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http://hdl.handle.net/1942/13669
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DC Field | Value | Language |
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dc.contributor.author | Verdonck, K. | - |
dc.contributor.author | González, E. | - |
dc.contributor.author | SCHROOTEN, Ward | - |
dc.contributor.author | Vanham, G. | - |
dc.contributor.author | Gotuzzo, E. | - |
dc.date.accessioned | 2012-05-22T11:58:44Z | - |
dc.date.available | 2012-05-22T11:58:44Z | - |
dc.date.issued | 2007 | - |
dc.identifier.citation | EPIDEMIOLOGY AND INFECTION, 136 (8), p. 1076-1083 | - |
dc.identifier.issn | 0950-2688 | - |
dc.identifier.uri | http://hdl.handle.net/1942/13669 | - |
dc.description.abstract | SUMMARY:The purpose of this study was to assess the association between human T-lymphotropic virus 1 (HTLV-1) and a lifetime history of active tuberculosis (TB) among relatives of HTLV-1-infected patients. We reviewed clinical charts of all relatives of HTLV-1-infected index cases who attended our institute in Lima from 1990-2004. The data of 1233 relatives was analysed; 394 (32.0%) were HTLV-1 positive. Eighty-one subjects (6.6%) had a history of active TB, including 45/394 (11.4%) HTLV-1-positive and 36/839 (4.3%) HTLV-1-negative relatives (P<0.001). On multivariate analysis, three factors were associated with TB history: HTLV-1 infection (adjusted OR 2.5, 95% CI 1.6-3.9), age (adjusted OR 1.3, 95% CI 1.1-1.5 per 10-year age increase) and relation to the index case (adjusted OR 2.6, 95% CI 1.3-5.1, for siblings vs. spouses of index cases). In conclusion, HTLV-1 infection may increase the susceptibility to active TB. In populations where both infections are frequent, such an association could affect the dynamics of TB. | - |
dc.language.iso | en | - |
dc.title | HTLV-1 infection is associated with a history of active tuberculosis among family members of HTLV-1-infected patients in Peru | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 1083 | - |
dc.identifier.issue | 8 | - |
dc.identifier.spage | 1076 | - |
dc.identifier.volume | 136 | - |
local.format.pages | 1-8 | - |
local.bibliographicCitation.jcat | A1 | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.bibliographicCitation.oldjcat | A2 | - |
dc.identifier.doi | 10.1017/S0950268807009521 | - |
dc.identifier.isi | 000259748200008 | - |
item.fulltext | No Fulltext | - |
item.contributor | Verdonck, K. | - |
item.contributor | González, E. | - |
item.contributor | SCHROOTEN, Ward | - |
item.contributor | Vanham, G. | - |
item.contributor | Gotuzzo, E. | - |
item.fullcitation | Verdonck, K.; González, E.; SCHROOTEN, Ward; Vanham, G. & Gotuzzo, E. (2007) HTLV-1 infection is associated with a history of active tuberculosis among family members of HTLV-1-infected patients in Peru. In: EPIDEMIOLOGY AND INFECTION, 136 (8), p. 1076-1083. | - |
item.accessRights | Closed Access | - |
Appears in Collections: | Research publications |
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