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Title: | Looking into the eye of patients with chronic obstructive pulmonary disease: an opportunity for better microvascular profiling of these complex patients | Authors: | Vaes, Anouk W. SPRUIT, Martijn A. THEUNIS, Jan Goswami, Nandu Vanfleteren, Lowie E. Franssen, Frits M. E. Wouters, Emiel F. M. DE BOEVER, Patrick |
Issue Date: | 2018 | Publisher: | WILEY | Source: | ACTA OPHTHALMOLOGICA, 96(6), p. 539-549 | Abstract: | Chronic obstructive pulmonary disease (COPD) is a complex disease with many patients suffering from cardiovascular comorbidity. However, cardiovascular diseases remain often undiagnosed in COPD. Assessment of the retinal microvasculature can provide value in cardiovascular profiling of these patients. Retinal microvascular assessment carried out via a noninvasive eye exam represents an easy to use tool when examining patients with COPD. The purpose of this review was to provide an overview of studies assessing structural and functional changes in the retinal microvasculature of patients with COPD. Findings demonstrated that structural and functional microvascular changes were more common and severe in COPD patients as compared to non-COPD controls, although few retinal investigations have been performed in patients with COPD. As cardiovascular comorbidities are highly prevalent in COPD, we advocate more research to investigate the value of an eye exam for microvascular phenotyping of COPD patients. | Notes: | [Vaes, Anouk W.; Spruit, Martijn A.; Vanfleteren, Lowie E.; Franssen, Frits M. E.; Wouters, Emiel F. M.] Ciro, Dept Res & Educ, Hornerheide 1, NL-6085 NM Horn, Netherlands. [Vaes, Anouk W.; Theunis, Jan; De Boever, Patrick] Flemish Inst Technol Res VITO, Environm Risk & Hlth Unit, Mol, Belgium. [Spruit, Martijn A.; Vanfleteren, Lowie E.; Franssen, Frits M. E.; Wouters, Emiel F. M.] Maastricht Univ, Med Ctr, Dept Resp Med, NUTRIM Sch Nutr & Translat Res Metab, Maastricht, Netherlands. [Spruit, Martijn A.] Hasselt Univ, Fac Med & Life Sci, REVAL Rehabil Res Ctr, BIOMED Biomed Res Inst, Diepenbeek, Belgium. [Goswami, Nandu] Otto Loewi Ctr Res Vasc Biol Immun & Inflammat, Chair Physiol Unit, Graz, Austria. [De Boever, Patrick] Hasselt Univ, Ctr Environm Sci, Hasselt, Belgium. | Keywords: | cardiovascular disease; chronic obstructive pulmonary disease; colour Doppler ultrasonography; microvasculature; optical coherence tomography; retinal fundus imaging; retinal oximetry;cardiovascular disease; chronic obstructive pulmonary disease; colour Doppler ultrasonography; microvasculature; optical coherence tomography; retinal fundus imaging; retinal oximetry | Document URI: | http://hdl.handle.net/1942/27899 | ISSN: | 1755-375X | e-ISSN: | 1755-3768 | DOI: | 10.1111/aos.13765 | ISI #: | 000447257100001 | Rights: | Copyright 2018 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2019 |
Appears in Collections: | Research publications |
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