | Journal Contribution | A2 |
| 10 | 2023 | Minimization in randomized clinical trials | Coart, Elisabeth; Bamps, Perrine; Quinaux, Emmanuel; Sturbois, Geneviève; Saad, Everardo D; BURZYKOWSKI, Tomasz; BUYSE, Marc | Journal Contribution | A1 |
| 11 | 2023 | Generalized pairwise comparisons for censored data: An overview | DELTUVAITE-THOMAS, Vaiva; VERBEECK, Johan; BURZYKOWSKI, Tomasz; BUYSE, Marc; Tournigand, Christophe; MOLENBERGHS, Geert; THAS, Olivier | Journal Contribution | A1 |
| 12 | 2023 | Generalized Pairwise Comparisons to Assess Treatment Effects: JACC Review Topic of the Week | VERBEECK, Johan; De Backer, Mickael; VERWERFT, Jan; Salvaggio, Samuel; Valgimigli, Marco; VRANCKX, Pascal; BUYSE, Marc; Brunner, Edgar | Journal Contribution | A1 |
| 13 | 2022 | Detection of Fraud in a Clinical Trial Using Unsupervised Statistical Monitoring | de Viron, Sylviane; Trotta, Laura; Schumacher, Helmut; Lomp, Hans-Juergen; Hoppner, Sebastiaan; Young, Steve; BUYSE, Marc | Journal Contribution | A1 |
| 14 | 2022 | Clinical Trial Endpoints in Metastatic Cancer: Using Individual Participant Data to Inform Future Trials Methodology | Goldberg, Richard M.; Adams, Richard; BUYSE, Marc; Eng, Cathy; Grothey, Axel; Andre, Thierry; Sobrero, Alberto F.; Lichtman, Stuart M.; Benson, Al B.; Punt, Cornelis J. A.; Maughan, Tim; BURZYKOWSKI, Tomasz; Sommeijer, Dirkje; Saad, Everardo D.; Shi, Qian; Coart, Elisabeth; Chibaudel, Benoist; Koopman, Miriam; Schmoll, Hans-Joachim; Yoshino, Takayuki; Taieb, Julien; Tebbutt, Niall C.; Zalcberg, John; Tabernero, Josep; Van Cutsem , Eric; Matheson, Alastair; de Gramont, Aimery | Journal Contribution | A1 |
| 15 | 2022 | Surrogacy Beyond Prognosis: The Importance of “Trial-Level” Surrogacy | BUYSE, Marc; Saad, Everardo D.; BURZYKOWSKI, Tomasz; Regan, Meredith M.; Sweeney, Christopher S. | Journal Contribution | A1 |
| 16 | 2022 | On the use of extreme value tail modeling for generalized pairwise comparisons with censored outcomes | De Backer, Mickael; LEGRAND, Catherine; Peron, Julien; Lambert, Alexandre; BUYSE, Marc | Journal Contribution | A1 |
| 17 | 2022 | Does Central Monitoring Lead to Higher Quality? An Analysis of Key Risk Indicator Outcomes | de Viron, Sylviane; Trotta, Laura; Steijn, William; Young, Steve; BUYSE, Marc | Journal Contribution | A1 |
| 18 | 2022 | The case against censoring of progression-free survival in cancer clinical trials - A pandemic shutdown as an illustration | Jamoul, Corinne; Collette, Laurence; Coart, Elisabeth; D'Hollander, Koenraad; BURZYKOWSKI, Tomasz; Saad, Everardo D; BUYSE, Marc | Journal Contribution | A1 |
| 19 | 2022 | Using an interim analysis based exclusively on an early outcome in a randomized clinical trial with a long-term clinical endpoint | Barrado, Leandro Garcia; BURZYKOWSKI, Tomasz; LEGRAND, Catherine; BUYSE, Marc | Journal Contribution | A1 |
| 20 | 2021 | International consensus recommendations on key outcome measures for organ preservation after (chemo)radiotherapy in patients with rectal cancer | Fokas, Emmanouil; Appelt, Ane; Glynne-Jones, Robert; Beets, Geerard; Perez, Rodrigo; Garcia-Aguilar, Julio; Rullier, Eric; Joshua Smith, J.; Marijnen, Corrie; Peters, Femke P.; van der Valk, Maxine; Beets-Tan, Regina; Myint, Arthur S.; Gerard, Jean-Pierre; Bach, Simon P.; Ghadimi, Michael; Hofheinz, Ralf D.; Bujko, Krzysztof; Haustermans, Karin; Minsky, Bruce D.; Ludmir, Ethan; West, Nicholas P.; Gambacorta, Maria A.; Valentini, Vincenzo; BUYSE, Marc; Renehan, Andrew G.; Gilbert, Alexandra; Sebag-Montefiore, David; Roedel, Claus; Gani, Cihan | Journal Contribution | A1 |
| 21 | 2021 | Impact of follow-up on generalized pairwise comparisons for estimating the irinotecan benefit in advanced/metastatic gastric cancer | Chamseddine, AN; Oba, K; BUYSE, Marc; Boku, N; Bouche, O; Satar, T; Auperin, A; PAOLETTI, Xavier | Journal Contribution | A1 |
| 22 | 2021 | Net benefit in the presence of correlated prioritized outcomes using generalized pairwise comparisons: A simulation study | Giai, Joris; Maucort-Boulch, Delphine; Ozenne, Brice; Chiem, Jean-Christophe; BUYSE, Marc; Peron, Julien | Journal Contribution | A1 |
| 23 | 2021 | A new measure of treatment effect in clinical trials involving competing risks based on generalized pairwise comparisons | Cantagallo, Eva; De Backer, Mickael; KICINSKI, Michal; Ozenne, Brice; Collette, Laurence; LEGRAND, Catherine; BUYSE, Marc; Peron, Julien | Journal Contribution | A1 |
| 24 | 2021 | Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID): a factorial, randomised, controlled trial | Declercq , Jozefien; Van Damme, Karel F. A.; De Leeuw, Elisabeth; Maes, Bastiaan; Bosteels, Cedric; Tavernier, Simon J.; De Buyser, Stefanie; Colman, Roos; Hites, Maya; Verschelden, Gil; Fivez, Tom; Moerman , Filip; Demedts, Ingel K.; Dauby, Nicolas; De Schryver, Nicolas; Govaerts , Elke; Vandecasteele, Stefaan J.; Van Laethem, Johan; Anguille, Sebastien; VAN DER HILST, Jeroen; Misset, Benoit; Slabbynck, Hans; Wittebole, Xavier; Lienart, Fabienne; LEGRAND, Catherine; BUYSE, Marc; Stevens, Dieter; Bauters, Fre; Seys, Leen J. M.; Aegerter, Helena; Smole, Ursula; Bosteels, Victor; Hoste , Levi; Naesens, Leslie; Haerynck, Filomeen; Vandekerckhove, Linos; Depuydt, Pieter; van Braeckel, Eva; Rottey, Sylvie; Peene, Isabelle; Van Der Straeten, Catherine; Hulstaert, Frank; Lambrecht, Bart N. | Journal Contribution | A1 |
| 25 | 2021 | The Net Benefit of a treatment should take the correlation between benefits and harms into account | BUYSE, Marc; Saad, Everardo D.; Peron, Julien; Chiem, Jean-Christophe; De Backer, Mickael; Cantagallo, Eva; Ciani, Oriana | Journal Contribution | A1 |
| 26 | 2021 | The International Collaboration for Research methods Development in Oncology (CReDO) workshops: shaping the future of global oncology research | Ranganathan, P; Chinnaswamy, G; Sengar, M; Gadgil, D; Thiagarajan, S; Bhargava, B; Booth, CM; BUYSE, Marc; Chopra, S; Frampton, C; Gopal, S; Grant, N; Krailo, M; Langley, R; Mathur, P; PAOLETTI, Xavier; Parmar, M; Purushotham, A; Pyle, D; Rajaraman, P; Stockler, MR; Sullivan, R; Swaminathan, S; Tannock, I; Trimble, E; Badwe, RA; Pramesh, CS | Journal Contribution | A1 |
| 27 | 2021 | Correcting the bias of the net benefit estimator due to right-censored observations | Peron, Julien; Idlhaj, Maryam; Maucort-Boulch, Delphine; Giai, Joris; Roy, Pascal; Collette, Laurence; BUYSE, Marc; Ozenne, Brice | Journal Contribution | A1 |
| 28 | 2021 | Evaluation of surrogate endpoints | MOLENBERGHS, Geert; SHKEDY, Ziv; BURZYKOWSKI, Tomasz; BUYSE, Marc; ALONSO ABAD, Ariel; VAN DER ELST, Wim | Book Section | B2 |
| 29 | 2020 | Unbiasedness and efficiency of non-parametric and UMVUE estimators of the probabilistic index and related statistics | VERBEECK, Johan; DELTUVAITE-THOMAS, Vaiva; BERCKMOES, Ben; BURZYKOWSKI, Tomasz; AERTS, Marc; THAS, Olivier; BUYSE, Marc; MOLENBERGHS, Geert | Journal Contribution | A1 |
| 30 | 2020 | Progression-free survival (PFS) as a surrogate endpoint for overall survival (OS) in advanced/recurrent gastric cancer (AGC) treatment: Individual-patient-data (IPD) based meta-analysis of randomized trials | Oba, Koji; Paoletto, Xavier; Bang, Yung-Jue; Bouche, Olivier; Ducreux, Michel; Michiels, Stefan; Moehler, MarkusH; Morita, Satoshi; Ohashi, Yasuo; Sakamoto, Junichi; Sasako, Mitsuru; Shitara, Kohei; Van Cutsem, Eric; BUYSE, Marc; BURZYKOWSKI, Tomasz | Journal Contribution | M |
| 31 | 2020 | Commentary on Bamat et al | Saad, Everardo D.; BUYSE, Marc | Journal Contribution | A2 |
| 32 | 2020 | Central statistical monitoring of investigator-led clinical trials in oncology | BUYSE, Marc; Trotta, Laura; Saad, Everardo D.; Sakamoto, Junichi | Journal Contribution | A1 |
| 33 | 2020 | Statistical aspects in adjuvant and neoadjuvant trials for gastrointestinal cancer in 2020: focus on time-to-event endpoints | Saad, Everardo D.; BUYSE, Marc | Journal Contribution | A1 |
| 34 | 2020 | Outcome measures in multimodal rectal cancer trials | Fokas, Emmanouil; Glynne-Jones, Robert; Appelt, Ane; Beets-Tan, Regina; Beets, Geerard; Haustermans, Karin; Marijnen, Corrie; Minsky, Bruce D.; Ludmir, Ethan; Quirke, Phil; Sebag-Montefiore, David; Garcia-Aguilar, Julio; Gambacorta, Maria Antonietta; Valentini, Vincenzo; BUYSE, Marc; Rodel, Claus | Journal Contribution | A1 |
| 35 | 2020 | Statistical Considerations for Trials in Adjuvant Treatment of Colorectal Cancer | Saad, Everardo Delforge; BUYSE, Marc | Journal Contribution | A1 |
| 36 | 2020 | Meta-analytic approach to evaluation of surrogate endpoints | BURZYKOWSKI, Tomasz; BUYSE, Marc; MOLENBERGHS, Geert; ALONSO ABAD, Ariel; VAN DER ELST, Wim; SHKEDY, Ziv | Book Section | B2 |
| 37 | 2020 | Infectious diseases epidemiology, quantitative methodology, and clinical research in the midst of the COVID-19 pandemic: Perspective from a European country | MOLENBERGHS, Geert; BUYSE, Marc; ABRAMS, Steven; HENS, Niel; Beutels, Philippe; FAES, Christel; VERBEKE, Geert; Van Damme, Pierre; Goossens, Herman; NEYENS, Thomas; HERZOG, Sereina; Theeten, Heidi; Pepermans, Koen; Abad, Ariel Alonso; VAN KEILEGOM, Ingrid; Speybroeck, Niko; LEGRAND, Catherine; De Buyser, Stefanie; Hulstaert, Frank | Journal Contribution | A1 |
| 38 | 2019 | Disease-free survival as a surrogate for overall survival in patients with HER2-positive, early breast cancer in trials of adjuvant trastuzumab for up to 1 year: a systematic review and meta-analysis | Saad, Everardo D.; Squifflet, Pierre; BURZYKOWSKI, Tomasz; Quinaux, Emmanuel; Delaloge, Suzette; Mavroudis, Dimitris; Perez, Edith; Piccart-Gebhart, Martine; Schneider, Bryan P.; Slamon, Dennis; Wolmark, Norman; BUYSE, Marc | Journal Contribution | A1 |
| 39 | 2019 | Detection of atypical data in multicenter clinical trials using unsupervised statistical monitoring | Trotta, Laura; Kabeya, Yuusuke; BUYSE, Marc; Doffagne, Erik; Venet, David; Desmet, Lieven; BURZYKOWSKI, Tomasz; Tsuburaya, Akira; Yoshida, Kazuhiro; Miyashita, Yumi; Morita, Satoshi; Sakamoto, Junichi; Praveen, Paurush; Oba, Koji | Journal Contribution | A1 |
| 40 | 2019 | A Poisson approach to the validation of failure time surrogate endpoints in individual patient data meta-analyses | Rotolo, Federico; PAOLETTI, Xavier; BURZYKOWSKI, Tomasz; BUYSE, Marc; Michiels, Stefan | Journal Contribution | A1 |
| 41 | 2019 | Evaluation of Continuous Tumor-Size-Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer | BURZYKOWSKI, Tomasz; Coart, E.; Saad, E.D.; Shi, Q.; Sommeijer, D.W.; Bokemeyer, C.; Díaz-Rubio, E.; Douillard, Jean-Yves; Falcone, A.; Fuchs, C.; Goldberg, R.M.; Hecht, R.; Hoff, P.M.; Hurwitz, H.; Kabbinavar, F.F.; Koopman, M.; Maughan, T.; Punt, C.J.A.; Saltz, L.; Schmoll, Hans-Joachim; Seymour, M.T.; Tebbutt, N.C.; Tournigand, C.; Van Cutsem, E.; de Gramont, A.; Zalcberg, J.R.; BUYSE, Marc | Journal Contribution | A1 |
| 42 | 2019 | Chronological Trends in Progression-Free, Overall, and Post-Progression Survival in First-Line Therapy for Advanced NSCLC | Rutkowski, Jacek; Saad, Everardo D.; BURZYKOWSKI, Tomasz; BUYSE, Marc; Jassem, Jacek | Journal Contribution | A1 |
| 43 | 2019 | Assessing Long-Term Survival Benefits of Immune Checkpoint Inhibitors Using the Net Survival Benefit | Peron, Julien; Lambert, Alexandre; Munier, Stephane; Ozenne, Brice; Giai, Joris; Roy, Pascal; Dalle, Stephane; Machingura, Abigirl; Maucort-Boulch, Delphine; BUYSE, Marc | Journal Contribution | A1 |
| 44 | 2018 | The search for surrogate endpoints for immunotherapy trials | BUYSE, Marc; BURZYKOWSKI, Tomasz; Saad, Everardo D. | Journal Contribution | A2 |
| 45 | 2018 | Understanding and Communicating Measures of Treatment Effect on Survival: Can We Do Better? | Saad, Everardo D.; Zalcberg, John R.; Peron, Julien; Coart, Elisabeth; BURZYKOWSKI, Tomasz; BUYSE, Marc | Journal Contribution | A1 |
| 46 | 2018 | An extension of generalized pairwise comparisons for prioritized outcomes in the presence of censoring | Peron, Julien; BUYSE, Marc; Ozenne, Brice; Roche, Laurent; Roy, Pascal | Journal Contribution | A1 |
| 47 | 2018 | Statistical evaluation of surrogate endpoints in cancer clinical trials | BUYSE, Marc; MOLENBERGHS, Geert; PAOLETTI, Xavier; Oba, K.; ALONSO ABAD, Ariel; VAN DER ELST, Wim; BURZYKOWSKI, Tomasz | Book Section | B2 |
| 48 | 2017 | Applied Surrogate Endpoint Evaluation Methods with SAS and R | ALONSO ABAD, Ariel; BIGIRUMURAME, Theophile; BURZYKOWSKI, Tomasz; BUYSE, Marc; MOLENBERGHS, Geert; MUCHENE, Leacky; PERUALILA, Nolen Joy; SHKEDY, Ziv; VAN DER ELST, Wim | Book | B1 |
| 49 | 2017 | Exploratory analysis of the association of depth of response and survival in patients with metastatic non-small-cell lung cancer treated with a targeted therapy or immunotherapy | Saad, Everardo D.; BUYSE, Marc | Journal Contribution | A2 |
| 50 | 2017 | Evaluation of failure time surrogate endpoints in individual patient data meta-analyses of randomized clinical trials. A poisson approach | Rotolo, Federico; PAOLETTI, Xavier; BURZYKOWSKI, Tomasz; BUYSE, Marc; Michiels, Stefan | Journal Contribution | M |
| 51 | 2017 | Adoption of Pathologic Complete Response as a Surrogate End Point in Neoadjuvant Trials in HER2-Positive Breast Cancer Still an Open Question | BURZYKOWSKI, Tomasz; Saad, Everardo D.; BUYSE, Marc | Journal Contribution | A1 |
| 52 | 2017 | Precision medicine needs randomized clinical trials | Saad, Everardo D.; PAOLETTI, Xavier; BURZYKOWSKI, Tomasz; BUYSE, Marc | Journal Contribution | A1 |
| 53 | 2017 | Progression-Free Survival as a Surrogate for Overall Survival in Clinical Trials of Targeted Therapy in Advanced Solid Tumors | Michiels, Stefan; Saad, Everardo D.; BUYSE, Marc | Journal Contribution | A1 |
| 54 | 2017 | The impact of data errors on the outcome of randomized clinical trials | BUYSE, Marc; Squifflet, Pierre; Coart, Elisabeth; Quinaux, Emmanuel; Punt, Cornelis J. A.; Saad, Everardo D. | Journal Contribution | A1 |
| 55 | 2017 | The potential and perils of observational studies | BUYSE, Marc; Vansteelandt, Stijn | Journal Contribution | A1 |
| 56 | 2017 | Use of the Beta-Binomial Model for Central Statistical Monitoring of Multicenter Clinical Trials | Desmet, Lieven; Venet, David; Doffagne, Erik; Timmermans, Catherine; LEGRAND, Catherine; BURZYKOWSKI, Tomasz; BUYSE, Marc | Journal Contribution | A1 |
| 57 | 2017 | Authors' Reply to Schoenfeld: "Progression-Free Survival as a Surrogate for Overall Survival in Clinical Trials of Targeted Therapy in Advanced Solid Tumors" | Michiels, Stefan; Saad, Everardo D.; BUYSE, Marc | Journal Contribution | A1 |
| 58 | 2017 | Improving public health by improving clinical trial guidelines and their application | Landray, Martin J.; Bax, Jeroen J.; Alliot, Laurence; BUYSE, Marc; Cohen, Adam; Collins, Rory; Hindricks, Gerhard; James, Stefan K.; Lane, Sile; Maggioni, Aldo P.; Meeker-O'Connell, Ann; Olsson, Gunnar; Pocock, Stuart J.; Rawlins, Michael; Sellors, Jonathan; Shinagawa, Kaori; Sipido, Karin R.; Smeeth, Liam; Stephens, Richard; Stewart, Murray W.; Stough, Wendy Gattis; Sweeney, Fergus; Van de Werf, Frans; Woods, Kerrie; Casadei, Barbara | Journal Contribution | A1 |
| 59 | 2016 | Data Sharing - Is the Juice Worth the Squeeze? | Strom, Brian L.; BUYSE, Marc; Hughes, John; Knoppers, Bartha M. | Journal Contribution | A1 |
| 60 | 2016 | Fraud in clinical trials: complex problem, simple solutions? | Sakamoto, Junichi; BUYSE, Marc | Journal Contribution | A2 |
| 61 | 2016 | Progression-free survival as surrogate end point for overall survival in clinical trials of HER2-targeted agents in HER2-positive metastatic breast cancer | Michiels, Stefan; Pugliano, L.; Marguet, S.; Grun, D.; Barinoff, J.; Cameron, D.; Cobleigh, M.; Di Leo, A.; Johnston, S.; Gasparini, G.; Kaufman, B.; Marty, M.; Nekljudova, V.; Paluch-Shimon, S.; Penault-Llorca, F.; Slamon, D.; Vogel, C.; von Minckwitz, G.; BUYSE, Marc; Piccart, M. | Journal Contribution | A1 |
| 62 | 2016 | Statistical monitoring of data quality and consistency in the Stomach Cancer Adjuvant Multi-institutional Trial Group Trial | Timmermans, Catherine; Doffagne, Erik; Venet, David; Desmet, Lieven; LEGRAND, Catherine; BURZYKOWSKI, Tomasz; BUYSE, Marc | Journal Contribution | A1 |
| 63 | 2016 | Statistical evaluation of surrogate endpoints with examples from cancer clinical trials | BUYSE, Marc; MOLENBERGHS, Geert; PAOLETTI, Xavier; Oba, Koji; ALONSO ABAD, Ariel; VAN DER ELST, Wim; BURZYKOWSKI, Tomasz | Journal Contribution | A1 |
| 64 | 2016 | Neoadjuvant as Future for Drug Development in Breast Cancer-Letter | BUYSE, Marc; BURZYKOWSKI, Tomasz; Saad, Everardo D. | Journal Contribution | A1 |
| 65 | 2016 | The Net Chance of a Longer Survival as a Patient-Oriented Measure of Treatment Benefit in Randomized Clinical Trials | Peron, Julien; Roy, Pascal; Ozenne, Brice; Roche, Laurent; BUYSE, Marc | Journal Contribution | A1 |
| 66 | 2016 | Response to the letter to the editor 'Reply to "Statistical controversies in clinical research: end points other than survival are vital for regulatory approval of anticancer agents" by H. K. van Halteren' | Saad, E. D.; BUYSE, Marc | Journal Contribution | A1 |
| 67 | 2016 | Adaptive Randomization of Neratinib in Early Breast Cancer | BUYSE, Marc; Saad, E.; BURZYKOWSKI, Tomasz | Journal Contribution | A1 |
| 68 | 2016 | An Information-Theoretic Approach for the Evaluation of Surrogate Endpoints Based on Causal Inference | ALONSO ABAD, Ariel; VAN DER ELST, Wim; MOLENBERGHS, Geert; BUYSE, Marc; BURZYKOWSKI, Tomasz | Journal Contribution | A1 |
| 69 | 2016 | Statistical controversies in clinical research: end points other than overall survival are vital for regulatory approval of anticancer agents | Saad, E. D.; BUYSE, Marc | Journal Contribution | A1 |
| 70 | 2016 | Neratinib after trastuzumab in patients with HER2-positive breast cancer Reply | Chan, Arlene; BUYSE, Marc; Yao, Bin | Journal Contribution | A1 |
| 71 | 2015 | Event-Free Survival Is a Surrogate for Overall Survival in Patients Treated for Acute Myeloid Leukemia | Schlenk, Richard F.; Doehner, Hartmut; Doehner, Konstanze; Ganser, Arnold; Heuser, Michael; Benner, Axel; BUYSE, Marc; BURZYKOWSKI, Tomasz | Journal Contribution | M |
| 72 | 2015 | Meta-analyses of randomized controlled trials show suboptimal validity of surrogate outcomes for overall survival in advanced colorectal cancer | Ciani, Oriana; BUYSE, Marc; Garside, Ruth; Peters, Jaime; Saad, Everardo D.; Stein, Ken; Taylor, Rod S. | Journal Contribution | A1 |
| 73 | 2015 | On the relationship between the causal-inference and meta-analytic paradigms for the validation of surrogate endpoints | ALONSO ABAD, Ariel; VAN DER ELST, Wim; MOLENBERGHS, Geert; BURZYKOWSKI, Tomasz; BUYSE, Marc | Journal Contribution | A1 |
| 74 | 2015 | Evaluation of treatment efficacy using a Bayesian mixture piecewise linear model of longitudinal biomarkers | Zhao, Lili; Feng, Dai; Neelon, Brian; BUYSE, Marc | Journal Contribution | A1 |
| 75 | 2015 | Biomarker‑based surrogate endpoints | BUYSE, Marc; BURZYKOWSKI, Tomasz; MOLENBERGHS, Geert; ALONSO ABAD, Ariel | Book Section | B2 |
| 76 | 2014 | Implementation Issues in Adaptive Design Trials | Danielson, Linda; Carlier, Jerome; BURZYKOWSKI, Tomasz; BUYSE, Marc | Book Section | B2 |
| 77 | 2014 | Data Sharing, Year 1 - Access to Data from Industry-Sponsored Clinical Trials | Strom, Brian L.; BUYSE, Marc; Hughes, John; Knoppers, Bartha M. | Journal Contribution | A2 |
| 78 | 2014 | Linear mixed-effects models for central statistical monitoring of multicenter clinical trials | Desmet, L.; Venet, D.; Doffagne, E.; Timmermans, C.; BURZYKOWSKI, Tomasz; LEGRAND, Catherine; BUYSE, Marc | Journal Contribution | A1 |
| 79 | 2013 | Review: Clinical Trial Methodology: Surrogate endpoints: when should they be used? | MOLENBERGHS, Geert; ALONSO ABAD, Ariel; VAN DER ELST, Wim; BURZYKOWSKI, Tomasz; BUYSE, Marc | Journal Contribution | A1 |
| 80 | 2013 | Professor Maurice Staquet, MD, MS (1930-2013) In Memoriam | Duez, Nicole; Eeckhoudt, Dominique; Kirkpatrick, Anne; Solbu, Gabriel; Suciu, Stefan; SYLVESTER, Richard; Van Glabbeke, Martine; BUYSE, Marc; Dalesio, Otilia; Renard, Josette; Rotmensz, Nicole | Journal Contribution | M |
| 81 | 2013 | Statistical evaluation of surrogate endpoints in clinical studies | MOLENBERGHS, Geert; ALONSO ABAD, Ariel; VAN DER ELST, Wim; BURZYKOWSKI, Tomasz; BUYSE, Marc | Book Section | B2 |
| 82 | 2013 | Role of chemotherapy for advanced/recurrent gastric cancer: An individual-patient-data meta-analysis | Oba, Koji; PAOLETTI, Xavier; Bang, Yung-Jue; Bleiberg, Harry; BURZYKOWSKI, Tomasz; Fuse, Nozomu; Michiels, Stefan; Morita, Satoshi; Ohashi, Yasuo; Pignon, Jean-Pierre; Rougier, Philippe; Pompidou, Georges; Sakamoto, Junichi; Sargent, Daniel; Sasako, Mitsuru; Shitara, Kohei; Tsuburaya, Akira; Van Cutsem, Eric; BUYSE, Marc | Journal Contribution | A1 |
| 83 | 2013 | Prediction of survival benefits from progression-free survival benefits in advanced non-small-cell lung cancer: evidence from a meta-analysis of 2334 patients from 5 randomised trials | Laporte, Silvy; Squifflet, Pierre; Baroux, Noemie; Fossella, Frank; Georgoulias, Vassilis; Pujol, Jean-Louis; Douillard, Jean-Yves; Kudoh, Shinzohy; Pignon, Jean-Pierre; Quinaux, Emmanuel; BUYSE, Marc | Journal Contribution | A1 |
| 84 | 2013 | Disease-Free Survival as a Surrogate for Overall Survival in Adjuvant Trials of Gastric Cancer: A Meta-Analysis | Oba, Koji; PAOLETTI, Xavier; Alberts, Steven; Bang, Yung-Jue; Benedetti, Jacqueline; Bleiberg, Harry; CATALANO, Paul; Lordick, Florian; Michiels, Stefan; Morita, Satoshi; Ohashi, Yasuo; Pignon, Jean-pierre; Rougier, Philippe; Sasako, Mitsuru; Sakamoto, Junichi; Sargent, Daniel; Shitara, Kohei; Cutsem, Eric Van; BUYSE, Marc; BURZYKOWSKI, Tomasz | Journal Contribution | A1 |
| 85 | 2013 | Progression-Free Survival as a Surrogate for Overall Survival in Advanced/Recurrent Gastric Cancer Trials: A Meta-Analysis | PAOLETTI, Xavier; Oba, Koji; Bang, Yung-Jue; Bleiberg, Harry; Boku, Narikazu; Bouche, Olivier; Fuse, Nozomu; Michiels, Stefan; Moehler, Markus; Morita, Satoshi; Ohashi, Yasuo; Ohtsu, Atsushi; Roth, Arnaud; Rougier, Philippe; Sakamoto, Junichi; Sargent, Daniel; Sasako, Mitsuru; Shitara, Kohei; Thuss-Patience, Peter; Van Cutsem, Eric; BURZYKOWSKI, Tomasz; BUYSE, Marc | Journal Contribution | A1 |
| 86 | 2013 | Omics-based clinical trial designs | BUYSE, Marc; Michiels, Stefan | Journal Contribution | A1 |
| 87 | 2013 | Comparison of treatment effect sizes associated with surrogate and final patient relevant outcomes in randomised controlled trials: meta-epidemiological study | Ciani, Oriana; BUYSE, Marc; Garside, Ruth; Pavey, Toby; Stein, Ken; Sterne, Jonathan A. C.; Taylor, Rod S. | Journal Contribution | A1 |
| 88 | 2012 | A statistical approach to central monitoring of data quality in clinical trials | Venet, David; Doffagne, Erik; BURZYKOWSKI, Tomasz; Beckers, Francois; Tellier, Yves; Genevois-Marlin, Eric; Becker, Ursula; Bee, Valerie; Wilson, Veronique; LEGRAND, Catherine; BUYSE, Marc | Journal Contribution | A1 |
| 89 | 2012 | Predicting Treatment Effect from Surrogate Endpoints and Historical Trials: An Extrapolation Involving Probabilities of a Binary Outcome or Survival to a Specific Time | Baker, Stuart G.; Sargent, Daniel J.; BUYSE, Marc; BURZYKOWSKI, Tomasz | Journal Contribution | A1 |
| 90 | 2011 | Individual patient data meta-analysis of randomized trials evaluating IL-2 monotherapy as remission maintenance therapy in acute myeloid leukemia | BUYSE, Marc; Squifflet, Pierre; Lange, Beverly J.; Alonzo, Todd A.; Larson, Richard A.; Kolitz, Jonathan E.; George, Stephen L.; Bloomfield, Clara D.; Castaigne, Sylvie; Chevret, Sylvie; Blaise, Didier; Maraninchi, Dominique; Lucchesi, Kathryn J.; BURZYKOWSKI, Tomasz | Journal Contribution | A1 |
| 91 | 2011 | Comparative assessment of trial-level surrogacy measures for candidate time-to-event surrogate endpoints in clinical trials | Shi, Qian; Renfro, Lindsay A.; Bot, Brian M.; BURZYKOWSKI, Tomasz; BUYSE, Marc; Sargent, Daniel J. | Journal Contribution | A1 |
| 92 | 2011 | Multicenter Phase III Randomized Trial Comparing Docetaxel and Trastuzumab With Docetaxel, Carboplatin, and Trastuzumab As First-Line Chemotherapy for Patients With HER2-Gene-Amplified Metastatic Breast Cancer (BCIRG 007 Study): Two Highly Active Therapeutic Regimens | Valero, Vicente; Forbes, John; Pegram, Mark D.; Pienkowski, Tadeusz; Eiermann, Wolfgang; von Minckwitz, Gunter; Roche, Henri; Martin, Miguel; Crown, John; Mackey, John R.; Fumoleau, Pierre; Rolski, Janusz; Mrsic-Krmpotic, Zrinka; Jagiello-Gruszfeld, Agnieszka; Riva, Alessandro; BUYSE, Marc; Taupin, Henry; Sauter, Guido; Press, Michael F.; Slamon, Dennis J. | Journal Contribution | A1 |
| 93 | 2011 | Leukemia-free survival as a surrogate end point for overall survival in the evaluation of maintenance therapy for patients with acute myeloid leukemia in complete remission | BUYSE, Marc; Michiels, Stefan; Squifflet, Pierre; Lucchesi, Kathryn J.; Hellstrand, Kristoffer; Brune, Mats L.; Castaigne, Sylvie; Rowe, Jacob M. | Journal Contribution | A1 |
| 94 | 2011 | Progression-free survival as a primary endpoint in clinical trials of metastatic colorectal cancer | Gill, S.; Berry, S.; Biagi, J.; Butts, C.; BUYSE, Marc; Chen, E.; Jonker, D.; Marginean, C.; Samson, B.; Stewart, J.; Thirlwell, M.; Wong, R.; Maroun, J. A. | Journal Contribution | A1 |
| 95 | 2011 | Assessment of the consistency and robustness of results from a multicenter trial of remission maintenance therapy for acute myeloid leukemia | BUYSE, Marc; Squifflet, Pierre; Lucchesi, Kathryn J.; Brune, Mats L.; Castaigne, Sylvie; Rowe, Jacob M. | Journal Contribution | A1 |
| 96 | 2010 | Generalized pairwise comparisons of prioritized outcomes in the two-sample problem | BUYSE, Marc | Journal Contribution | A1 |
| 97 | 2010 | A unified framework for the evaluation of surrogate endpoints in mental-health clinical trials | MOLENBERGHS, Geert; BURZYKOWSKI, Tomasz; ALONSO ABAD, Ariel; ASSAM NKOUIBERT, Pryseley; Tilahun, Abel; BUYSE, Marc | Journal Contribution | A1 |
| 98 | 2010 | Benefit of Adjuvant Chemotherapy for Resectable Gastric Cancer A Meta-analysis | PAOLETTI, Xavier; Oba, Koji; BURZYKOWSKI, Tomasz; Michiels, Stefan; Ohashi, Yasuo; Pignon, Jean-Pierre; Rougier, Philippe; Sakamoto, Junichi; Sargent, Daniel; Sasako, Mitsuru; Van Cutsem, Eric; BUYSE, Marc | Journal Contribution | A1 |
| 99 | 2010 | The correlation structure of longitudinal measurements of vision in patients with macular degeneration. | BURZYKOWSKI, Tomasz; BUYSE, Marc | Journal Contribution | A1 |
| 100 | 2009 | Radiological tumor size decrease at week 6 is a potent predictor of outcome in chemorefractory metastatic colorectal cancer treated with cetuximab (BOND trial) | Piessevaux, H.; BUYSE, Marc; De Roock, W.; Prenen, H.; Schlichting, M.; Van Cutsem, E.; Tejpar, S. | Journal Contribution | A1 |
| 101 | 2009 | Contributions of meta-analyses based on individual patient data to therapeutic progress in colorectal cancer | BUYSE, Marc | Journal Contribution | A1 |
| 102 | 2009 | Surrogate endpoints for overall survival in locally advanced head and neck cancer: meta-analyses of individual patient data | Michiels, Stefan; Le Maitre, Aurelie; BUYSE, Marc; BURZYKOWSKI, Tomasz; Maillard, Emilie; Bogaerts, Jan; Vermorken, Jan B.; Budach, Wilfried; Pajak, Thomas F.; Ang, Kian K.; Bourhis, Jean; Pignon, Jean-Pierre | Journal Contribution | A1 |
| 103 | 2009 | Use of Meta-Analysis for the Validation of Surrogate Endpoints and Biomarkers in Cancer Trials | BUYSE, Marc | Journal Contribution | A1 |
| 104 | 2008 | European regulatory agencies should employ full time statisticians | Hughes, Sara; Keene, Oliver; Howitt, Nigel; Roes, Kit; Ashby, Deborah; Beltangady, Mohan; Bird, Sheila M.; Burton, Catherine; BUYSE, Marc; Day, Simon; van Ewijk, Peter; Fletcher, Chrissie; Grieve, Andrew P.; Guinot, Christiane; Hand, David J.; Hemmings, Rob; Holt, D.; Hothorn, Ludwig; Jagers, Peter; Keiding, Niels; Korhonen, Pasi; LESAFFRE, Emmanuel; Lewis, John A.; MOLENBERGHS, Geert; Neumann, Norbert; Olsen, Klaus Juel; van Osta, Gonnie; Pocock, Stuart; Rockhold, Frank; Rossi, Andrea; Senn, Stephen; Stijnen, Theo; Vaeth, Michael; Wiklund, Stig Johan; Wolfram, Josephine | Journal Contribution | A1 |
| 105 | 2008 | Ensuring trial validity by data quality assurance and diversification of monitoring methods | Baigent, C.; Harrell, F.; BUYSE, Marc; Emberson, J.; Altman, D. | Proceedings Paper | C1 |
| 106 | 2008 | Post-Consolidation Immunotherapy with Histamine Dihydrochloride and Interleukin-2 in AML: Assessment of Consistency and Robustness of Treatment Benefit for Patients in First Complete Remission. | BUYSE, Marc; Squifflet, Pierre; Rowe, Jacob M.; Whisnant, John K.; Bhagwat, Dileep; Allard, Stephane E.; Hellstrand, Kristoffer; Brune, Mats L. | Journal Contribution | M |
| 107 | 2008 | Evaluation of tumor response, disease control, progression-free survival, and time to progression as potential surrogate end points in metastatic breast cancer | BURZYKOWSKI, Tomasz; BUYSE, Marc; Piccart-Gebhart, Martine J.; Sledge, George; Carmichael, James; Lueck, Hans-Joachim; Mackey, John R.; Nabholtz, Jean-Marc; Paridaens, Robert; Biganzoli, Laura; Jassem, Jacek; Bontenbal, Marijke; Bonneterre, Jacques; Chan, Stephen; Basaran, Gul Atalay; Therasse, Patrick | Journal Contribution | A1 |
| 108 | 2008 | The meta-analytic framework for the evaluation of surrogate endpoints in clinical trials | MOLENBERGHS, Geert; BURZYKOWSKI, Tomasz; ALONSO ABAD, Ariel; ASSAM NKOUIBERT, Pryseley; TILAHUN ESHETE, Abel; BUYSE, Marc | Journal Contribution | A1 |
| 109 | 2008 | Exploring and validating surrogate endpoints in colorectal cancer | BURZYKOWSKI, Tomasz; BUYSE, Marc; Yothers, Greg; Sakamoto, Junichi; Sargent, Dan | Journal Contribution | A1 |
| 110 | 2008 | Endpoints and surrogate endpoints in colorectal cancer: a review of recent developments | PIEDBOIS, P.; BUYSE, Marc | Journal Contribution | A1 |
| 111 | 2008 | Taxanes alone or in combination with anthracyclines as first-line therapy of patients with metastatic breast cancer | Piccart-Gebhart, Martine J.; BURZYKOWSKI, Tomasz; BUYSE, Marc; Sledge, George; Carmichael, James; Luck, Hans-Joachim; Mackey, John R.; Nabholtz, Jean-Marc; Paridaens, Robert; Biganzoli, Laura; Jassem, Jacek; Bontenbal, Marijke; Bonneterre, Jacques; Chan, Stephen; Basaran, Gul Atalay; Therasse, Patrick | Journal Contribution | A1 |
| 112 | 2008 | Individual- and trial-level surrogacy in colorectal cancer | BUYSE, Marc; BURZYKOWSKI, Tomasz; Michiels, Stefan; Carroll, Kevin | Journal Contribution | A1 |
| 113 | 2008 | Reformulating the hazard ratio to enhance communication with clinical investigators | BUYSE, Marc | Journal Contribution | A1 |
| 114 | 2007 | Are prostate-specific antigen changes valid surrogates for survival in hormone-refractory prostate cancer? A meta-analysis is needed! | Collette, Laurence; BUYSE, Marc; BURZYKOWSKI, Tomasz | Journal Contribution | A1 |
| 115 | 2007 | Reintroduction of oxaliplatin is associated with improved survival in advanced colorectal cancer | de Gramont, Aimery; BUYSE, Marc; CORTINAS ABRAHANTES, Jose; BURZYKOWSKI, Tomasz; Quinaux, Emmanuel; Cervantes, Andres; Figer, Arie; Lledo, Gerard; Flesch, Michel; Mineur, Laurent; Carola, Elisabeth; Etienne, Pierre-Luc; Rivera, Fernando; Chirivella, Isabel; Perez-Staub, Nathalie; Louvet, Christophe; André, Thierry; Tabah-Fisch, Isabelle; Tournigand, Christophe | Journal Contribution | A1 |
| 116 | 2007 | Progression-free survival is a surrogate for survival in advanced colorectal cancer | BUYSE, Marc; BURZYKOWSKI, Tomasz; Carroll, Kevin; Michiels, Stefan; Sargent, Daniel J.; Miller, Langdon L.; Elfring, Gary L.; Pignon, Jean-Pierre; Piedbois, Pascal | Journal Contribution | A1 |
| 117 | 2006 | Gene signature evaluation as a prognostic tool: challenges in the design of the MINDACT trial | Bogaerts, J.; Cardoso, F.; BUYSE, Marc; Braga, S.; Loi, S.; Harrison, J. A.; Bines, J.; Mook, S.; Decker, N.; Ravdin, P.; Therasse, P.; Rutgers, E.; van't Veer, L. J.; Piccart, M. | Journal Contribution | A1 |
| 118 | 2006 | Alternative clinical end points in rectal cancer—are we getting closer? | Glynne-Jones, R; Mawdsley, S; Pearce, T; BUYSE, Marc | Journal Contribution | A1 |
| 119 | 2006 | Analysis of oxaliplatin reintroduction in patients with advanced colorectal cancer (CRC) treated with FOLFOX4 or FOLFOX7 in the optimox study | BUYSE, Marc; Quinaux, E; CORTINAS ABRAHANTES, Jose; Tournigand, C; Cervantes, A; Figer, A; André, Thierry; Tabah-Fisch, I; De Gramont, A | Journal Contribution | M |
| 120 | 2006 | Current issues in adjuvant treatment of stage II colon cancer | André, Thierry; Sargent, D; Tabernero, J; O'Connell, M; BUYSE, Marc; Sobrero, A; Misset, J.L.; Boni, C; de Gramont, A | Journal Contribution | A1 |
| 121 | 2006 | Surrogate threshold effect: An alternative measure for meta-analytic surrogate endpoint validation | BURZYKOWSKI, Tomasz; BUYSE, Marc | Journal Contribution | A1 |
| 122 | 2006 | A unifying approach for surrogate marker validation based on Prentice's criteria | ALONSO ABAD, Ariel; MOLENBERGHS, Geert; GEYS, Helena; BUYSE, Marc; VANGENEUGDEN, Tony | Journal Contribution | A1 |
| 123 | 2005 | Setting the scene | MOLENBERGHS, Geert; BUYSE, Marc; BURZYKOWSKI, Tomasz | Book Section | B2 |
| 124 | 2005 | The history of surrogate endpoint validation | MOLENBERGHS, Geert; BUYSE, Marc; BURZYKOWSKI, Tomasz | Book Section | B2 |
| 125 | 2005 | Fraud detection | BUYSE, Marc | Book Section | B3 |
| 126 | 2005 | The evaluation of surrogate endpoints | BURZYKOWSKI, Tomasz; MOLENBERGHS, Geert; BUYSE, Marc | Book | B1 |
| 127 | 2005 | Multicenter trials | BUYSE, Marc | Book Section | B3 |
| 128 | 2005 | Notation and motivating studies | MOLENBERGHS, Geert; BUYSE, Marc; BURZYKOWSKI, Tomasz | Book Section | B2 |
| 129 | 2005 | A meta-analytic validation framework for continuous outcomes | MOLENBERGHS, Geert; BUYSE, Marc; BURZYKOWSKI, Tomasz | Book Section | B2 |
| 130 | 2005 | A quantitative study of tumor response and progression-free survival as surrogate endpoints for overall survival in first-line treatment of metastatic breast cancer | BURZYKOWSKI, Tomasz; Piccart, MJ; Sledge, G; Carmichael, J; Luck, HJ; Mackey, John R.; Nabholtz, JM; Paridaens, R; Biganzoli, L; Jassem, J; Blohmer, JU; Bontenbal, M; Bonneterre, J; Chan, S; Atalay, G.; Therasse, P; BUYSE, Marc | Journal Contribution | M |
| 131 | 2005 | Effects of taxanes alone or in combination with anthracyclines on tumor response, progression-free survival and overall survival in first-line chemotherapy of patients with metastatic breast cancer: an analysis of 4,256 patients randomized in 12 trials | Piccart, MJ; BURZYKOWSKI, Tomasz; Sledge, G; Luck, HJ; Mackey, John R.; Nabholtz, JM; Paridaens, R; Biganzoli, L; Jassem, J; Blohmer, JU; Bontenbal, M; Bonneterre, J; Chan, S; Atalay, G.; Carmichael, J; BUYSE, Marc; Therasse, P | Journal Contribution | M |
| 132 | 2005 | Disease-free survival versus overall survival as a primary end point for adjuvant colon cancer studies: individual patient data from 20,898 patients on 18 tandomized trials | Sargent, Daniel J.; Wieand, Harry S.; Haller, Daniel G.; Gray, Richard; Benedetti, Jacqueline; BUYSE, Marc; Labianca, Roberto; Seitz, Jean Francois; O'Callaghan, Christopher J.; Francini, Guido; Grothey, Axel; O'Connell, Michael; Catalano, Paul J.; Blanke, Charles D.; Kerr, David; Green, Erin; Wolmark, Norman; André, Thierry; Goldberg, Richard M.; De Gramont, Aimery | Journal Contribution | A1 |
| 133 | 2005 | Progression-free survival (PFS) as a surrogate for overall survival (OS) in patients with advanced colorectal cancer: An analysis of 3159 patients randomized in 11 trials. | BUYSE, Marc; BURZYKOWSKI, Tomasz; Carroll, K; Michiels, Stefan; Pignon, JP; Piedbois, P | Journal Contribution | M |
| 134 | 2004 | Prentice's approach and the meta-analytic paradigm: a reflection on the role of statistics in the evaluation of surrogate endpoints | ALONSO ABAD, Ariel; MOLENBERGHS, Geert; BURZYKOWSKI, Tomasz; RENARD, Didier; GEYS, Helena; SHKEDY, Ziv; TIBALDI, Fabian; CORTINAS ABRAHANTES, Jose; BUYSE, Marc | Journal Contribution | A1 |
| 135 | 2004 | A perspective on surrogate endpoints in controlled clinical trials | MOLENBERGHS, Geert; BURZYKOWSKI, Tomasz; ALONSO ABAD, Ariel; BUYSE, Marc | Journal Contribution | A1 |
| 136 | 2004 | Efficacy of oral adjuvant therapy after resection of colorectal cancer: 5-year results from three randomized trials | Sakamoto, J.; Ohashi, Y.; Hamada, C.; BUYSE, Marc; BURZYKOWSKI, Tomasz; Piedbois, P. | Journal Contribution | A1 |
| 137 | 2004 | FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study | Tournigand, Christophe; André, Thierry; Achille, Emmanuel; Lledo, Gérard; Flesh, Michel; Mery-Mignard, Dominique; Quinaux, Emmanuel; Couteau, Corinne; BUYSE, Marc; Ganem, Gérard; Landi, Bruno; Colin, Philippe; Louvet, Christophe; de Gramont, Aimery | Journal Contribution | A1 |
| 138 | 2004 | Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: an updated meta-analysis | BUYSE, Marc; et al | Journal Contribution | A1 |
| 139 | 2004 | The validation of surrogate endpoints by using data from randomized clinical trials: a case-study in advanced colorectal cancer | BURZYKOWSKI, Tomasz; MOLENBERGHS, Geert; BUYSE, Marc | Journal Contribution | A1 |
| 140 | 2003 | Overall survival is not a realistic endpoint for clinical trials in advanced solid tumors: a critical assessment based on recently reported phase III trials in colorectal and breast cancer | Di Leo, A.; Bleiberg, H.; BUYSE, Marc | Journal Contribution | A1 |
| 141 | 2003 | Validation of biomarkers as surrogates for clinical endpoints | BUYSE, Marc; VANGENEUGDEN, Tony; BIJNENS, Luc; RENARD, Didier; BURZYKOWSKI, Tomasz; GEYS, Helena; MOLENBERGHS, Geert | Book Section | B3 |
| 142 | 2003 | Comparaison entre LV5FU2 bi-mensuel et FUFOL mensuel pendant 24 ou 36 semaines en traitement adjuvant des cancers du colon stade II et III: résultats à 4 ans d'une étude randomisée | BUYSE, Marc; André, Thierry; Artru, P.; Gamelin, E.; Bouche, O.; Achille, Emmanuel; Piedbois, P.; Flesch, M.; Tubiana-Mathieu, N.; de Gramont, A. | Journal Contribution | A2 |
| 143 | 2003 | Simplified hierarchical linear models for the evaluation of surrogate endpoints | TIBALDI, Fabian; CORTINAS ABRAHANTES, Jose; MOLENBERGHS, Geert; RENARD, Didier; BURZYKOWSKI, Tomasz; BUYSE, Marc; Parmar, Mahesh; Stijnen, Theo; Wolfinger, Russ | Journal Contribution | A1 |
| 144 | 2003 | Using the 'expected' survival to explain differences between the results of randomized trials: a case in advanced ovarian cancer | BUYSE, Marc; BURZYKOWSKI, Tomasz; Parmar, Mahesh; Torri, Valter; Omura, George; Colombo, Nicoletta; Williams, Chris; Conte, Pierfranco; Vermorken, Jan | Journal Contribution | A1 |
| 145 | 2003 | Validation of a longitudinally measured surrogate for a time-to-event endpoint | RENARD, Didier; GEYS, Helena; MOLENBERGHS, Geert; BURZYKOWSKI, Tomasz; BUYSE, Marc; VANGENEUGDEN, Tony; BIJNENS, Luc | Journal Contribution | A1 |
| 146 | 2003 | Semimonthly Versus Monthly Regimen of Fluorouracil and Leucovorin Administered for 24 or 36 Weeks as Adjuvant Therapy in Stage II and III Colon Cancer: Results of a Randomized Trial | BUYSE, Marc; André, Thierry; Colin, P.; Liouvet, C.; Gamelin, E.; Bouche, O.; Achille, Emmanuel; Colbert, N.; Boaziz, C.; Piedbois, P.; Tubiana-Mathieu, N.; Boutan-Laroze, A.; Flesch, M.; Billau, V.; de Gramont, A. | Journal Contribution | A1 |
| 147 | 2002 | Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early cancer: first results of the ATAC randomized trial | BUYSE, Marc | Journal Contribution | A1 |
| 148 | 2002 | Statistical challenges in the evaluation of surrogate endpoints in randomized trials | MOLENBERGHS, Geert; BUYSE, Marc; GEYS, Helena; RENARD, Didier; BURZYKOWSKI, Tomasz; ALONSO ABAD, Ariel | Journal Contribution | A1 |
| 149 | 2002 | Challenges in the methodology for the validation of surrogate endpoints in randomized trials | MOLENBERGHS, Geert; BUYSE, Marc; GEYS, Helena; RENARD, Didier; BURZYKOWSKI, Tomasz | Proceedings Paper | C2 |
| 150 | 2002 | The role of colony stimulating factors in small cell cancer: why the question is still unresolved | Trillet-Lenoir, V.; Piedbois, R.; BUYSE, Marc | Journal Contribution | A1 |
| 151 | 2002 | Equivalence between ovarian suppression and chemotherapy in the adjuvant treatment of endocrine-responsive breast cancer | DiLeo, A.; BUYSE, Marc | Journal Contribution | A1 |
| 152 | 2002 | Validation of surrogate endpoints in multiple randomized clinical trials with discrete outcomes | RENARD, Didier; GEYS, Helena; MOLENBERGHS, Geert; BURZYKOWSKI, Tomasz; BUYSE, Marc | Journal Contribution | A1 |
| 153 | 2001 | Methodology for the validation of surrogate endpoints in multiple randomized experiments | MOLENBERGHS, Geert; ALONSO ABAD, Ariel; BURZYKOWSKI, Tomasz; CORTINAS ABRAHANTES, Jose; GEYS, Helena; RENARD, Didier; SHKEDY, Ziv; TIBALDI, Fabian; BUYSE, Marc | Proceedings Paper | C2 |
| 154 | 2001 | Methodology of the validation of surrogate endpoints in multiple randomized experiments | MOLENBERGHS, Geert; ALONSO ABAD, Ariel; BURZYKOWSKI, Tomasz; CORTINAS ABRAHANTES, Jose; GEYS, Helena; RENARD, Didier; SHKEDY, Ziv; TIBALDI, Fabian; BUYSE, Marc | Proceedings Paper | C2 |
| 155 | 2001 | Validation of surrogate endpoints in multiple randomized clinical trials with failure-time endpoints | BURZYKOWSKI, Tomasz; MOLENBERGHS, Geert; BUYSE, Marc; GEYS, Helena; RENARD, Didier | Journal Contribution | A1 |
| 156 | 2001 | Re: A model to select chemotherapy regimens for phase III trials for extensive-stage small-cell lung cancer | BUYSE, Marc; Thirion, Pierre; Carlson, Robert; BURZYKOWSKI, Tomasz; MOLENBERGHS, Geert; Piedbois, Pascal | Journal Contribution | A1 |
| 157 | 2001 | Evaluation of surrogate endpoints in randomized experiments with mixed discrete and continuous outcomes | MOLENBERGHS, Geert; GEYS, Helena; BUYSE, Marc | Journal Contribution | A1 |
| 158 | 2001 | Should Dukes' B patients receive adjuvant therapy? A statistical perspective | BUYSE, Marc; Piedbois, P | Journal Contribution | A1 |
| 159 | 2000 | Validation of surrogate endpoints in multiple randomized clinical trials with failure-time endpoints | BURZYKOWSKI, Tomasz; MOLENBERGHS, Geert; BUYSE, Marc; GEYS, Helena; RENARD, Didier | Proceedings Paper | C1 |
| 160 | 2000 | Randomized designs for early trials of new cancer treatments - An overview | BUYSE, Marc | Journal Contribution | A1 |
| 161 | 2000 | Relation between tumour response to first-line chemotherapy and survival in advanced colorectal cancer: a meta-analysis | BUYSE, Marc; Thirion, Pierre; Carlson, Robert W.; BURZYKOWSKI, Tomasz; MOLENBERGHS, Geert; Piedbois, Pascal | Journal Contribution | A1 |
| 162 | 2000 | Meta-analysis: Methods, strengths, and weaknesses | BUYSE, Marc; Piedbois, P; Piedbois, Y; Carlson, RW | Journal Contribution | A1 |
| 163 | 2000 | R-2: A useful measure of model performance when predicting a dichotomous outcome | BUYSE, Marc | Journal Contribution | A1 |
| 164 | 2000 | Fraud in medical research: An international survey of biostatisticians | Ranstam, J.; BUYSE, Marc; George, S.L.; Evans, S.; Geller, N.; Scherrer, B.; LESAFFRE, Emmanuel; Murray, G.; Edler, L.; Hutton, J.; Colton, T.; Lachenbruch, P. | Journal Contribution | A1 |
| 165 | 2000 | Statistical validation of surrogate endpoints: problems and proposals | BUYSE, Marc; MOLENBERGHS, Geert; BURZYKOWSKI, Tomasz; RENARD, Didier; GEYS, Helena | Journal Contribution | A1 |
| 166 | 2000 | Corrigendum to "The validation of surrogate endpoints in randomized experiments" | BUYSE, Marc; MOLENBERGHS, Geert; BURZYKOWSKI, Tomasz | Journal Contribution | M |
| 167 | 2000 | The validation of surrogate endpoints in meta-analyses of randomized experiments | BUYSE, Marc; MOLENBERGHS, Geert; BURZYKOWSKI, Tomasz; RENARD, Didier; GEYS, Helena | Journal Contribution | A1 |
| 168 | 1999 | The role of biostatistics in the prevention, detection and treatment of fraud in clinical trials | BUYSE, Marc; George, SL; Evans, S; Geller, NL; Ranstam, J; Scherrer, B; LESAFFRE, Emmanuel; Murray, G; Edler, L; Hutton, J; Colton, T; Lachenbruch, P; Verma, BL | Journal Contribution | |
| 169 | 1999 | Meta-analyses of published results are unreliable | BUYSE, Marc; Carlson, RW; Piedbois, P | Journal Contribution | |
| 170 | 1999 | The validation of surrogate endpoints in meta-analyses of randomized experiments | BUYSE, Marc; MOLENBERGHS, Geert; BURZYKOWSKI, Tomasz; RENARD, Didier; GEYS, Helena | Proceedings Paper | |
| 171 | 1999 | The role of anthracyclines in epithelial ovarian cancer | Vermorken, J.B.; Harper, P.G.; BUYSE, Marc | Journal Contribution | |
| 172 | 1998 | Anemia in children with cancer is associated with decreased erythropoietic activity and not with inadequate erythropoietin production | Corazza, F.; Beguin, Y.; Bergman, P.; André, M.; Fersten, A.; DE VALCK, Chris; Fondu, P.; BUYSE, Marc; Saribau, E. | Journal Contribution | |
| 173 | 1998 | Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced coloractal cancer | BUYSE, Marc | Journal Contribution | |
| 174 | 1998 | Toxiicity of 5-fluorouacil in patients with advanced colorectal cancer: effect of administration schedule and prognostic factors | BUYSE, Marc | Journal Contribution | |
| 175 | 1998 | Homeopathy | BUYSE, Marc | Journal Contribution | |
| 176 | 1998 | Criteria for the validation of surrogate endpoints in randomized experiments | BUYSE, Marc; MOLENBERGHS, Geert | Journal Contribution | |
| 177 | 1997 | The trials of Dr. Bernard Fisher: a European perspective on an American episode | Peto, R.; Collins, R.; Sackett, D.; Darbyshire, J.; Babiker, A.; BUYSE, Marc; Stewart, H.; Baum, M.; Goldhirsch, H.; Bonadonna, G.; Valagussa, P.; Rutqvist, L.; Elbourne, D.; Davies, C.; Dalesio, O.; Parmar, M.; Hill, C.; Clarke, M.; Gray, R.; Doll, R. | Journal Contribution | |
| 178 | 1997 | Long-term results of lung metastasectomy: prognostic analyses based on 5206 cases | Pastorino, U.; BUYSE, Marc; Friedel, G.; Ginsberg, R.J.; Girard, P.; Goldstraw, P.; Johnston, M.; McCormack, P.; Pass, H.; Putman, J.B. | Journal Contribution | |
| 179 | 1997 | A biostatistical tribute to Ignaz Philip Semmelweis | BUYSE, Marc | Journal Contribution | |
| 180 | 1997 | Economic implications of hepatic arterial infusion chemotherapy in treatment of nonresectable colorectal liver metastases. Meta-Analysis Group in Cancer | Durand-Zaleski, I.; Roche, B.; BUYSE, Marc; Carlson, R.; O'Connell, M.J.; Rougier, P.; Chang, A.E.; Sondak, V.K.; Kemeny, M.M.; Allen-Merch, T.G.; Fagniez, P.L.; le Bourgeois, J.P.; Piedbois, P. | Journal Contribution | |
| 181 | 1997 | Letter to the editor: artificial neural networks | BUYSE, Marc; Piedbois, P. | Journal Contribution | |
| 182 | 1997 | Artificial neural networks | BUYSE, Marc; Piedbois, P | Journal Contribution | |
| 183 | 1997 | Critical issues in colorectal cancer trial design | Piedbois, P.; BUYSE, Marc; Pignon, J.P. | Journal Contribution | |
| 184 | 1997 | La randomisation dans les essais cliniques | BUYSE, Marc; Piedbois, P. | Journal Contribution | |
| 185 | 1996 | Le 5-fluorouracile...un vieux médicament? | Piedbois, P.; BUYSE, Marc; Gauthier, E.; le Bourgeois, J.P. | Journal Contribution | |
| 186 | 1996 | Etablissement d'une courbe de survie | BUYSE, Marc; Piedbois, P. | Journal Contribution | |
| 187 | 1996 | The role of intervention debulking surgery in advanced epithelial ovarian cancer: an EORTC gynecological cancer cooperative group study | van der Burg, M.E.L.; van Lent, M.; BUYSE, Marc; Kobierska, A.; Maggioni, A.; Favalli, G.; Lacave, A.J.; Nardi, M.; Renard, J.; Pecorelli, S. | Journal Contribution | |
| 188 | 1996 | Phase III randomized study to compare interferon alfa-2a in combination with fluorouracil versus fluorouracil alone in patients with advanced colorectal cancer | Greco, F.A.; Figlin, R.; York, M.; Einhorn, L.; Schilsky, R.; Marshall, E.M.; Buys, S.S.; Froimtchuk, M.J.; Schuller, J.; Schuchter, L.; BUYSE, Marc; RITTER, Linda; Man, A.; Yap, A.K.L. | Journal Contribution | |
| 189 | 1996 | Hydroxyurea for treatment of severe sickle cell anemia: a pediatric clinical trial | Ferster, A.; Vermylen, C.; Cornu, G.; BUYSE, Marc; Corazza, F.; DE VALCK, Chris; Fondu, P.; Toppet, M.; Sariban, E. | Journal Contribution | |
| 190 | 1996 | On the relationship between response to treatment and survival time | BUYSE, Marc; Piedbois, P | Journal Contribution | |
| 191 | 1996 | Meta-analysis group in cancer: reappraisal of hepatic arterial infusion in the treatment of non resectable liver metastases from colorectal cancer | BUYSE, Marc | Journal Contribution | |
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