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| | Issue Date | Title | Contributor(s) | Type | Cat. |
| 41 | 2023 | From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions | TIANE, Assia; SCHEPERS, Melissa; Reijnders, Rick A.; VAN VEGGEL, Lieve; CHENINE, Sarah; ROMBAUT, Ben; Dempster, Emma; Verfaillie, Catherine; Wasner, Kobi; Gruenewald, Anne; Prickaerts, Jos; Pishva, Ehsan; HELLINGS, Niels; van den Hove, Daniel; VANMIERLO, Tim | Journal Contribution | A1 |
| 42 | 2023 | Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis | VANMIERLO, Tim; SCHEPERS, Melissa; PAES, Dean; TIANE, Assia; ROMBAUT, Ben; PICCART, Elisabeth; VAN VEGGEL, Lieve; GERVOIS, Pascal; WOLFS, Esther; LAMBRICHTS, Ivo; Brullo, C.; Bruno, O.; Fidele, E.; Ricciarelli, R.; Ffrench-Constant, C.; Bechler, M. E.; van Schaik, P.; Baron, W.; Lefevere , E.; Wasner, K.; Grunewald, A.; Verfaillie, C.; BAETEN, Paulien; BROUX, Bieke; Wieringa, P.; HELLINGS, Niels; Prickaerts, J. | Journal Contribution | M |
| 43 | 2023 | A perspective on causality assessment in epigenetic research on neurodegenerative disorders | KOULOUSAKIS, Philippos; TIANE, Assia; HELLINGS, Niels; Prickaerts, Jos; van den Hove, Daniel; VANMIERLO, Tim | Journal Contribution | A2 |
| 44 | 2023 | Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis | SCHEPERS, Melissa; PAES, Dean; TIANE, Assia; ROMBAUT, Ben; PICCART, Elisabeth; VAN VEGGEL, Lieve; GERVOIS, Pascal; Brullo, Chiara; Bruno, Olga; Fedele, Ernesto; Ricciarelli, Roberta; Ffrench-Constant, Charles; Bechler, Marie E.; Schaik, Pauline van; WOLFS, Esther; LAMBRICHTS, Ivo; Baron, Wia; LEFEVERE, Evy; Wasner, Kobi; Gruenewald, Anne; Verfaillie, Catherine; Wieringa, Paul; Prickaerts, Jos; BROUX, Bieke; BAETEN, Paulien; HELLINGS, Niels; VANMIERLO, Tim | Journal Contribution | A1 |
| 45 | 2023 | Activation of Liver X Receptors and Peroxisome Proliferator-Activated Receptors by Lipid Extracts of Brown Seaweeds: A Potential Application in Alzheimer's Disease? | MARTENS, Nikita; ZHAN, Na; Voortman, Gardi; Leijten, Frank P. J.; van Rheenen, Connor; van Leerdam, Suzanne; Geng, Xicheng; HUYBRECHTS, Michiel; Liu, Hongbing; Jonker, Johan W. W.; Kuipers, Folkert; Lutjohann, Dieter; VANMIERLO, Tim; Mulder, Monique T. T. | Journal Contribution | A1 |
| 46 | 2023 | Cerebral microvascular endothelial cell-derived extracellular vesicles regulate blood - brain barrier function | HOSSEINKHANI, Baharak; DURAN, Gayel; HOEKS, Cindy; HERMANS, Doryssa; SCHEPERS, Melissa; BAETEN, Paulien; POELMANS, Joren; Coenen, Britt; Bekar, Kuebra; Pintelon, Isabel; Timmermans , Jean-Pierre; VANMIERLO, Tim; MICHIELS, Luc; HELLINGS, Niels; BROUX, Bieke | Journal Contribution | A1 |
| 47 | 2023 | Carnosine synthase deficiency aggravates neuroinflammation in multiple sclerosis | SPAAS, Jan; Van der Stede, Thibaux; de Jager, Sarah; VAN DE WATERWEG BERENDS, Annet; TIANE, Assia; Baelde, Hans; Baba, Shahid P.; Eckhardt, Matthias; WOLFS, Esther; VANMIERLO, Tim; HELLINGS, Niels; OP 'T EIJNDE, Bert; Derave, Wim | Journal Contribution | A1 |
| 48 | 2023 | Identification of Side Chain Oxidized Sterols as Novel Liver X Receptor Agonists with Therapeutic Potential in the Treatment of Cardiovascular and Neurodegenerative Diseases | ZHAN, Na; Wang, Boyang; MARTENS, Nikita; Liu , Yankai; Zhao, Shangge; Voortman, Gardi; Van Rooij, Jeroen; Leijten, Frank; VANMIERLO, Tim; Kuipers, Folkert; Jonker, Johan W.; Bloks, Vincent W.; Luetjohann, Dieter; Palumbo, Marcella; Zimetti, Francesca; Adorni, Maria Pia; Liu, Hongbing; Mulder, Monique T. | Journal Contribution | A1 |
| 49 | 2022 | Ponesimod, mono-selective sphingosine-1-phosphate receptor 1 modulator enhances oligodendrocyte precursor cell differentiation | WILLEMS, Emily; SCHEPERS, Melissa; Ait-Tihyaty, M.; VANMIERLO, Tim | Journal Contribution | M |
| 50 | 2022 | The sGC stimulator BAY-747 and activator runcaciguat can enhance memory in vivo via differential hippocampal plasticity mechanisms | NELISSEN, Ellis; Possemis, Nina; Van Goethem, Nick P.; SCHEPERS, Melissa; Mulder-Jongen, Danielle A. J.; Dietz, Lisa; JANSSEN, Wiebke; Gerisch, Michael; Huser, Jorg; Sandner, Peter; VANMIERLO, Tim; Prickaerts, Jos | Journal Contribution | A1 |
| 51 | 2022 | The Selective Sphingosine-1-Phosphate Receptor 1 (S1P1) Modulator Ponesimod Enhances Murine Oligodendrocyte Precursor Cell (OPC) Differentiation and Retains OPC Migration | Ait-Tihyaty, M.; PICCART, Elisabeth; SCHEPERS, Melissa; WILLEMS, E; DiBernardo, A.; VANMIERLO, Tim | Journal Contribution | M |
| 52 | 2022 | Editorial: Cyclic Nucleotide Phosphodiesterases (PDEs) in Immune Regulation and Inflammation | Brocke, Stefan; Epstein, Paul M.; Nelson, Robert; VANMIERLO, Tim | Journal Contribution | A2 |
| 53 | 2022 | The monoselective sphingosine-1-phosphate receptor-1 modulator ponesimod enhances remyelination in the cuprizone model of demyelination | SCHEPERS, Melissa; WILLEMS, Emily; Ait-Tihyaty, M.; VANMIERLO, Tim | Journal Contribution | M |
| 54 | 2022 | Computational investigation of the dynamic control of cAMP signaling by PDE4 isoform types | PAES, Dean; Hermans, Sammy; van den Hove, Daniel; VANMIERLO, Tim; Prickaerts, Jos; Carlier, Aurelie | Journal Contribution | A1 |
| 55 | 2022 | LXR-beta signalling is a key mediator in the pathogenesis of aortic valve stenosis and its prevention by saringosterol | Noethel, M.; Schmidt, A.; Mulder, M. T.; VANMIERLO, Tim; Friedrichs, S.; Schmidt , S. V.; Voortman, G.; Goody, P.; Zimmer, S.; Nickenig, G.; Luetjohann, D.; Jehle, J. | Journal Contribution | M |
| 56 | 2022 | Brown seaweeds activating liver X receptors: Potential role in the prevention of neurodegenerative and cardiometabolic diseases | Mulder, M. T.; MARTENS, Nikita; Zhan , N.; Voortman-Minderman, G.; Liu, H.; Kuipers, F.; Jonker, H.; Luetjohann, D.; VANMIERLO, Tim | Journal Contribution | M |
| 57 | 2022 | The use of seaweed-derived phytosterols to defeat Alzheimer's disease | MARTENS, Nikita; SCHEPERS, Melissa; ZHAN, Na; Leijten, F.; Voortman-Minderman, G.; TIANE, Assia; ROMBAUT, Ben; Poisquet, Janne; Van de Sande, N.; Kerksiek, A.; Kuipers, F.; Jonker, J. W.; Liu, H.; Luetjohann, D.; VANMIERLO, Tim; Mulder, M. T. | Journal Contribution | M |
| 58 | 2022 | Increasing cAMP levels by inhibiting phosphodiesterase 4D improves nerve conduction and functional recovery in a mouse model for Charcot Marie Toot 1A | VANGANSEWINKEL, Tim; SCHEPERS, Melissa; LIBBERECHT, Karen; Jacobs , Darren; PICCART, Elisabeth; JEURISSEN, Hanne; Prior, Robert; Ricciarelli, Roberta; Bruno, Olga; Fedele, Ernesto; Brullo, Chiara; Prickaerts, Jos; Van Den Bosch , Ludo; VANMIERLO, Tim; LAMBRICHTS, Ivo; WOLFS, Esther | Journal Contribution | M |
| 59 | 2021 | The Molecular Biology of Phosphodiesterase 4 Enzymes as Pharmacological Targets: An Interplay of Isoforms, Conformational States, and Inhibitors | PAES, Dean; SCHEPERS, Melissa; ROMBAUT, Ben; van den Hove, Daniel; VANMIERLO, Tim; Prickaerts, Jos; Michel, Martin | Journal Contribution | A1 |
| 60 | 2021 | CSF1R inhibition rescues tau pathology and neurodegeneration in an A/T/N model with combined AD pathologies, while preserving plaque associated microglia | LODDER, Chritica; Scheyltjens, I; STANCU, Ilie Cosmin; BOTELLA LUCENA, Pablo; GUTIERREZ DE RAVE, Manu; VANHERLE, Sarah; VANMIERLO, Tim; CREMERS, Niels; VANRUSSELT, Hannah; BRONE, Bert; Hanseeuw, B; Octave, JN; Bottelbergs, A; Movahedi, K; DEWACHTER, Ilse | Journal Contribution | A1 |
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