Dataset: ABEL-FRET data for A2A Adenosine Receptor with analysis scripts - SI for Maslov et al. "ABEL-FRET bridges the timescale gap in single-molecule measurements of the structural dynamics in the A2A adenosine receptor"

Abstract

Supplementary data for "ABEL-FRET bridges the timescale gap in single-molecule measurements of the structural dynamics in the A2A adenosine receptor”, Maslov et al. https://doi.org/10.1038/s42004-026-01941-8 In this work, we employed single-molecule FRET (smFRET) in combination with Anti-Brownian Electrokinetic (ABEL) trapping to monitor conformational dynamics of untethered A2A adenosine receptors embedded in lipid nanodiscs. This repository contains:- Fluorescence burst data exported from BurstAnalyzer- Jupyter notebooks and Python scripts for data analysis- Numerical and graphical outputs- Final figure layouts used in the publication Corresponding authors: Michael Börsch Jena University Hospital, Single Molecule Microscopy Group, Jena, Germany E-mail: michael.boersch@med.uni-jena.de Thomas Gensch Institute of Biological Information Processing, Molecular and Cellular Physiology (IBI-1), Forschungszentrum Jülich GmbH, 52428, Jülich, Germany E-mail: t.gensch@fz-juelich.de