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|Title:||Towards a multi-sensor system for the evaluation of aseptic processes employing hydrogen peroxide vapour (H(2)O(2))||Authors:||Reisert, Steffen
Schoening, Michael J.
|Issue Date:||2011||Publisher:||WILEY-BLACKWELL||Source:||PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE, 208(6). p. 1351-1356||Abstract:||The presented work focuses on the development of a multi-sensor system for the evaluation of aseptic processes employing hydrogen peroxide vapour. In a first step, selected commercially available gas sensors have been investigated on cross-sensitivity towards hydrogen peroxide vapour and humidity. An MOX (TGS 816, Figaro) and a solid-electrolyte gas sensor (SO-A0-250, Electrovac) (lambda-probe) have shown good characteristics in terms of sensitivity towards HPV, considering also reproducibility, long-term drift and stability. Further, the sterilization effect of HPV has been investigated by means of the microbial reduction test. A correlation between the microbial reduction of Bacillus subtilis spores and the sensor response in hydrogen peroxide atmosphere has been established. Based on this correlation the microbial reduction may be estimated by means of the sensor output over a wide range of parameters. (C) 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim||Notes:||[Reisert, S; Nather, N; Schoning, MJ] Aachen Univ Appl Sci, Inst Nano & Biotechnol, D-52428 Julich, Germany [Geissler, H; Florke, R] SIG Combibloc Syst GmbH, D-52441 Linnich, Germany [Wagner, P] Hasselt Univ, Inst Mat Res, B-3590 Diepenbeek, Belgium firstname.lastname@example.org||Keywords:||aseptic processes; Bacillus subtilis; hydrogen peroxide; multi-sensor;aseptic processes; Bacillus subtilis; hydrogen peroxide; multi-sensor||Document URI:||http://hdl.handle.net/1942/12129||ISSN:||1862-6300||e-ISSN:||1862-6319||DOI:||10.1002/pssa.201001138||ISI #:||000292945800024||Category:||A1||Type:||Journal Contribution||Validations:||ecoom 2012|
|Appears in Collections:||Research publications|
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