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Title: | Insights in the autoimmunity of myasthenia gravis | Authors: | DE BAETS, Marc | Issue Date: | 2010 | Publisher: | TAYLOR & FRANCIS LTD | Source: | AUTOIMMUNITY, 43 (5-6). p. 341-343 | Abstract: | Myasthenia gravis is a prototype anti-receptor autoimmune disease. Antibodies against proteins at the neuromuscular junction cause a defect in the signal transmission from nerve terminal to the damaged postsynaptic membrane. This issue of Autoimmunity reviews the mechanisms that lead to the destruction of the neuromuscular junction and the role of the thymus in myasthenia gravis and its animal models. In addition, this issue explores recent advances in diagnosis and treatment of this disease. | Notes: | [De Baets, Marc H.] Univ Maastricht, Div Neurosci, Sch Mental Hlth & Neurosci, Neuroimmunol Grp,Dept Neurosci, NL-6200 MD Maastricht, Netherlands. [De Baets, Marc H.] Hasselt Univ, Biomed Res Inst BIOMED, Neuroimmunol Grp, Diepenbeek, Belgium. m.debaets@maastrichtuniversity.nl | Keywords: | Myasthenia gravis; autoimmunity; acetylcholine receptor; muscle-specific tyrosine kinase; neuromuscular;Myasthenia gravis; autoimmunity; acetylcholine receptor; muscle-specific tyrosine kinase; neuromuscular | Document URI: | http://hdl.handle.net/1942/11216 | ISSN: | 0891-6934 | e-ISSN: | 1607-842X | DOI: | 10.3109/08916931003592307 | ISI #: | 000281961100001 | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2011 |
Appears in Collections: | Research publications |
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