Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/40344
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dc.date.accessioned2023-06-08T13:11:00Z-
dc.date.available2023-06-08T13:11:00Z-
dc.date.issued2019-
dc.date.submitted2023-06-08T13:06:21Z-
dc.identifier.citationZenodo. 10.5281/zenodo.3564280 https://zenodo.org/record/3564280-
dc.identifier.urihttp://hdl.handle.net/1942/40344-
dc.description.abstractOpen data for a randomized clinical trial performed in onchocerciasis-endemic villages of the Logo health zone in Ituri province in the Democratic Republic of Congo where mass ivermectin administration had never been implemented. Ivermectin naïve, persons with epilepsy with Onchocerca volvulus infection were randomly allocated to receive ivermectin once, twice or thrice over a one year period of follow up. At the same time they were treated with the anti-epileptic drug phenobarbital. At baseline, information was collected on seizure semiology, seizure frequency, epilepsy risk factors, relevant medical history, previous AED and ivermectin use. The primary outcome was seizure freedom during the last four months of the 12-month follow up period.-
dc.description.sponsorshipNodding Syndrome: a trans-disciplinary approach to identify the cause and decrease the incidence of river epilepsy. European Commission. awardNumber:671055. https://doi.org/10.13039/501100000780-
dc.description.sponsorshipEuropean Research Council (ERC 671055)-
dc.description.sponsorshipVLIRUOS (Flemish University development aid)-
dc.language.isoen-
dc.publisherZenodo-
dc.subject.classificationTropical medicine-
dc.subject.otherIvermectin-
dc.subject.otheronchocerciasis-
dc.subject.otherepilepsy-
dc.subject.otherDemocratic Republic of Congo-
dc.subject.otherOnchocerca volvulus-
dc.subject.otherseizure-
dc.titleSingle versus multiple dose ivermectin regimen in onchocerciasis-infected persons with epilepsy treated with phenobarbital: a randomized clinical trial in the Democratic Republic of Congo-
dc.typeDataset-
local.bibliographicCitation.jcatDS-
dc.description.version1.0-
dc.rights.licenseCreative Commons Attribution 4.0 International (CC-BY-4.0)-
dc.identifier.doi10.5281/zenodo.3564280-
dc.identifier.urlhttps://zenodo.org/record/3564280-
dc.description.otherSupplementary Materials The following are available online at https://www.mdpi.com/2076-0817/9/3/205/s1, Table S1: Consort 2010 checklist; File S2: Clinical trial protocol; Table S3: Data analysis using a Zero-inflated Poisson regression model; Table S4: Seizure characteristics of participants at baseline and during the last four months of follow-up. Funding The study was funded by a grant from the European Research Council (ERC 671055) and VLIRUOS (Flemish University development aid). The study sponsors had no role in the design, execution, interpretation, or writing of the study.-
local.provider.typedatacite-
local.uhasselt.internationalyes-
local.contributor.datacreatorMandro, Michel-
local.contributor.datacreatorSiewe Fodjo, Joseph Nelson-
local.contributor.datacreatorDusabimana, Alfred-
local.contributor.datacreatorMukendi, Deby-
local.contributor.datacreatorHAESENDONCKX, Steven-
local.contributor.datacreatorLokonda, Richard-
local.contributor.datacreatorNakato, Swabra-
local.contributor.datacreatorNyisi, Francoise-
local.contributor.datacreatorAbhafule, Germain-
local.contributor.datacreatorWonya'Rossi, D-
local.contributor.datacreatorHotterbeekx, An-
local.contributor.datacreatorABRAMS, Steven-
local.contributor.datacreatorColebunders, Robert-
local.contributor.datacuratorMandro, Michel-
local.contributor.rightsholderMandro, Michel-
local.format.extent131.1 Kb-
local.format.mimetypesas7bdat-
local.contributororcid.datacreator0000-0002-2800-7816-
local.contributororcid.datacreator0000-0003-3544-1239-
local.contributororcid.datacreator0000-0003-2660-880X-
local.contributororcid.datacreator0000-0001-9229-5034-
local.contributororcid.datacreator0000-0001-8222-3686-
local.contributororcid.datacreator0000-0003-3356-4032-
local.contributororcid.datacreator0000-0001-7353-9304-
local.contributororcid.datacreator0000-0002-1919-1340-
local.contributororcid.datacurator0000-0002-2800-7816-
local.contributororcid.rightsholder0000-0002-2800-7816-
local.publication.doi10.3390/pathogens9030205-
local.contributingorg.datacreatorUniversity of Antwerp-
local.contributingorg.datacreatorHasselt University-
local.contributingorg.datacreatorUniversity of Kinshasa-
local.contributingorg.datacreatorCentre de Recherche en Maladies Tropicales de l’Ituri-
local.contributingorg.datacreatorProvincial Health Division Ituri, Ministry of Health-
local.contributingorg.datacreatorProgramme National de Lutte contre l’Onchocercose-
local.contributingorg.datacuratorUniversity of Antwerp-
local.contributingorg.rightsholderUniversity of Antwerp-
dc.rights.accessOpen Access-
item.contributorMandro, Michel-
item.contributorSiewe Fodjo, Joseph Nelson-
item.contributorDusabimana, Alfred-
item.contributorMukendi, Deby-
item.contributorHAESENDONCKX, Steven-
item.contributorLokonda, Richard-
item.contributorNakato, Swabra-
item.contributorNyisi, Francoise-
item.contributorAbhafule, Germain-
item.contributorWonya'Rossi, D-
item.contributorHotterbeekx, An-
item.contributorABRAMS, Steven-
item.contributorColebunders, Robert-
item.fullcitationMandro, Michel; Siewe Fodjo, Joseph Nelson; Dusabimana, Alfred; Mukendi, Deby; HAESENDONCKX, Steven; Lokonda, Richard; Nakato, Swabra; Nyisi, Francoise; Abhafule, Germain; Wonya'Rossi, D; Hotterbeekx, An; ABRAMS, Steven & Colebunders, Robert (2019) Single versus multiple dose ivermectin regimen in onchocerciasis-infected persons with epilepsy treated with phenobarbital: a randomized clinical trial in the Democratic Republic of Congo. Zenodo. 10.5281/zenodo.3564280 https://zenodo.org/record/3564280.-
item.fulltextNo Fulltext-
item.accessRightsClosed Access-
crisitem.license.codeCC-BY-4.0-
crisitem.license.nameCreative Commons Attribution 4.0 International (CC-BY-4.0)-
crisitem.discipline.code03023501-
crisitem.discipline.nameTropical medicine-
crisitem.discipline.pathMedical and health sciences > Clinical sciences > Tropical medicine > Tropical medicine-
crisitem.discipline.pathandcodeMedical and health sciences > Clinical sciences > Tropical medicine > Tropical medicine (03023501)-
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