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http://hdl.handle.net/1942/14729
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DC Field | Value | Language |
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dc.contributor.author | LIN, Dan | - |
dc.contributor.author | Djira, Gemechis D. | - |
dc.contributor.author | SHKEDY, Ziv | - |
dc.contributor.author | BURZYKOWSKI, Tomasz | - |
dc.contributor.author | Hothorn, Ludwig A. | - |
dc.date.accessioned | 2013-03-19T15:29:32Z | - |
dc.date.available | 2013-03-19T15:29:32Z | - |
dc.date.issued | 2012 | - |
dc.identifier.citation | Lin, D.; Shkedy, Z.; Yekutieli, D.; Amaratunga, D.; Bijnens, L. (Ed.). Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R: Order-Restricted Analysis of Microarray Data, p. 249-258 | - |
dc.identifier.isbn | 9783642240065 | - |
dc.identifier.issn | 2197-5736 | - |
dc.identifier.uri | http://hdl.handle.net/1942/14729 | - |
dc.description.abstract | In chap.16, we wish to search for genes for which the mean gene-expression increases by 100 ×δ% from the control for at least one (perhaps the highest) dose, where δ is a relative biological ratio of interest. Genes can be tested for a pre-specified δ and can be ranked based on the significance of the ratio test. Genes found significant with a large δ are of higher interest to the biologists. We discuss the ratio test statistic and the link between Williams- and Marcus-type multiple contrasts tests (MCTs) and the corresponding ratio testing procedures. | - |
dc.language.iso | en | - |
dc.publisher | Springer | - |
dc.relation.ispartofseries | Use R! | - |
dc.title | Simultaneous Inferences for Ratio Parameters Using Multiple Contrasts Test | - |
dc.type | Book Section | - |
local.bibliographicCitation.authors | Lin, D. | - |
local.bibliographicCitation.authors | Shkedy, Z. | - |
local.bibliographicCitation.authors | Yekutieli, D. | - |
local.bibliographicCitation.authors | Amaratunga, D. | - |
local.bibliographicCitation.authors | Bijnens, L. | - |
dc.identifier.epage | 258 | - |
dc.identifier.spage | 249 | - |
local.bibliographicCitation.jcat | B2 | - |
local.publisher.place | Heidelberg | - |
local.type.refereed | Refereed | - |
local.type.specified | Book Section | - |
dc.identifier.doi | 10.1007/978-3-642-24007-2_16 | - |
dc.identifier.url | http://www.ibiostat.be/software/IsoGeneGUI/Book.html | - |
local.bibliographicCitation.btitle | Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R: Order-Restricted Analysis of Microarray Data | - |
item.accessRights | Restricted Access | - |
item.contributor | LIN, Dan | - |
item.contributor | Djira, Gemechis D. | - |
item.contributor | SHKEDY, Ziv | - |
item.contributor | BURZYKOWSKI, Tomasz | - |
item.contributor | Hothorn, Ludwig A. | - |
item.fullcitation | LIN, Dan; Djira, Gemechis D.; SHKEDY, Ziv; BURZYKOWSKI, Tomasz & Hothorn, Ludwig A. (2012) Simultaneous Inferences for Ratio Parameters Using Multiple Contrasts Test. In: Lin, D.; Shkedy, Z.; Yekutieli, D.; Amaratunga, D.; Bijnens, L. (Ed.). Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R: Order-Restricted Analysis of Microarray Data, p. 249-258. | - |
item.fulltext | With Fulltext | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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Simultaneous.pdf Restricted Access | Peer-reviewed author version | 292.74 kB | Adobe PDF | View/Open Request a copy |
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