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http://hdl.handle.net/1942/15951
Title: | Which Immune Cells Matter? The Immunopathogenesis of Multiple Sclerosis | Authors: | BROUX, Bieke STINISSEN, Piet HELLINGS, Niels |
Issue Date: | 2013 | Source: | CRITICAL REVIEWS IN IMMUNOLOGY, 33 (4), p. 283-306 | Abstract: | Multiple sclerosis (MS) is a complex disease of the central nervous system (CNS), which is believed to be immune-mediated. While CD4(+) T cells have been the main suspects for years, there is ample evidence that other immune cells (including those of the innate immune system) play a contributing or regulating role in this disease. After a general introduction, this review focuses on different immune cell subsets implicated in MS pathogenesis and on current and future possibilities to target them for therapeutic use. | Document URI: | http://hdl.handle.net/1942/15951 | ISSN: | 1040-8401 | e-ISSN: | 2162-6472 | ISI #: | 000325189900001 | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2014 |
Appears in Collections: | Research publications |
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