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http://hdl.handle.net/1942/12036| Title: | EFFECT OF A PREPREGNANCY PERTUSSIS BOOSTER DOSE ON MATERNAL ANTIBODY TITERS IN YOUNG INFANTS | Authors: | Leuridan, Elke HENS, Niel Peeters, Natasja de Witte, Liene Van der Meeren, Olivier Van Damme, Pierre |
Issue Date: | 2011 | Publisher: | LIPPINCOTT WILLIAMS & WILKINS | Source: | PEDIATRIC INFECTIOUS DISEASE JOURNAL, 30(7). p. 608-610 | Abstract: | To examine the influence of a pertussis booster vaccination on the transfer of maternal antibodies, 24 nonpregnant women received a tetanus, diphtheria, acellular pertussis booster vaccine between 2 consecutive pregnancies. Blood was drawn from mothers and off-spring. Efficient transplacental antibody transfer and significantly higher antibody titers against 3 pertussis antigens were observed in cord blood and in blood of 1-month-old infants born after a maternal booster vaccination compared with results in their siblings born before the booster administration. | Notes: | [Leuridan, Elke; Peeters, Natasja; de Witte, Liene; Van Damme, Pierre] Univ Antwerp, Ctr Evaluat Vaccinat, Vaccine & Infect Dis Inst, WHO Collaborating Ctr Control & Prevent Infect Di, B-2020 Antwerp, Belgium. [Hens, Niel] Univ Antwerp, Vaccine & Infect Dis Inst, CHERMID, Fac Med, B-2020 Antwerp, Belgium. [Hens, Niel] Univ Hasselt, Hasselt, Belgium. [Van der Meeren, Olivier] GlaxoSmithKline Biol, Rixensart, Belgium. | Keywords: | neonatal pertussis; maternal antibodies; booster vaccination | Document URI: | http://hdl.handle.net/1942/12036 | ISSN: | 0891-3668 | e-ISSN: | 1532-0987 | DOI: | 10.1097/INF.0b013e3182093814 | ISI #: | 000291675100020 | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2012 |
| Appears in Collections: | Research publications |
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