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http://hdl.handle.net/1942/15762
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DC Field | Value | Language |
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dc.contributor.advisor | BOYEN, Hans-Gerd | - |
dc.contributor.advisor | SCHEER, Elke | - |
dc.contributor.author | ARTOIS, Joris | - |
dc.date.accessioned | 2013-10-01T14:48:19Z | - |
dc.date.available | 2013-10-01T14:48:19Z | - |
dc.date.issued | 2013 | - |
dc.identifier.uri | http://hdl.handle.net/1942/15762 | - |
dc.description.abstract | We studied short single-DNA molecules, using the mechanically controllable break junction technique (MCBJ). We measured two different sequences. The first resulted in a single-DNA conductance of 1.6 ' 2.0 10-4 G0 in high-vacuum (with G0 the quantum of conductance). The other sequence with an induced bulge, an unpaired nucleotide on one strand, was measured in aqueous as well as in high-vacuum conditions. To broaden our measurement range to ultralow conductance, a method was developed to reduce the ionic conduction of the buffer. The measurements resulted in a conductance value for a single-DNA molecule of 10-5 G0. We can conclude that we were able to measure the electric transport through single-DNA molecules using a MCBJ setup in different conditions, for different sequences. It is clear that environmental factors play a huge role in determining the conductance, and that the understanding of a complex system like DNA is challenging. | - |
dc.format.mimetype | Application/pdf | - |
dc.language | nl | - |
dc.language.iso | en | - |
dc.publisher | tUL | - |
dc.title | Impact of the sequence of base pairs onto the electrical transport through single DNA molecules | - |
dc.type | Theses and Dissertations | - |
local.bibliographicCitation.jcat | T2 | - |
dc.description.notes | master in de biomedische wetenschappen-bio-elektronica en nanotechnologie | - |
local.type.specified | Master thesis | - |
item.fullcitation | ARTOIS, Joris (2013) Impact of the sequence of base pairs onto the electrical transport through single DNA molecules. | - |
item.fulltext | With Fulltext | - |
item.contributor | ARTOIS, Joris | - |
item.accessRights | Open Access | - |
Appears in Collections: | Master theses |
Files in This Item:
File | Description | Size | Format | |
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11316762012254.pdf | 14.06 MB | Adobe PDF | View/Open |
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