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|Title:||Impact of guideline implementation by a fracture nurse on subsequent fractures and mortality in patients presenting with non-vertebral fractures||Authors:||Huntjens, Kirsten M. B.
van Geel, Tineke C. M.
van den Bergh, Joop
Brink, Peter R. G.
van Helden, Svenhjalmar
|Issue Date:||2011||Publisher:||ELSEVIER SCI LTD||Source:||INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 42. p. S39-S43||Abstract:||Introduction: Systematic implementation of guidelines in patients presenting with a fracture increases identification of patients at high risk for subsequent fractures and contributes to a decreased fracture risk. Its effect on prevention of subsequent fractures and on mortality has not been documented. The aim of this study was to determine the impact of the implementation of specific guidelines on the risk of subsequent fractures and mortality in patients presenting with a non-vertebral fracture (NVF). Patients and methods: Before-after impact analysis in consecutive patients older than 50 years who were admitted to the hospital with a NVF during 2 periods: pre-intervention group (n = 1,920, enrolled in 1999-2001) and intervention group (n = 1,335, enrolled in 2004-2006). The intervention consisted of a dedicated fracture nurse who systematically offered fracture risk evaluation and treatment according to available guidelines. The 2-year absolute risk (AR) and hazard ratio's (HR, with 95% confidence interval (CI)) of subsequent NVFs and mortality were analysed between both groups after adjustment for age, sex and baseline fracture location by multivariable Cox regression and by intention-to-treat. Results: The AR of subsequent fracture was 9.9% before and 6.7% after intervention, indicating a decrease of 35% in the risk of subsequent fracture (HR 0.65; CI: 0.51-0.84, after adjustment for age, sex and baseline fracture location) and 17.9% and 11.6%, respectively, for subsequent mortality, indicating a decrease of 33% in the risk of subsequent mortality (HR: 0.67; CI: 0.55-0.81, after adjustment for age, sex and baseline fracture location). Conclusions: Systematic implementation of guidelines for fracture prevention by a dedicated fracture nurse immediately after a NVF is associated with a significant reduction of the 2-year risk of subsequent NVF and mortality. (C) 2011 Elsevier Ltd. All rights reserved.||Notes:||[Huntjens, KMB; Brink, PRG; van Helden, S] Maastricht Univ, Med Ctr, Dept Trauma Surg, NL-6202 AZ Maastricht, Netherlands. [Huntjens, KMB; van Geel, TCM; Geusens, PP; Winkens, B; van Helden, S] Caphri Sch Publ Hlth & Primary Care, Maastricht, Netherlands. [van Geel, TCM] Maastricht Univ, Med Ctr, Dept Gen Practice, NL-6202 AZ Maastricht, Netherlands. [Geusens, PP; van den Bergh, J] Maastricht Univ, Med Ctr, Dept Internal Med, NL-6202 AZ Maastricht, Netherlands. [Geusens, PP] Hasselt Univ, Biomed Res Inst, Diepenbeek, Belgium. [Winkens, B] Maastricht Univ, Med Ctr, Dept Methodol & Stat, NL-6202 AZ Maastricht, Netherlands. [Willems, P] Maastricht Univ, Med Ctr, Dept Orthopaed Surg, NL-6202 AZ Maastricht, Netherlands. [van den Bergh, J] VieCuri Hosp Venlo, Dept Internal Med, Venlo, Netherlands. email@example.com||Keywords:||Fractures; Mortality; Osteoporosis; Implementation; Guidelines;Fractures; Mortality; Osteoporosis; Implementation; Guidelines||Document URI:||http://hdl.handle.net/1942/12305||ISSN:||0020-1383||e-ISSN:||1879-0267||ISI #:||000295212400008||Category:||A1||Type:||Journal Contribution||Validations:||ecoom 2012|
|Appears in Collections:||Research publications|
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