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http://hdl.handle.net/1942/15360
Title: | Long-term TENS treatment decreases cortical motor representation in multiple sclerosis | Authors: | CUYPERS, Koen LEENUS, Daphnie van den Berg, Femke Levin, Oron THIJS, Herbert Swinnen, Stephan MEESEN, Raf |
Issue Date: | 2013 | Source: | NEUROSCIENCE, 250, p. 1-7 | Abstract: | This study investigated the effect of a long-term transcutaneous electrical nerve stimulation (TENS) treatment on cortical motor representation in patients with multiple sclerosis (MS). In this double blind crossover design, patients received either TENS or sham stimulation for 3 weeks (1 hour per day) on the median nerve region of the most impaired hand, followed by the other stimulation condition after a washout period of 6 months. Cortical motor representation was mapped using transcranial magnetic stimulation (TMS) at baseline and after the 3-week stimulation protocol. Our results revealed that three weeks of daily stimulation with TENS significantly decreased the cortical motor representation of the stimulated muscle in MS patients. Although the mechanisms underlying this decrease remain unclear, our findings indicate that TENS has the ability to induce long-term reorganization in the motor cortex of MS patients. | Notes: | Meesen, RLJ (reprint author), REVAL Res Inst, Agoralaan,Bldg A, B-3590 Diepenbeek, Belgium. raf.meesen@uhasselt.be | Document URI: | http://hdl.handle.net/1942/15360 | ISSN: | 0306-4522 | e-ISSN: | 1873-7544 | DOI: | 10.1016/j.neuroscience.2013.06.046 | ISI #: | 000324847400001 | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2014 |
Appears in Collections: | Research publications |
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