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Title: Cognitive processes and attitudes in bipolar disorder: A study into personality, dysfunctional attitudes and attention bias in patients with bipolar disorder and their relatives
Authors: Jabben, Nienke
Arts, Baer
JONGEN, Ellen 
Smulders, Fren T. Y.
van Os, Jim
Krabbendam, Lydia
Issue Date: 2012
Source: JOURNAL OF AFFECTIVE DISORDERS, 143 (1-3), p. 265-268
Abstract: Background: Research in cognitive processes and attitudes in bipolar disorder is scarce and has provided mixed findings, possibly due to differences in current mood state. It is unclear whether alterations in cognitive processes and attitudes are only related to the depressive mood states of bipolar patients or also represent a vulnerability marker for the development of future (depressive) episodes. This was investigated in the current study. Methods: Both implicit (attentional bias for emotional words) and explicit (dysfunctional attitudes and personality characteristics) measures of cognitive processes and attitudes were assessed in 77 bipolar patients with varying levels of depressive symptoms (depressed = 17, euthymic n=60), their healthy first-degree relatives (n=39) and a healthy control group (n=61). Analyses of variance were used to investigate differences between groups. Results: Mildly depressed patients with bipolar disorder demonstrated an attentional bias away from positive emotional words and showed increased dysfunctional attitudes and higher levels of neuroticism. Euthymic patients were largely comparable to healthy controls and only differed from controls in higher levels of neuroticism. Relatives were similar to controls on all measures, although they significantly differed from bipolar patients in displaying less neuroticism and more extraversion. Limitations: No firm conclusions regarding causality can be drawn from the associations that were found between cognitive processes and attitudes and the evolution of mood symptoms in bipolar disorder. Conclusion: Alterations in cognitive processes and attitudes in bipolar patients appear to be mostly related to the expression of mood symptomatology rather than to the vulnerability for bipolar disorder. (C) 2012 Elsevier B.V. All rights reserved.
Notes: [Jabben, Nienke] Vrije Univ Amsterdam Med Ctr, EMGO Inst Hlth & Care Res, Dept Psychiat, NL-1081 HL Amsterdam, Netherlands. [Arts, Baer; van Os, Jim] Maastricht Univ, Med Ctr, Sch Mental Hlth & Neurosci, Dept Psychiat & Psychol, Maastricht, Netherlands. [Jongen, Ellen M. M.] Hasselt Univ, Transportat Res Inst Belgium, Diepenbeek, Belgium. [Smulders, Fren T. Y.] Maastricht Univ, Fac Psychol & Neurosci, Dept Cognit Neurosci, Maastricht, Netherlands. [van Os, Jim] Kings Coll London, Dept Psychosis Studies, Inst Psychiat, Kings Hlth Partners, London WC2R 2LS, England. [Krabbendam, Lydia] Vrije Univ Amsterdam, Fac Psychol & Educ, Dept Educ Neurosci, NL-1081 HL Amsterdam, Netherlands. [Krabbendam, Lydia] Vrije Univ Amsterdam, LEARNI Inst, NL-1081 HL Amsterdam, Netherlands.
Keywords: Clinical Neurology; Psychiatry; cognitive bias; psychological processing; bipolar disorder; vulnerability marker;Cognitive bias; Psychological processing; Bipolar disorder; Vulnerability marker
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ISSN: 0165-0327
e-ISSN: 1573-2517
DOI: 10.1016/j.jad.2012.04.022
ISI #: 000311213800040
Category: A1
Type: Journal Contribution
Validations: ecoom 2013
Appears in Collections:Research publications

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