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| | Issue Date | Title | Contributor(s) | Type | Cat. |
| 1 | 2025 | APOE deficiency inhibits amyloid-facilitated (A) tau pathology (T) and neurodegeneration (N), halting progressive ATN pathology in a preclinical model | VANHERLE, Sarah; JANSSEN, Art; GUTIERREZ DE RAVE, Manu; JANSSEN, Bieke; LODDER, Chritica; BOTELLA LUCENA, Pablo; KESSELS, Sofie; HARDY, Jana; Vandeput, Eline; WANG, Yanyan; STANCU, Ilie Cosmin; Segal, Andrei; KLEINEWIETFELD, Markus; Voets , Thomas; BRONE, Bert; Poovathingal, Suresh; AGUIAR ALPIZAR, Yeranddy; DEWACHTER, Ilse | Journal Contribution | A1 |
| 2 | 2022 | Blood‑based Aβ42 increases in the earliest pre‑pathological stage before decreasing with progressive amyloid pathology in preclinical models and human subjects: opening new avenues for prevention | BOTELLA LUCENA, Pablo; VANHERLE, Sarah; LODDER, Chritica; GUTIERREZ DE RAVE, Manu; STANCU, Ilie Cosmin; LAMBRICHTS, Ivo; Vangheluwe, Riet; BRUFFAERTS, Rose; DEWACHTER, Ilse | Journal Contribution | A1 |
| 3 | 2022 | The NLRP3 inflammasome modulates tau pathology and neurodegeneration in a tauopathy model | STANCU, Ilie Cosmin; LODDER, Chritica; BOTELLA LUCENA, Pablo; VANHERLE, Sarah; GUTIERREZ DE RAVE, Manu; TERWEL, Dick; Bottelbergs, Astrid; DEWACHTER, Ilse | Journal Contribution | A1 |
| 4 | 2021 | CSF1R inhibition rescues tau pathology and neurodegeneration in an A/T/N model with combined AD pathologies, while preserving plaque associated microglia | LODDER, Chritica; Scheyltjens, I; STANCU, Ilie Cosmin; BOTELLA LUCENA, Pablo; GUTIERREZ DE RAVE, Manu; VANHERLE, Sarah; VANMIERLO, Tim; CREMERS, Niels; VANRUSSELT, Hannah; BRONE, Bert; Hanseeuw, B; Octave, JN; Bottelbergs, A; Movahedi, K; DEWACHTER, Ilse | Journal Contribution | A1 |
| 5 | 2019 | Tau Interacting Proteins: Gaining Insight into the Roles of Tau in Health and Disease | STANCU, Ilie Cosmin; Ferraiolo, Mattia; TERWEL, Dick; DEWACHTER, Ilse | Journal Contribution | A1 |
| 6 | 2019 | Sex-regulated gene dosage effect of PPARα on synaptic plasticity | Pierrot, Nathalie; Ris, Laurence; STANCU, Ilie Cosmin; Doshina, Anna; Ribeiro, Floriane; Tyteca, Donatienne; Baugé, Eric; Lalloyer, Fanny; Malong, Liza; Schakman, Olivier; Leroy, Karelle; Kienlen-Campard, Pascal; Gailly, Philippe; Brion, Jean-Pierre; DEWACHTER, Ilse; Staels, Bart; Octave, Jean-Noël | Journal Contribution | A1 |
| 7 | 2019 | Aggregated Tau activates NLRP3-ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo | STANCU, Ilie Cosmin; CREMERS, Niels; VANRUSSELT, Hannah; Couturier, J.; Vanoosthuyse, Alexandre; KESSELS, Sofie; LODDER, Chritica; BRONE, Bert; Huaux, F.; Octave, J. N.; TERWEL, Dick; DEWACHTER, Ilse | Journal Contribution | A1 |
| 8 | 2019 | Improvement of synaptic plasticity by pharmacological activation of RXR nuclear receptors is PPARα dependent | PIERROT, Nathalie; Ris, Laurence; STANCU, Ilie Cosmin; Leroy, Karelle; Kienlen-Campard, Pascal; Gailly, Philippe; Brion, Jean-Pierre; DEWACHTER, Ilse; Octave, Jean-Noël | Journal Contribution | M |
| 9 | 2018 | Synaptogyrin-3 Mediates Presynaptic Dysfunction Induced by Tau | McInnes, Joseph; Wierda, Keimpe; Snellinx, An; Bounti, Laura; Wang, Yu-Chun; STANCU, Ilie Cosmin; Apostolo, Nuno; Gevaert, Kris; DEWACHTER, Ilse; Spires-Jones, Tara L.; De Strooper, Bart; De Wit, Joris; Zhou, Lujia; Verstreken, Patrik | Journal Contribution | A1 |
| 10 | 2017 | Preclinical models of Alzheimer’s disease for identification and preclinical validation of therapeutic targets: from fine-tuning strategies for validated targets to new venues for therapy | Vasconcelos, Bruno; Bird, Matthew; STANCU, Ilie Cosmin; TERWEL, Dick; DEWACHTER, Ilse | Book Section | B2 |
| 11 | 2017 | Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo | Wang, Peng; Joberty, Gerard; Buist, Arjan; VANOOSTHUYSE, Alexandre; STANCU, Ilie Cosmin; Vasconcelos, Bruno; Pierrot, Nathalie; Faelth-Savitski, Maria; Kienlen-Campard, Pascal; Octave, Jean-Noël; Bantscheff, Marcus; Drewes, Gerard; Moechars, Diederik; DEWACHTER, Ilse | Journal Contribution | A1 |
| 12 | 2017 | [P4-037]: Identification of novel targets for inhibiting prion-like seeding and propagation of Tau pathology in vitro and in vivo | DEWACHTER, Ilse; STANCU, Ilie Cosmin; VANOOSTHUYSE, Alexandre; Buist, Arjan; Vasconcelos, Bruno; Wang, Peng; Kienlen-Campard, Pascal; Octave, Jean-Noël; Moechars, Diederik | Journal Contribution | M |
| 13 | 2016 | Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo | Vasconcelos, Bruno; STANCU, Ilie Cosmin; Buist, Arjan; Bird, Matthew; Wang, Peng; Van Kolen, Kristof; Verheyen, An; Kienlen-Campard, Pascal; Octave, Jean-Noël; Baatsen, Peter; Moechars, Diederik; DEWACHTER, Ilse; Oosterhuyse, Alexandre | Journal Contribution | A1 |
| 14 | 2016 | Activation of phagocytic activity in astrocytes by reduced expression of the inflammasome component ASC and its implication in a mouse model of Alzheimer disease | STANCU, Ilie Cosmin; Couturier, Julien; Schakman, Olivier; Pierrot, Nathalie; Huaux, François; Kienlen-Campard, Pascal; DEWACHTER, Ilse; Octave, Jean-Noël | Journal Contribution | A1 |
| 15 | 2016 | O5-04-01: Molecular mechanisms of Abeta-induced Tau-pathology: Analysis of cross-seeding of Abeta and Tau and its role in prion-like propagation of Tau-pathology in vitro and in vivo | Vasconcelos, Bruno; STANCU, Ilie Cosmin; Buist, Arjan; Bird, Matthew; Wang, Peng; VANOOSTHUYSE, Alexandre; Van Kolen, Kristof; VERHEYEN, Tim; Kienlen-Campard, Pascal; Octave, Jean-Noël; Baatsen, Peter; Moechars, Diederik; DEWACHTER, Ilse | Journal Contribution | M |
| 16 | 2016 | P3-072: Identification and Validation of TAU-Modifiers, Identified by Unbiased Genome Wide Approaches, Using AAV-Based Approaches in TAU Transgenic Mice | Wang, Peng; STANCU, Ilie Cosmin; Vasconcelos, Bruno; Bird, Matthew; VANOOSTHUYSE, Alexandre; Moechars, Diederik; DEWACHTER, Ilse | Journal Contribution | M |
| 17 | 2015 | Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice | STANCU, Ilie Cosmin; Vasconcelos, Bruno; Ris, Laurence; Wang, Peng; Villers, Agnès; PEERAER, Eve; Buist, Arjan; TERWEL, Dick; Baatsen, Peter; Oyelami, Tutu; Pierrot, Nathalie; Casteels, Cindy; Bormans, Guy; Kienlen-Campard, Pascal; Octave, Jean-Nöel; Moechars, Diederik; DEWACHTER, Ilse | Journal Contribution | A1 |
| 18 | 2015 | Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice | PEERAER, Eve; Bottelbergs, Astrid; Van Kolen, Kristof; STANCU, Ilie Cosmin; Vasconcelos, Bruno; Mahieu, Michel; Duytschaever, Hilde; Ver Donck, Luc; Torremans, An; Sluydts, Ellen; Van Acker, Nathalie; Kemp, John A; Mercken, Marc; Brunden, Kurt R; Trojanowski, John Q; DEWACHTER, Ilse; Lee, Virginia M Y; Moechars, Diederik | Journal Contribution | A1 |
| 19 | 2014 | Tauopathy contributes to synaptic and cognitive deficits in a murine model for Alzheimer's disease | STANCU, Ilie Cosmin; Ris, Laurence; Vasconcelos, Bruno; Marinangeli, Claudia; Goeminne, Leonie; Laporte, Vincent; Haylani, Laetitia E; Couturier, Julien; Schakman, Olivier; Gailly, Philippe; Pierrot, Nathalie; Kienlen-Campard, Pascal; Octave, Jean-Noël; DEWACHTER, Ilse | Journal Contribution | A1 |
| 20 | 2014 | Models of β-amyloid induced Tau-pathology: the long and "folded" road to understand the mechanism | STANCU, Ilie Cosmin; Vasconcelos, Bruno; TERWEL, Dick; DEWACHTER, Ilse | Journal Contribution | A1 |
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