Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/15412
Title: Non-invasive cardiovascular profiling using combined electrocardiogram-Doppler ultrasonography and impedance cardiography: An experimental approach
Authors: TOMSIN, Kathleen 
Vriens, Annette
Mesens, Tinne
GYSELAERS, Wilfried 
Issue Date: 2013
Publisher: WILEY-BLACKWELL
Source: CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 40 (7), p. 438-442
Abstract: In the present study, the feasibility of cardiovascular profiling using both combined electrocardiogram (ECG)-Doppler ultrasonography and impedance cardiography (ICG) was evaluated. Fourteen non-pregnant healthy women received 500mL saline solution (NaCl 0.9% at 999mL/h) intravenously by steady state infusion. Before and after this acute volume loading, we measured orthostatic-challenged cardiac and arterial characteristics using ICG and assessed venous characteristics by combined ECG-Doppler before and during the Valsalva manoeuvre. Changes are expressed as the mean +/- SEM and were evaluated by the one-sample Wilcoxon signed-rank test. After volume loading, the observed fall in stroke volume after postural change from supine to standing decreased (-14 +/- 3 vs -23 +/- 2%; P=0.011). Hepatic A wave velocity increased 63 +/- 28% after volume loading (P=0.007) and decreased during the Valsalva manoeuvre (-205 +/- 21%; P=0.001). Volume loading raised the thoracic fluid content index in both the supine and standing positions (7 +/- 2% and 10 +/- 1%, respectively; P0.014). Combined ECG-Doppler ultrasonography and ICG enables the non-invasive identification of concomitant haemodynamic changes at the level of the heart, the arterial bed and the venous compartment. Our data support the view that non-invasive cardiovascular profiling is feasible, which seems particularly useful for the evaluation of patients who are not critically ill, such as pregnant women.
Notes: Tomsin, K (reprint author), Ziekenhuis Oost Limburg, Dept Obstet & Gynaecol, B-3600 Genk, Belgium. Hasselt Univ, Fac Med & Life Sci, Diepenbeek, Belgium. kathleen.tomsin@ZOL.be
Keywords: cardiovascular physiology; Doppler ultrasound; feasibility studies; impedance cardiography;Pharmacology & Pharmacy; Physiology
Document URI: http://hdl.handle.net/1942/15412
ISSN: 1440-1681
DOI: 10.1111/1440-1681.12105
ISI #: 000320781400007
Category: A1
Type: Journal Contribution
Validations: ecoom 2014
Appears in Collections:Research publications

Files in This Item:
File Description SizeFormat 
tomsin 1.pdf
  Restricted Access
published version219.96 kBAdobe PDFView/Open    Request a copy
Show full item record

SCOPUSTM   
Citations

14
checked on Sep 3, 2020

WEB OF SCIENCETM
Citations

13
checked on May 13, 2022

Page view(s)

58
checked on May 15, 2022

Download(s)

56
checked on May 15, 2022

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.