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http://hdl.handle.net/1942/16460
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DC Field | Value | Language |
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dc.contributor.author | Manders, Ralph | - |
dc.contributor.author | HANSEN, Dominique | - |
dc.contributor.author | Zorenc, Antoine | - |
dc.contributor.author | DENDALE, Paul | - |
dc.contributor.author | Kloek, Joris | - |
dc.contributor.author | SARIS, W.H.M. | - |
dc.contributor.author | van Loon, Luc | - |
dc.date.accessioned | 2014-03-20T15:56:39Z | - |
dc.date.available | 2014-03-20T15:56:39Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | JOURNAL OF MEDICINAL FOOD 17(7), p. 758-763. | - |
dc.identifier.issn | 1096-620X | - |
dc.identifier.uri | http://hdl.handle.net/1942/16460 | - |
dc.description.abstract | The capacity of nutritional protein to induce endogenous insulin secretion has been well established. However, it is not known whether such a response is applicable in a diverse population of type 2 diabetes patients. The aim of the present study was to assess the impact of co-ingesting either intact or hydrolyzed protein with carbohydrate on postprandial plasma insulin and glucose responses in type 2 diabetes patients. Sixty longstanding, male, type 2 diabetes patients participated in a study in which we determined postprandial plasma insulin and glucose responses after ingesting a single bolus of carbohydrate (0.7 g/kg: CHO) with or without an intact protein (0.3 g/kg: PRO) or its hydrolysate (0.3 g/kg: PROh). Results showed that protein co-ingestion strongly increased postprandial insulin release, with the insulin response +99–41 and +110–10% greater in the CHO+PRO and CHO+PROh experiments when compared with the CHO experiment. The insulinotropic properties of protein co-ingestion were evident in nearly all patients, with 58 out of 60 patients responding >10% when compared with the insulin response following carbohydrate ingestion only (CHO). The concomitant plasma glucose responses were 22–32 and 23–36% lower in the CHO+PRO and CHO+PROh experiments, respectively. We conclude that protein co-ingestion represents an effective dietary strategy to strongly augment postprandial insulin release and attenuate the postprandial rise in glucose concentration in type 2 diabetes patients. | - |
dc.language.iso | en | - |
dc.rights | © Mary Ann Liebert, Inc., and Korean Society of Food Science and Nutrition. | - |
dc.subject.other | glucose; insulin; milk protein; protein hydrolysates | - |
dc.title | Protein Co-Ingestion Strongly Increases Postprandial Insulin Secretion in Type 2 Diabetes Patients | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 763 | - |
dc.identifier.issue | 7 | - |
dc.identifier.spage | 758 | - |
dc.identifier.volume | 17 | - |
local.bibliographicCitation.jcat | A1 | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1089/jmf.2012.0294 | - |
item.fullcitation | Manders, Ralph; HANSEN, Dominique; Zorenc, Antoine; DENDALE, Paul; Kloek, Joris; SARIS, W.H.M. & van Loon, Luc (2014) Protein Co-Ingestion Strongly Increases Postprandial Insulin Secretion in Type 2 Diabetes Patients. In: JOURNAL OF MEDICINAL FOOD 17(7), p. 758-763.. | - |
item.fulltext | With Fulltext | - |
item.accessRights | Restricted Access | - |
item.contributor | Manders, Ralph | - |
item.contributor | HANSEN, Dominique | - |
item.contributor | Zorenc, Antoine | - |
item.contributor | DENDALE, Paul | - |
item.contributor | Kloek, Joris | - |
item.contributor | SARIS, W.H.M. | - |
item.contributor | van Loon, Luc | - |
crisitem.journal.issn | 1096-620X | - |
crisitem.journal.eissn | 1557-7600 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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manders et al. j med food.pdf Restricted Access | 175.28 kB | Adobe PDF | View/Open Request a copy |
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