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Title: Dynamics of HPV vaccination initiation in Flanders (Belgium) 2007-2009: a Cox regression model
Authors: Lefevere, Eva
HENS, Niel 
De Smet, Frank
Van Damme, Pierre
Issue Date: 2011
Abstract: Background: We investigated dynamic patterns and predictors of HPV vaccination initiation in Flanders (Belgium) by girls aged 12 to 18, between 2007 and 2009, the period immediately after the introduction of the HPV vaccines on the Belgian market. During this period the initiative for vaccination was taken by the girl, her family or the general practitioner/pediatrician/gynecologist. Methods: We used a Cox regression model with time constant and time varying predictors to model hazard rates of HPV vaccination initiation. The sample existed of 117,151 female members of the National Alliance of Christian Mutualities, the largest sickness fund in Flanders. Results: The study showed that the hazard of HPV vaccination initiation was higher (1) for older girls, (2) for girls with a more favorable socio-economic background, (3) under more generous reimbursement regimes (with this effect being more pronounced for girls with weak socioeconomic backgrounds), (4) for girls that were informed personally about the reimbursement rules. Conclusions: When the initiative for HPV vaccination lies with the girls, their families or the physicians (no organized setting) the uptake of the vaccines is affected by both individual and organizational factors.
Notes: [Lefevere, E] Univ Antwerp, Herman Deleeck Ctr Social Policy, B-2000 Antwerp, Belgium [Lefevere, E] Res Fdn Flanders, B-1000 Brussels, Belgium [Hens, N] Hasselt Univ, Ctr Stat CENSTAT, B-3590 Diepenbeek, Belgium [Hens, N] Univ Antwerp, CHERMID, B-2610 Antwerp, Belgium [De Smet, F] Natl Alliance Christian Mutual, Med Management Dept, B-1031 Brussels, Belgium [De Smet, F] Catholic Univ Leuven, Dept Occupat Environm & Insurance Med, B-3000 Louvain, Belgium [Van Damme, P] Univ Antwerp, Vaccine & Infect Dis Inst VAXINFECTIO, B-2610 Antwerp, Belgium [Van Damme, P] Univ Antwerp, Ctr Evaluat Vaccinat, B-2610 Antwerp, Belgium
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e-ISSN: 1471-2458
DOI: 10.1186/1471-2458-11-470
ISI #: 000292166900001
Category: A1
Type: Journal Contribution
Validations: ecoom 2012
Appears in Collections:Research publications

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