Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/13669
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dc.contributor.authorVerdonck, K.-
dc.contributor.authorGonzález, E.-
dc.contributor.authorSCHROOTEN, Ward-
dc.contributor.authorVanham, G.-
dc.contributor.authorGotuzzo, E.-
dc.date.accessioned2012-05-22T11:58:44Z-
dc.date.available2012-05-22T11:58:44Z-
dc.date.issued2007-
dc.identifier.citationEPIDEMIOLOGY AND INFECTION, 136 (8), p. 1076-1083-
dc.identifier.issn0950-2688-
dc.identifier.urihttp://hdl.handle.net/1942/13669-
dc.description.abstractSUMMARY:The purpose of this study was to assess the association between human T-lymphotropic virus 1 (HTLV-1) and a lifetime history of active tuberculosis (TB) among relatives of HTLV-1-infected patients. We reviewed clinical charts of all relatives of HTLV-1-infected index cases who attended our institute in Lima from 1990-2004. The data of 1233 relatives was analysed; 394 (32.0%) were HTLV-1 positive. Eighty-one subjects (6.6%) had a history of active TB, including 45/394 (11.4%) HTLV-1-positive and 36/839 (4.3%) HTLV-1-negative relatives (P<0.001). On multivariate analysis, three factors were associated with TB history: HTLV-1 infection (adjusted OR 2.5, 95% CI 1.6-3.9), age (adjusted OR 1.3, 95% CI 1.1-1.5 per 10-year age increase) and relation to the index case (adjusted OR 2.6, 95% CI 1.3-5.1, for siblings vs. spouses of index cases). In conclusion, HTLV-1 infection may increase the susceptibility to active TB. In populations where both infections are frequent, such an association could affect the dynamics of TB.-
dc.language.isoen-
dc.titleHTLV-1 infection is associated with a history of active tuberculosis among family members of HTLV-1-infected patients in Peru-
dc.typeJournal Contribution-
dc.identifier.epage1083-
dc.identifier.issue8-
dc.identifier.spage1076-
dc.identifier.volume136-
local.format.pages1-8-
local.bibliographicCitation.jcatA1-
local.type.refereedRefereed-
local.type.specifiedArticle-
dc.bibliographicCitation.oldjcatA2-
dc.identifier.doi10.1017/S0950268807009521-
dc.identifier.isi000259748200008-
item.fulltextNo Fulltext-
item.contributorVerdonck, K.-
item.contributorGonzález, E.-
item.contributorSCHROOTEN, Ward-
item.contributorVanham, G.-
item.contributorGotuzzo, E.-
item.fullcitationVerdonck, K.; González, E.; SCHROOTEN, Ward; Vanham, G. & Gotuzzo, E. (2007) HTLV-1 infection is associated with a history of active tuberculosis among family members of HTLV-1-infected patients in Peru. In: EPIDEMIOLOGY AND INFECTION, 136 (8), p. 1076-1083.-
item.accessRightsClosed Access-
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