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http://hdl.handle.net/1942/5611
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DC Field | Value | Language |
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dc.contributor.author | VAN MIEGHEM, Walter | - |
dc.contributor.author | Tits, G. | - |
dc.contributor.author | DEMUYNCK, Koen | - |
dc.contributor.author | Lacquet, L. | - |
dc.contributor.author | Deneffe, G. | - |
dc.contributor.author | Tjandra-maga, T. | - |
dc.contributor.author | Demedts, M. | - |
dc.date.accessioned | 2007-12-20T16:00:25Z | - |
dc.date.available | 2007-12-20T16:00:25Z | - |
dc.date.issued | 1996 | - |
dc.identifier.citation | Annals of thoracic surgery, 61. p. 1083-1085 | - |
dc.identifier.uri | http://hdl.handle.net/1942/5611 | - |
dc.description.abstract | Background. Atrial fibrillation is a frequently occurring arrhythmia after thoracic operations. Preventive strategies for this complication have been extensively evaluated after cardiac operations. Methods. We performed a prospective, open randomized study, comparing intravenous verapamil and placebo in 199 patients after pneumonectomy or lobectomy at the University Hospital of Leuven. Verapamil was administered as a bolus of 10 mg over 2 minutes followed by a 30-minute infusion of 0.375 mg/min and then 0.125 mg/min for 3 days. The patients were continuously monitored in the postoperative intensive care unit. Results. Atrial fibrillation occurred in 15% of the patients receiving placebo and in 8% of the patients receiving verapamil (difference not significant). The verapamil infusion was interrupted in 9% of the patients because of bradycardia and in 14% because of hypotension. Conclusions. If tolerated, continuous intravenous verapamil infusion showed only a modest prophylactic efficacy for the occurrence of atrial fibrillation after lung operations. In the dose employed the verapamil infusion was accompanied with a high incidence of side effects necessitating interruption of the therapy. | - |
dc.language.iso | en | - |
dc.title | Verapamil as prophylactic treatment for atrial fibrillation after lung operations | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 1085 | - |
dc.identifier.spage | 1083 | - |
dc.identifier.volume | 61 | - |
dc.bibliographicCitation.oldjcat | - | |
dc.identifier.url | http://ats.ctsnetjournals.org/cgi/content/abstract/61/4/1083?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=1&title=Verapamil+as+prophylactic+treatment+&andorexacttitle=and&andorexacttitleabs=and&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT | - |
item.accessRights | Closed Access | - |
item.contributor | VAN MIEGHEM, Walter | - |
item.contributor | Tits, G. | - |
item.contributor | DEMUYNCK, Koen | - |
item.contributor | Lacquet, L. | - |
item.contributor | Deneffe, G. | - |
item.contributor | Tjandra-maga, T. | - |
item.contributor | Demedts, M. | - |
item.fullcitation | VAN MIEGHEM, Walter; Tits, G.; DEMUYNCK, Koen; Lacquet, L.; Deneffe, G.; Tjandra-maga, T. & Demedts, M. (1996) Verapamil as prophylactic treatment for atrial fibrillation after lung operations. In: Annals of thoracic surgery, 61. p. 1083-1085. | - |
item.fulltext | No Fulltext | - |
Appears in Collections: | Non-affiliated authors |
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