Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/15713
Full metadata record
DC FieldValueLanguage
dc.contributor.advisorBURZYKOWSKI, Tomasz-
dc.contributor.advisorLITIERE, Saskia-
dc.contributor.authorGachau, Susan-
dc.date.accessioned2013-10-01T14:48:08Z-
dc.date.available2013-10-01T14:48:08Z-
dc.date.issued2013-
dc.identifier.urihttp://hdl.handle.net/1942/15713-
dc.description.abstractABSTRACT Background: Soft-tissue sarcomas (STS) are a rare and heterogeneous group of tumors of mesenchymal origin and can start in any part of the body mainly in support and connective tissues. When performing large multicenter clinical trials, a lot of attention is paid to the standardization of the treatment procedures across the participating sites. This is done to ensure that the difference in effect observed between treatment arms, can be completely attributed to the difference in treatments. This is because heterogeneity between the participating centers may add noise to the estimation of the treatment effect. Objective: The overall objective was to investigate the impact of institution variability on patient outcome in a soft tissue sarcoma clinical trial. Specifically, to compare parameter estimates from different statistical analysis methods as well as investigate the impact of frailty misspecification on parameters of interest. Methods: In statistical analysis, semi-
dc.format.mimetypeApplication/pdf-
dc.languageen-
dc.language.isoen-
dc.publishertUL-
dc.titleThe impact of institution variability on patients outcome in a soft tissue sarcoma clinical trial-
dc.typeTheses and Dissertations-
local.format.pages0-
local.bibliographicCitation.jcatT2-
dc.description.notesMaster of Statistics-Biostatistics-
local.type.specifiedMaster thesis-
item.accessRightsOpen Access-
item.contributorGachau, Susan-
item.fulltextWith Fulltext-
item.fullcitationGachau, Susan (2013) The impact of institution variability on patients outcome in a soft tissue sarcoma clinical trial.-
Appears in Collections:Master theses
Files in This Item:
File Description SizeFormat 
11317202012009.pdf858.26 kBAdobe PDFView/Open
Show simple item record

Page view(s)

30
checked on Oct 30, 2023

Download(s)

10
checked on Oct 30, 2023

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.