Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/14722
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | TOMSIN, Kathleen | - |
dc.contributor.author | Mesens, Tinne | - |
dc.contributor.author | OBEN, Jolien | - |
dc.contributor.author | MOLENBERGHS, Geert | - |
dc.contributor.author | Peeters, Louis | - |
dc.contributor.author | GYSELAERS, Wilfried | - |
dc.date.accessioned | 2013-03-19T12:43:18Z | - |
dc.date.available | 2013-03-19T12:43:18Z | - |
dc.date.issued | 2012 | - |
dc.identifier.citation | 18th World Congress of International Society for the Study of Hypertension in Pregnancy, Geneva, Switzerland, 9-12 July 2012 | - |
dc.identifier.uri | http://hdl.handle.net/1942/14722 | - |
dc.description.abstract | Introduction: Reflex responses of cardiac cycle time intervals (CCTI) can be measured by echocardiography, and are reported to differ between uneventful pregnancy (UP) and pre-eclampsia(PE). It is unknown whether impedance cardiography (ICG) is a useful method to measure CCTI during pregnancy. Objectives: ICG measurements of CCTI before and after orthostatic challenge are evaluated in UP and in the clinical phase of PE. Methods: Examinations were performed twice in 16 UP (30–36 weeks), and once in 30 early PE (EPE, <34 weeks) and in 32 late PE (LPE, 34 weeks). A 3rd generation ICG device using a 4 electrode arrangement (NICCOMO, Medis, Germany) was used to measure CCTI in supine position and after moving to upright position. The pre-ejection period (PEP) is the time-interval between ventricular depolarisation and start of aortic flow. The left ventricular ejection time (LVET) is the time-interval between opening and closing of the aortic valve. Diastolic time (DT) is heart period duration – (PEP+LVET). Orthostatic-induced changes from supine to upright position (cardiac reflex response or CRR) were evaluated using One-sample Wilcoxon Signed Rank Tests. All CRRs in EPE and LPE were compared to UP using Mann-Whitney U tests. Data are represented as medians (interquartile ranges). Results: Maternal age was comparable between all groups [29 (26–32) years; p0.47]. Gestational age was comparable between both early [31 (28–32) vs 31 (27–33) weeks] and late [37 (36–39) vs 38 (36–39) weeks] third trimester UP and PE [p0.38]. Pre-gestational BMI was higher in EPE compared to UP [26 (24–32) vs 23 (21–24); p<0.01]. This was not true for LPE [25 (23–28); p=0.06]. Birth weight percentiles were lower in both EPE and LPE compared to UP [UP: 44 (38–78), EPE: 18 (5–28), LPE: 31 (18–59); p<0.05], and also lower in EPE compared to LPE [p=0.03]. CRRs within each group are shown in Table 1. The CRRs of PEP were significantly different between UP and both EPE and LPE [p⩽0.01], due to orthostatic-induced increase in PE but not in UP. Conclusion: Our study confirms that orthostasis does not change PEP in UP but induces a significant increase of PEP in PE. The increased reflex-induced duration of isovolumetric contraction time can be explained by a decreased left ventricular performance in the clinical phase of PE as compared to UP. ICG turns out to be a straightforward and useful method to evaluate these hemodynamic features. | - |
dc.language.iso | en | - |
dc.title | Impedance cardiography: a straightforward and reliable tool to evaluate differences of cardiac reflex response between normal pregnancy and pre-eclampsia. | - |
dc.type | Conference Material | - |
local.bibliographicCitation.conferencedate | 9-12 July 2012 | - |
local.bibliographicCitation.conferencename | 18th World Congress of International Society for the Study of Hypertension in Pregnancy | - |
local.bibliographicCitation.conferenceplace | Geneva, Switzerland | - |
local.bibliographicCitation.jcat | C2 | - |
local.type.refereed | Refereed | - |
local.type.specified | Presentation | - |
item.accessRights | Closed Access | - |
item.fulltext | No Fulltext | - |
item.contributor | TOMSIN, Kathleen | - |
item.contributor | Mesens, Tinne | - |
item.contributor | OBEN, Jolien | - |
item.contributor | MOLENBERGHS, Geert | - |
item.contributor | Peeters, Louis | - |
item.contributor | GYSELAERS, Wilfried | - |
item.fullcitation | TOMSIN, Kathleen; Mesens, Tinne; OBEN, Jolien; MOLENBERGHS, Geert; Peeters, Louis & GYSELAERS, Wilfried (2012) Impedance cardiography: a straightforward and reliable tool to evaluate differences of cardiac reflex response between normal pregnancy and pre-eclampsia.. In: 18th World Congress of International Society for the Study of Hypertension in Pregnancy, Geneva, Switzerland, 9-12 July 2012. | - |
Appears in Collections: | Research publications |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.