PAES, Dean

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Full Name
PAES, Dean
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dean.paes@uhasselt.be
 
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Publications

Results 1-15 of 15 (Search time: 0.008 seconds).

Issue DateTitleContributor(s)TypeCat.
12024Beta-amyloid interacts with and activates the long-form phosphodiesterase PDE4D5 in neuronal cells to reduce cAMP availabilitySin, Yuan Yan; Cameron, Ryan T.; SCHEPERS, Melissa; Macleod, Ruth; Wright, Tom A.; PAES, Dean; van den Hove, Daniel; WILLEMS, Emily; Prickaerts, Jos; Blair, Connor M.; VANMIERLO, Tim; Baillie, George S.Journal ContributionA1
22023Picking the best isoform: PDE4D isoforms as therapeutic targets in Alzheimer's diseasePAES, DeanTheses and DissertationsT1
32023Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-beta pathologyPAES, Dean; SCHEPERS, Melissa; WILLEMS, Emily; ROMBAUT, Ben; TIANE, Assia; Solomina, Yevgeniya; Tibbo, Amy; Blair, Connor; Kyurkchieva, Elka; Baillie, George S.; Ricciarelli, Roberta; Brullo, Chiara; Fedele, Ernesto; Bruno, Olga; van den Hove, Daniel; VANMIERLO, Tim; Prickaerts, JosJournal ContributionA1
42023Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosisSCHEPERS, Melissa; PAES, Dean; TIANE, Assia; ROMBAUT, Ben; PICCART, Elisabeth; VAN VEGGEL, Lieve; GERVOIS, Pascal; Brullo, Chiara; Bruno, Olga; Fedele, Ernesto; Ricciarelli, Roberta; Ffrench-Constant, Charles; Bechler, Marie E.; Schaik, Pauline van; WOLFS, Esther; LAMBRICHTS, Ivo; Baron, Wia; LEFEVERE, Evy; Wasner, Kobi; Gruenewald, Anne; Verfaillie, Catherine; Wieringa, Paul; Prickaerts, Jos; BROUX, Bieke; BAETEN, Paulien; HELLINGS, Niels; VANMIERLO, TimJournal ContributionA1
52023Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosisVANMIERLO, Tim; SCHEPERS, Melissa; PAES, Dean; TIANE, Assia; ROMBAUT, Ben; PICCART, Elisabeth; VAN VEGGEL, Lieve; GERVOIS, Pascal; WOLFS, Esther; LAMBRICHTS, Ivo; Brullo, C.; Bruno, O.; Fidele, E.; Ricciarelli, R.; Ffrench-Constant, C.; Bechler, M. E.; van Schaik, P.; Baron, W.; Lefevere , E.; Wasner, K.; Grunewald, A.; Verfaillie, C.; BAETEN, Paulien; BROUX, Bieke; Wieringa, P.; HELLINGS, Niels; Prickaerts, J.Journal ContributionM
62023PDE4B as a key regulator of out of control microgliaROMBAUT, Ben; KESSELS, Sofie; TRIPPAERS, Chloe; SCHEPERS, Melissa; TIANE, Assia; PAES, Dean; KOULOUSAKIS, Philippos; WILLEMS, Emily; van den Hove, D.; Prickaerts, J.; BRONE, Bert; VANMIERLO, TimJournal ContributionM
72022Computational investigation of the dynamic control of cAMP signaling by PDE4 isoform typesPAES, Dean; Hermans, Sammy; van den Hove, Daniel; VANMIERLO, Tim; Prickaerts, Jos; Carlier, AurelieJournal ContributionA1
82021The Molecular Biology of Phosphodiesterase 4 Enzymes as Pharmacological Targets: An Interplay of Isoforms, Conformational States, and InhibitorsPAES, Dean; SCHEPERS, Melissa; ROMBAUT, Ben; van den Hove, Daniel; VANMIERLO, Tim; Prickaerts, Jos; Michel, MartinJournal ContributionA1
92021Pharmacological inhibition of phosphodiesterase 7 enhances consolidation processes of spatial memoryMcQuown, Susan; PAES, Dean; Baumgartel, Karsten; Prickaerts, Jos; Peters, MarcoJournal ContributionA1
102021Increased isoform-specific phosphodiesterase 4D expression is associated with pathology and cognitive impairment in Alzheimer’s diseasePAES, Dean; Lardenoije, Roy; CAROLLO, Riccardo; Roubroeks, Janou A. Y.; SCHEPERS, Melissa; Coleman, Paul; Mastroeni, Diego; Delvaux, Elaine; Pishva, Ehsan; Lunnon, Katie; VANMIERLO, Tim; van den Hove, Daniel; Prickaerts, JosJournal ContributionA1
112021PDE inhibition in distinct cell types to reclaim the balance of synaptic plasticityROMBAUT, Ben; KESSELS, Sofie; SCHEPERS, Melissa; TIANE, Assia; PAES, Dean; Solomina, Yevgeniya; PICCART, Elisabeth; van den Hove, Daniel; BRONE, Bert; Prickaerts, Jos; VANMIERLO, TimJournal ContributionA1
122019Relieving the epigenetic blockade in progressive multiple sclerosis - making remyelination accessible againTIANE, Assia; SCHEPERS, Melissa; PAES, Dean; Prickaerts, J.; van den Hove, D.; HELLINGS, Niels; VANMIERLO, TimJournal ContributionM
132019Phosphodiesterase 4D inhibition boosts remyelination in multiple sclerosisSCHEPERS, Melissa; Bruno, O.; PAES, Dean; TIANE, Assia; Brullo, C.; HOUBEN, Els; Prickaerts, J.; VANMIERLO, Tim; HELLINGS, NielsJournal ContributionM
142019Phosphodiesterase Type 4 Inhibition in CNS DiseasesBlokland, A; Heckman, P; VANMIERLO, Tim; Schreiber, R; PAES, Dean; Prickaerts, JJournal ContributionA1
152019Targeting Phosphodiesterases-Towards a Tailor-Made Approach in Multiple Sclerosis TreatmentSCHEPERS, Melissa; TIANE, Assia; PAES, Dean; SANCHEZ, Selien; ROMBAUT, Ben; PICCART, Elisabeth; Rutten, Bart P. F.; BRONE, Bert; HELLINGS, Niels; Prickaerts, Jos; VANMIERLO, TimJournal ContributionA1