Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/14992
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | GIELEN, Heidi | - |
dc.contributor.author | REMANS, Tony | - |
dc.contributor.author | VANGRONSVELD, Jaco | - |
dc.contributor.author | CUYPERS, Ann | - |
dc.date.accessioned | 2013-04-08T12:51:06Z | - |
dc.date.available | 2013-04-08T12:51:06Z | - |
dc.date.issued | 2012 | - |
dc.identifier.citation | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 13 (12), p. 15826-15847 | - |
dc.identifier.issn | 1422-0067 | - |
dc.identifier.uri | http://hdl.handle.net/1942/14992 | - |
dc.description.abstract | In plants, microRNAs (miRNAs) control various biological processes by negatively regulating the expression of complementary target genes, either (1) post-transcriptionally by cleavage or translational inhibition of target mRNA, or (2) transcriptionally by methylation of target DNA. Besides their role in developmental processes, miRNAs are main players in stress responses, including metal stress responses. Exposure of plants to excess metal concentrations disturbs the cellular redox balance and enhances ROS accumulation, eventually leading to oxidative damage or signaling. Plants modify their gene expression by the activity of miRNAs in response to metal toxicity to regulate (1) complexation of excess metals, (2) defense against oxidative stress and (3) signal transduction for controlling various biological responses. This review focuses on the biogenesis, working mechanisms and functioning of miRNAs in plants. In a final part, our current knowledge on the regulatory roles of miRNAs in plant metal stress responses is highlighted, and whether stress-regulated miRNAs have specific roles or are secondary consequences is discussed. | - |
dc.language.iso | en | - |
dc.publisher | MDPI AG | - |
dc.subject.other | Chemistry, Multidisciplinary | - |
dc.subject.other | metals; oxidative stress; microRNA (miRNA); target gene | - |
dc.title | MicroRNAs in Metal Stress: Specific Roles or Secondary Responses? | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 15847 | - |
dc.identifier.issue | 12 | - |
dc.identifier.spage | 15826 | - |
dc.identifier.volume | 13 | - |
local.format.pages | 22 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | [Gielen, Heidi; Remans, Tony; Vangronsveld, Jaco; Cuypers, Ann] Hasselt Univ, Ctr Environm Sci, B-3590 Diepenbeek, Belgium. | - |
local.publisher.place | BASEL | - |
local.type.refereed | Refereed | - |
local.type.specified | Review | - |
dc.identifier.doi | 10.3390/ijms131215826 | - |
dc.identifier.isi | 000312608100020 | - |
item.contributor | GIELEN, Heidi | - |
item.contributor | REMANS, Tony | - |
item.contributor | VANGRONSVELD, Jaco | - |
item.contributor | CUYPERS, Ann | - |
item.fulltext | No Fulltext | - |
item.validation | ecoom 2014 | - |
item.fullcitation | GIELEN, Heidi; REMANS, Tony; VANGRONSVELD, Jaco & CUYPERS, Ann (2012) MicroRNAs in Metal Stress: Specific Roles or Secondary Responses?. In: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 13 (12), p. 15826-15847. | - |
item.accessRights | Closed Access | - |
crisitem.journal.issn | 1661-6596 | - |
crisitem.journal.eissn | 1422-0067 | - |
Appears in Collections: | Research publications |
SCOPUSTM
Citations
56
checked on Sep 3, 2020
WEB OF SCIENCETM
Citations
65
checked on May 1, 2024
Page view(s)
76
checked on Apr 17, 2023
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.