Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/12036
Title: EFFECT OF A PREPREGNANCY PERTUSSIS BOOSTER DOSE ON MATERNAL ANTIBODY TITERS IN YOUNG INFANTS
Authors: Leuridan, Elke
HENS, Niel 
Peeters, Natasja
de Witte, Liene
Van der Meeren, Olivier
Van Damme, Pierre
Issue Date: 2011
Publisher: LIPPINCOTT WILLIAMS & WILKINS
Source: PEDIATRIC INFECTIOUS DISEASE JOURNAL, 30(7). p. 608-610
Abstract: To examine the influence of a pertussis booster vaccination on the transfer of maternal antibodies, 24 nonpregnant women received a tetanus, diphtheria, acellular pertussis booster vaccine between 2 consecutive pregnancies. Blood was drawn from mothers and off-spring. Efficient transplacental antibody transfer and significantly higher antibody titers against 3 pertussis antigens were observed in cord blood and in blood of 1-month-old infants born after a maternal booster vaccination compared with results in their siblings born before the booster administration.
Notes: [Leuridan, Elke; Peeters, Natasja; de Witte, Liene; Van Damme, Pierre] Univ Antwerp, Ctr Evaluat Vaccinat, Vaccine & Infect Dis Inst, WHO Collaborating Ctr Control & Prevent Infect Di, B-2020 Antwerp, Belgium. [Hens, Niel] Univ Antwerp, Vaccine & Infect Dis Inst, CHERMID, Fac Med, B-2020 Antwerp, Belgium. [Hens, Niel] Univ Hasselt, Hasselt, Belgium. [Van der Meeren, Olivier] GlaxoSmithKline Biol, Rixensart, Belgium.
Keywords: neonatal pertussis; maternal antibodies; booster vaccination
Document URI: http://hdl.handle.net/1942/12036
ISSN: 0891-3668
e-ISSN: 1532-0987
DOI: 10.1097/INF.0b013e3182093814
ISI #: 000291675100020
Category: A1
Type: Journal Contribution
Validations: ecoom 2012
Appears in Collections:Research publications

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