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| | Issue Date | Title | Contributor(s) | Type | Cat. |
| 21 | 2017 | Preclinical models of Alzheimer’s disease for identification and preclinical validation of therapeutic targets: from fine-tuning strategies for validated targets to new venues for therapy | Vasconcelos, Bruno; Bird, Matthew; STANCU, Ilie Cosmin; TERWEL, Dick; DEWACHTER, Ilse | Book Section | B2 |
| 2 | 2017 | [P4-037]: Identification of novel targets for inhibiting prion-like seeding and propagation of Tau pathology in vitro and in vivo | DEWACHTER, Ilse; STANCU, Ilie Cosmin; VANOOSTHUYSE, Alexandre; Buist, Arjan; Vasconcelos, Bruno; Wang, Peng; Kienlen-Campard, Pascal; Octave, Jean-Noël; Moechars, Diederik | Journal Contribution | M |
| 3 | 2017 | Presenilin 2-Dependent Maintenance of Mitochondrial Oxidative Capacity and Morphology | Contino, Sabrina; Porporato, Paolo E; Bird, Matthew; Marinangeli, Claudia; Opsomer, Rémi; Sonveaux, Pierre; Bontemps, Françoise; DEWACHTER, Ilse; Octave, Jean-Noël; Bertrand, Luc; Stanga, Serena; Kienlen-Campard, Pascal | Journal Contribution | A1 |
| 4 | 2017 | Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission | Doshina, Anna; Gourgue, Florian; Onizuka, Michiho; Opsomer, Remi; Wang, Peng; Ando, Kunie; Tasiaux, Bernadette; DEWACHTER, Ilse; Kienlen-Campard, Pascal; Brion, Jean-Pierre; Gailly, Philippe; Octave, Jean-Noël; Pierrot, Nathalie | Journal Contribution | A2 |
| 5 | 2017 | Tau association with synaptic vesicles causes presynaptic dysfunction | Zhou, Lujia; McInnes, Joseph; Weirda, Keimpe; Holt, Matthew; Herrmann, Abigail G.; Jackson, Rosemary J.; Wang, Yu-Chun; Swerts, Jef; Beyens, Jelle; Miskiewicz, Katarzyna; Vilain, Sven; DEWACHTER, Ilse; Moechars, Diederik; De Strooper, Bart; Spires-Jones, Tara L.; De Wit, Joris; Verstreken, Patrik | Journal Contribution | A1 |
| 6 | 2017 | What is the evidence that tau pathology spreads through prion-like propagation? | Mudher, Amrit; Colin, Morvane; Dujardin, Simon; Medina, Miguel; DEWACHTER, Ilse; Naini, Seyedeh Maryam Alavi; Mandelkow, Eva-Maria; Mandelkow, Eckhard; Buee, Luc; Goedert, Michel; Brion, Jean-Pierre | Journal Contribution | A1 |
| 7 | 2017 | Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo | Wang, Peng; Joberty, Gerard; Buist, Arjan; VANOOSTHUYSE, Alexandre; STANCU, Ilie Cosmin; Vasconcelos, Bruno; Pierrot, Nathalie; Faelth-Savitski, Maria; Kienlen-Campard, Pascal; Octave, Jean-Noël; Bantscheff, Marcus; Drewes, Gerard; Moechars, Diederik; DEWACHTER, Ilse | Journal Contribution | A1 |
| 48 | 2016 | Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo | Vasconcelos, Bruno; STANCU, Ilie Cosmin; Buist, Arjan; Bird, Matthew; Wang, Peng; Van Kolen, Kristof; Verheyen, An; Kienlen-Campard, Pascal; Octave, Jean-Noël; Baatsen, Peter; Moechars, Diederik; DEWACHTER, Ilse; Oosterhuyse, Alexandre | Journal Contribution | A1 |
| 49 | 2016 | Activation of phagocytic activity in astrocytes by reduced expression of the inflammasome component ASC and its implication in a mouse model of Alzheimer disease | STANCU, Ilie Cosmin; Couturier, Julien; Schakman, Olivier; Pierrot, Nathalie; Huaux, François; Kienlen-Campard, Pascal; DEWACHTER, Ilse; Octave, Jean-Noël | Journal Contribution | A1 |
| 50 | 2016 | P3-072: Identification and Validation of TAU-Modifiers, Identified by Unbiased Genome Wide Approaches, Using AAV-Based Approaches in TAU Transgenic Mice | Wang, Peng; STANCU, Ilie Cosmin; Vasconcelos, Bruno; Bird, Matthew; VANOOSTHUYSE, Alexandre; Moechars, Diederik; DEWACHTER, Ilse | Journal Contribution | M |
| 51 | 2016 | Glycines from the APP GXXXG/GXXXA Transmembrane Motifs Promote Formation of Pathogenic Aβ Oligomers in Cells | Decock, Marie; Stanga, Serena; Octave, Jean-Noël; DEWACHTER, Ilse; Smith, Steven O; Constantinescu, Stefan N; Kienlen-Campard, Pascal | Journal Contribution | A1 |
| 52 | 2016 | APP-dependent glial cell line-derived neurotrophic factor gene expression drives neuromuscular junction formation | Stanga, Serena; Zanou, Nadège; Audouard, Emilie; Tasiaux, Bernadette; Contino, Sabrina; Vandermeulen, Gaëlle; René, Frédérique; Loeffler, Jean-Philippe; Clotman, Frédéric; Gailly, Philippe; DEWACHTER, Ilse; Octave, Jean-Noël; Kienlen-Campard, Pascal | Journal Contribution | A1 |
| 53 | 2016 | O5-04-01: Molecular mechanisms of Abeta-induced Tau-pathology: Analysis of cross-seeding of Abeta and Tau and its role in prion-like propagation of Tau-pathology in vitro and in vivo | Vasconcelos, Bruno; STANCU, Ilie Cosmin; Buist, Arjan; Bird, Matthew; Wang, Peng; VANOOSTHUYSE, Alexandre; Van Kolen, Kristof; VERHEYEN, Tim; Kienlen-Campard, Pascal; Octave, Jean-Noël; Baatsen, Peter; Moechars, Diederik; DEWACHTER, Ilse | Journal Contribution | M |
| 54 | 2015 | Characterization of Pterocarpus erinaceus kino extract and its gamma-secretase inhibitory properties | Hage, Salim; Stanga, Serena; Marinangeli, Claudia; Octave, Jean-Noël; DEWACHTER, Ilse; Quetin-Leclercq, Joëlle; Kienlen-Campard, Pascal | Journal Contribution | A1 |
| 55 | 2015 | Presenilin transmembrane domain 8 conserved AXXXAXXXG motifs are required for the activity of the γ-secretase complex | Marinangeli, Claudia; Tasiaux, Bernadette; Opsomer, Rémi; Hage, Salim; Sodero, Alejandro O; DEWACHTER, Ilse; Octave, Jean Noël; Smith, Steven O; Constantinescu, Stefan N; Kienlen-Campard, Pascal | Journal Contribution | A1 |
| 56 | 2015 | Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice | PEERAER, Eve; Bottelbergs, Astrid; Van Kolen, Kristof; STANCU, Ilie Cosmin; Vasconcelos, Bruno; Mahieu, Michel; Duytschaever, Hilde; Ver Donck, Luc; Torremans, An; Sluydts, Ellen; Van Acker, Nathalie; Kemp, John A; Mercken, Marc; Brunden, Kurt R; Trojanowski, John Q; DEWACHTER, Ilse; Lee, Virginia M Y; Moechars, Diederik | Journal Contribution | A1 |
| 57 | 2015 | Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing | Decock, Marie; El Haylani, Laetitia; Stanga, Serena; DEWACHTER, Ilse; Octave, Jean-Noël; Smith, Steven O; Constantinescu, Stefan N; Kienlen-Campard, Pascal | Journal Contribution | A1 |
| 58 | 2015 | Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice | STANCU, Ilie Cosmin; Vasconcelos, Bruno; Ris, Laurence; Wang, Peng; Villers, Agnès; PEERAER, Eve; Buist, Arjan; TERWEL, Dick; Baatsen, Peter; Oyelami, Tutu; Pierrot, Nathalie; Casteels, Cindy; Bormans, Guy; Kienlen-Campard, Pascal; Octave, Jean-Nöel; Moechars, Diederik; DEWACHTER, Ilse | Journal Contribution | A1 |
| 59 | 2014 | Tauopathy contributes to synaptic and cognitive deficits in a murine model for Alzheimer's disease | STANCU, Ilie Cosmin; Ris, Laurence; Vasconcelos, Bruno; Marinangeli, Claudia; Goeminne, Leonie; Laporte, Vincent; Haylani, Laetitia E; Couturier, Julien; Schakman, Olivier; Gailly, Philippe; Pierrot, Nathalie; Kienlen-Campard, Pascal; Octave, Jean-Noël; DEWACHTER, Ilse | Journal Contribution | A1 |
| 60 | 2014 | P1-033: Amyloid-induced tauopathy contributes to synaptic and cognitive deficits in a transgenic model for Alzheimer's disease | STANCU, Ilie Cosmin; Ris, Laurence; Vasconcelos, Bruno; Marinangeli, Claudia; Goeminne, Léonie; Laporte, Vincent; Haylani, Laetitia El; Couturier, Julien; Schakman, Olivier; Gailly, Philippe; Pierrot, Nathalie; Kienlen-Campard, Pascal; Octave, Jean-Noël; DEWACHTER, Ilse | Journal Contribution | M |
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