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| | Issue Date | Title | Contributor(s) | Type | Cat. |
| 1 | 2023 | Phosphodiesterase (PDE) 4 inhibition boosts Schwann cell myelination in a 3D regeneration model | SCHEPERS, Melissa; Malheiro, Afonso; Gamardo, Adrian Seijas; HELLINGS, Niels; Prickaerts, Jos; Moroni, Lorenzo; VANMIERLO, Tim; Wieringa, Paul | Journal Contribution | A1 |
| 2 | 2023 | sGC modulators as cognitive enhancers: neuronal and/ or vascular? | Prickaerts, Jos; NELISSEN, Ellis; VANMIERLO, Tim; Sandner, Peter | Journal Contribution | M |
| 3 | 2023 | Brain-penetrant sGC stimulator BAY-747 and activator runcaciguat act as cognitive enhancers via differential neuroplastic mechanisms | NELISSEN, Ellis; VANMIERLO, Tim; Sandner, Peter; Prickaerts, Jos | Journal Contribution | M |
| 4 | 2023 | Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-beta pathology | PAES, Dean; SCHEPERS, Melissa; WILLEMS, Emily; ROMBAUT, Ben; TIANE, Assia; Solomina, Yevgeniya; Tibbo, Amy; Blair, Connor; Kyurkchieva, Elka; Baillie, George S.; Ricciarelli, Roberta; Brullo, Chiara; Fedele, Ernesto; Bruno, Olga; van den Hove, Daniel; VANMIERLO, Tim; Prickaerts, Jos | Journal Contribution | A1 |
| 5 | 2023 | From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions | TIANE, Assia; SCHEPERS, Melissa; Reijnders, Rick A.; VAN VEGGEL, Lieve; CHENINE, Sarah; ROMBAUT, Ben; Dempster, Emma; Verfaillie, Catherine; Wasner, Kobi; Gruenewald, Anne; Prickaerts, Jos; Pishva, Ehsan; HELLINGS, Niels; van den Hove, Daniel; VANMIERLO, Tim | Journal Contribution | A1 |
| 6 | 2023 | Soluble guanylyl cyclase: A novel target for the treatment of vascular cognitive impairment? | NELISSEN, Ellis; SCHEPERS, Melissa; PONSAERTS, Laura; Foulquier, Sebastien; BRONCKAERS, Annelies; VANMIERLO, Tim; Sandner, Peter; Prickaerts, Jos | Journal Contribution | A1 |
| 7 | 2023 | A perspective on causality assessment in epigenetic research on neurodegenerative disorders | KOULOUSAKIS, Philippos; TIANE, Assia; HELLINGS, Niels; Prickaerts, Jos; van den Hove, Daniel; VANMIERLO, Tim | Journal Contribution | A2 |
| 8 | 2023 | Exogenous Oxytocin Administration Restores Memory in Female APP/PS1 Mice | KOULOUSAKIS, Philippos; WILLEMS, Emily; SCHEPERS, Melissa; ROMBAUT, Ben; Prickaerts, Jos; VANMIERLO, Tim; van den Hove, Daniel | Journal Contribution | A1 |
| 9 | 2023 | Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis | SCHEPERS, Melissa; PAES, Dean; TIANE, Assia; ROMBAUT, Ben; PICCART, Elisabeth; VAN VEGGEL, Lieve; GERVOIS, Pascal; Brullo, Chiara; Bruno, Olga; Fedele, Ernesto; Ricciarelli, Roberta; Ffrench-Constant, Charles; Bechler, Marie E.; Schaik, Pauline van; WOLFS, Esther; LAMBRICHTS, Ivo; Baron, Wia; LEFEVERE, Evy; Wasner, Kobi; Gruenewald, Anne; Verfaillie, Catherine; Wieringa, Paul; Prickaerts, Jos; BROUX, Bieke; BAETEN, Paulien; HELLINGS, Niels; VANMIERLO, Tim | Journal Contribution | A1 |
| 10 | 2022 | Computational investigation of the dynamic control of cAMP signaling by PDE4 isoform types | PAES, Dean; Hermans, Sammy; van den Hove, Daniel; VANMIERLO, Tim; Prickaerts, Jos; Carlier, Aurelie | Journal Contribution | A1 |
| 11 | 2022 | The sGC stimulator BAY-747 and activator runcaciguat can enhance memory in vivo via differential hippocampal plasticity mechanisms | NELISSEN, Ellis; Possemis, Nina; Van Goethem, Nick P.; SCHEPERS, Melissa; Mulder-Jongen, Danielle A. J.; Dietz, Lisa; JANSSEN, Wiebke; Gerisch, Michael; Huser, Jorg; Sandner, Peter; VANMIERLO, Tim; Prickaerts, Jos | Journal Contribution | A1 |
| 12 | 2022 | INCREASING CAMP LEVELS BY INHIBITING PHOSPHODIESTERASE 4D IMPROVES NERVE CONDUCTION AND FUNCTIONAL RECOVERY IN A MOUSE MODEL FOR CHARCOT MARIE TOOT 1A | VANGANSEWINKEL, Tim; SCHEPERS, Melissa; LIBBERECHT, Karen; Jacobs , Darren; PICCART, Elisabeth; JEURISSEN, Hanne; Prior, Robert; Ricciarelli, Roberta; Bruno, Olga; Fedele, Ernesto; Brullo, Chiara; Prickaerts, Jos; Van Den Bosch , Ludo; VANMIERLO, Tim; LAMBRICHTS, Ivo; WOLFS, Esther | Journal Contribution | M |
| 13 | 2021 | Positive effects of roflumilast on behavior, neuroinflammation, and white matter injury in mice with global cerebral ischemia | Vilhena, Emanuella R.; Bonato, Jessica M.; SCHEPERS, Melissa; Kunieda, Juliana K. C.; Milani, Humberto; VANMIERLO, Tim; Prickaerts, Jos; de Oliveira, Rubia M. W. | Journal Contribution | A1 |
| 14 | 2021 | The Molecular Biology of Phosphodiesterase 4 Enzymes as Pharmacological Targets: An Interplay of Isoforms, Conformational States, and Inhibitors | PAES, Dean; SCHEPERS, Melissa; ROMBAUT, Ben; van den Hove, Daniel; VANMIERLO, Tim; Prickaerts, Jos; Michel, Martin | Journal Contribution | A1 |
| 15 | 2021 | DNA methylation regulates the expression of the negative transcriptional regulators ID2 and ID4 during OPC differentiation | TIANE, Assia; SCHEPERS, Melissa; Riemens, Renzo; ROMBAUT, Ben; VANDORMAEL, Patrick; SOMERS, Veerle; Prickaerts, Jos; HELLINGS, Niels; van den Hove, Daniel; VANMIERLO, Tim | Journal Contribution | A1 |
| 16 | 2021 | PDE inhibition in distinct cell types to reclaim the balance of synaptic plasticity | ROMBAUT, Ben; KESSELS, Sofie; SCHEPERS, Melissa; TIANE, Assia; PAES, Dean; Solomina, Yevgeniya; PICCART, Elisabeth; van den Hove, Daniel; BRONE, Bert; Prickaerts, Jos; VANMIERLO, Tim | Journal Contribution | A1 |
| 17 | 2021 | Increased isoform-specific phosphodiesterase 4D expression is associated with pathology and cognitive impairment in Alzheimer’s disease | PAES, Dean; Lardenoije, Roy; CAROLLO, Riccardo; Roubroeks, Janou A. Y.; SCHEPERS, Melissa; Coleman, Paul; Mastroeni, Diego; Delvaux, Elaine; Pishva, Ehsan; Lunnon, Katie; VANMIERLO, Tim; van den Hove, Daniel; Prickaerts, Jos | Journal Contribution | A1 |
| 18 | 2020 | Sphingosine-1-Phosphate Receptor Modulators and Oligodendroglial Cells: Beyond Immunomodulation | Roggeri, Alessandra; SCHEPERS, Melissa; TIANE, Assia; ROMBAUT, Ben; VAN VEGGEL, Lieve; HELLINGS, Niels; Prickaerts, Jos; Pittaluga, Anna; VANMIERLO, Tim | Journal Contribution | A1 |
| 19 | 2019 | Targeting Phosphodiesterases-Towards a Tailor-Made Approach in Multiple Sclerosis Treatment | SCHEPERS, Melissa; TIANE, Assia; PAES, Dean; SANCHEZ, Selien; ROMBAUT, Ben; PICCART, Elisabeth; Rutten, Bart P. F.; BRONE, Bert; HELLINGS, Niels; Prickaerts, Jos; VANMIERLO, Tim | Journal Contribution | A1 |
| 20 | 2018 | Roflumilast promotes memory recovery and attenuates white matter injury in aged rats subjected to chronic cerebral hypoperfusion | Santiago, Amanda; Soares, Ligia Mendes; SCHEPERS, Melissa; Milani, Humberto; VANMIERLO, Tim; Prickaerts, Jos; Weffort de Oliveira, Rubia M. | Journal Contribution | A1 |
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