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Title: | Next generation functional proteomics in non-model plants: A survey on techniques and applications for the analysis of protein complexes and post-translational modifications | Authors: | Remmerie, Noor De Vijlder, Thomas Laukens, Kris Thanh Hai Dang Lemiere, Filip Mertens, Inge VALKENBORG, Dirk Blust, Ronny Witters, Erwin |
Issue Date: | 2011 | Publisher: | PERGAMON-ELSEVIER SCIENCE LTD | Source: | PHYTOCHEMISTRY, 72(10). p. 1192-1218 | Abstract: | The congruent development of computational technology, bioinformatics and analytical instrumentation makes proteomics ready for the next leap. Present-day state of the art proteomics grew from a descriptive method towards a full stake holder in systems biology. High throughput and genome wide studies are now made at the functional level. These include quantitative aspects, functional aspects with respect to protein interactions as well as post translational modifications and advanced computational methods that aid in predicting protein function and mapping these functionalities across the species border. In this review an overview is given of the current status of these aspects in plant studies with special attention to non-genomic model plants. (C) 2011 Elsevier Ltd. All rights reserved. | Notes: | [Remmerie, N; De Vijlder, T; Laukens, K; Lemiere, F; Witters, E] Univ Antwerp, Ctr Prote, B-2020 Antwerp, Belgium [Remmerie, N; De Vijlder, T] Univ Antwerp, Lab Plant Growth & Dev, Dept Biol, B-2020 Antwerp, Belgium [Laukens, K; Dang, TH] Univ Antwerp, Intelligent Syst Lab, Dept Math & Comp Sci, B-2020 Antwerp, Belgium [Lemiere, F] Univ Antwerp, Nucleoside Res & Mass Spectrometry Unit, Dept Chem, B-2020 Antwerp, Belgium [Mertens, I; Valkenborg, D; Witters, E] Vlaamse Instelling Technol Onderzoek, B-2400 Mol, Belgium [Valkenborg, D] Univ Hasselt, Interuniv Inst Biostat & Stat Bioinformat, B-3590 Diepenbeek, Belgium [Blust, R; Witters, E] Univ Antwerp, Lab Ecophysiol Biochem & Toxicol, Dept Biol, B-2020 Antwerp, Belgium | Keywords: | Cross-species; Protein-protein interactions; Post translational modifications; Computational methods | Document URI: | http://hdl.handle.net/1942/12126 | ISSN: | 0031-9422 | e-ISSN: | 1873-3700 | DOI: | 10.1016/j.phytochem.2011.01.003 | ISI #: | 000292536100021 | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2012 |
Appears in Collections: | Research publications |
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