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http://hdl.handle.net/1942/15502
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DC Field | Value | Language |
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dc.contributor.author | van der Donk, Christina | - |
dc.contributor.author | van de Bovenkamp, Jeroen | - |
dc.contributor.author | Bamelis, Hans | - |
dc.contributor.author | Driessen, Christel | - |
dc.contributor.author | Feldhoff, Karl-Heinz | - |
dc.contributor.author | Kalka-Moll, Wiltrud | - |
dc.contributor.author | MAGERMAN, Koen | - |
dc.contributor.author | Stobberingh, Ellen | - |
dc.date.accessioned | 2013-09-20T10:50:39Z | - |
dc.date.available | 2013-09-20T10:50:39Z | - |
dc.date.issued | 2013 | - |
dc.identifier.citation | FUTURE MICROBIOLOGY, 8 (8), p. 1027-1037 | - |
dc.identifier.issn | 1746-0913 | - |
dc.identifier.uri | http://hdl.handle.net/1942/15502 | - |
dc.description.abstract | Aim: To investigate the prevalence and genetic background of Escherichia coli collected from different patient populations in the Euroregion Meuse-Rhine. Materials & methods: Susceptibility testing was performed on 1651 E. coli isolates with broth microdilution. Their genetic background was determined using pulsed-field gel electrophoresis and multilocus sequence typing. Results: The prevalence of resistance varied significantly between the populations. Approximately 10% of the E. coli isolates were multidrug-resistant and/or a β-lactamase producer. The most prevalent extended-spectrum β-lactamase type was CTX-M-15 and ST131 was the most prevalent multilocus sequence typing type. Results from pulsed-field gel electrophoresis of the ST131 isolates indicate the spread of these isolates in the Euroregion. Conclusion: E. coli ST131 was the most prevalent sequence type in our Euroregional study. It is essential to control the spread of these resistant strains (e.g., with infection-control policies, antibiotic stewardship programs and antibiotic resistance surveillance). In this way we could observe shifts in the prevalence of resistance of the E. coli population and act accordingly. | - |
dc.description.sponsorship | This project was financially supported by Provincie Limburg, The Netherlands; Ministerium fur Wirtschaft, Energie, Bauen, Wohnen und Verkehr des Landes Nordrhein-Westfalen, Germany; Ministerium der Deutschsprachige Gemeinschaft Belgiens, Belgium; Provincie Limburg, Belgium; Wallonie, Belgium; Rheinland-Westfalen, Germany; Interreg; and the Euregio Maas-Rijn with support of the European fund for regional development. The funding institutions were not involved in any part of this study. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. | - |
dc.language.iso | en | - |
dc.subject.other | antibiotic resistance; cross-border; Escherichia coli; extended-spectrum beta-lactamases; multilocus sequence typing; ST131 | - |
dc.title | Prevalence and spread of multidrug-resistant Escherichia coli including ST131 in different patient populations in the Euroregion Meuse-Rhine | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 1037 | - |
dc.identifier.issue | 8 | - |
dc.identifier.spage | 1027 | - |
dc.identifier.volume | 8 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Stobberingh, E (reprint author), Maastricht Univ, Dept Med Microbiol, Med Ctr, P Debyelaan 25, NL-6229 HX Maastricht, Netherlands. e.stobberingh@gmail.com | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.2217/FMB.13.61 | - |
dc.identifier.isi | 000323229800014 | - |
item.fulltext | No Fulltext | - |
item.contributor | van der Donk, Christina | - |
item.contributor | van de Bovenkamp, Jeroen | - |
item.contributor | Bamelis, Hans | - |
item.contributor | Driessen, Christel | - |
item.contributor | Feldhoff, Karl-Heinz | - |
item.contributor | Kalka-Moll, Wiltrud | - |
item.contributor | MAGERMAN, Koen | - |
item.contributor | Stobberingh, Ellen | - |
item.accessRights | Closed Access | - |
item.fullcitation | van der Donk, Christina; van de Bovenkamp, Jeroen; Bamelis, Hans; Driessen, Christel; Feldhoff, Karl-Heinz; Kalka-Moll, Wiltrud; MAGERMAN, Koen & Stobberingh, Ellen (2013) Prevalence and spread of multidrug-resistant Escherichia coli including ST131 in different patient populations in the Euroregion Meuse-Rhine. In: FUTURE MICROBIOLOGY, 8 (8), p. 1027-1037. | - |
crisitem.journal.issn | 1746-0913 | - |
crisitem.journal.eissn | 1746-0921 | - |
Appears in Collections: | Research publications |
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