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http://hdl.handle.net/1942/13528| Title: | ROLE OF NA+/K+ EXCHANGE AND ORGANIC-ACIDS IN BASE INDUCED HYPERPOLARIZATION OF RENAL PROXIMAL AMPHIBIAN TUBULE | Authors: | STEELS, Paul GRANITZER, Marita GRANITZER, Marita STEELS, Paul |
Issue Date: | 1991 | Publisher: | ELSEVIER SCIENCE BV ELSEVIER SCIENCE BV |
Source: | BIOCHIMICA ET BIOPHYSICA ACTA, 1066 (1), p. 111-114 BIOCHIMICA ET BIOPHYSICA ACTA, 1066(1). p. 111-114 |
Abstract: | Fast peritubular alkaline perturbations in Necturus renal proximal tubule evoke hyperpolarizations of the basolateral membrane. These voltage changes are partly due to an increase in basolateral K+-permeability. Additional role of the Na+/K+-ATPase and organic acids in generating these base induced hyperpolarizations (BIH) can be deduced from the reduction in BIH during low K+, high amiloride or omission of organic acids. Fast peritubular alkaline perturbations in Necturus renal proximal tubule evoke hyperpolarizations of the basolateral membrane. These voltage changes are partly due to an increase in basolateral K+-permeability. Additional role of the Na+/K+-ATPase and organic acids in generating these base induced hyperpolarizations (BIH) can be deduced from the reduction in BIH during low K+, high amiloride or omission of organic acids. |
Notes: | LIMBURGS UNIV CENTRUM,DEPT WNIFYSIOL,B-3610 DIEPENBEEK,BELGIUM. | Keywords: | Biochemistry & Molecular Biology; Biophysics;HYPERPOLARIZATION; PH EFFECT; SODIUM POTASSIUM ION EXCHANGE; ORGANIC ACID; BASOLATERAL MEMBRANE POTENTIAL; MEMBRANE POTENTIAL; PROXIMAL TUBULE; (NECTURUS KIDNEY);HYPERPOLARIZATION; PH EFFECT; SODIUM POTASSIUM ION EXCHANGE; ORGANIC ACID; BASOLATERAL MEMBRANE POTENTIAL; MEMBRANE POTENTIAL; PROXIMAL TUBULE; (NECTURUS KIDNEY) | Document URI: | http://hdl.handle.net/1942/3903 http://hdl.handle.net/1942/13528 |
ISSN: | 0005-2728 | e-ISSN: | 1879-2650 | ISI #: | A1991FW86900019 | Type: | Journal Contribution |
| Appears in Collections: | Research publications |
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