Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/15360
Title: Long-term TENS treatment decreases cortical motor representation in multiple sclerosis
Authors: CUYPERS, Koen 
LEENUS, Daphnie 
van den Berg, Femke
Levin, Oron
THIJS, Herbert 
Swinnen, Stephan
MEESEN, Raf 
Issue Date: 2013
Source: NEUROSCIENCE, 250, p. 1-7
Abstract: This study investigated the effect of a long-term transcutaneous electrical nerve stimulation (TENS) treatment on cortical motor representation in patients with multiple sclerosis (MS). In this double blind crossover design, patients received either TENS or sham stimulation for 3 weeks (1 hour per day) on the median nerve region of the most impaired hand, followed by the other stimulation condition after a washout period of 6 months. Cortical motor representation was mapped using transcranial magnetic stimulation (TMS) at baseline and after the 3-week stimulation protocol. Our results revealed that three weeks of daily stimulation with TENS significantly decreased the cortical motor representation of the stimulated muscle in MS patients. Although the mechanisms underlying this decrease remain unclear, our findings indicate that TENS has the ability to induce long-term reorganization in the motor cortex of MS patients.
Notes: Meesen, RLJ (reprint author), REVAL Res Inst, Agoralaan,Bldg A, B-3590 Diepenbeek, Belgium. raf.meesen@uhasselt.be
Document URI: http://hdl.handle.net/1942/15360
ISSN: 0306-4522
e-ISSN: 1873-7544
DOI: 10.1016/j.neuroscience.2013.06.046
ISI #: 000324847400001
Category: A1
Type: Journal Contribution
Validations: ecoom 2014
Appears in Collections:Research publications

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