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http://hdl.handle.net/1942/16684
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DC Field | Value | Language |
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dc.contributor.author | Subramanian, Palaniappan | - |
dc.contributor.author | Motorina, Anastasiia | - |
dc.contributor.author | YEAP, Weng Siang | - |
dc.contributor.author | HAENEN, Ken | - |
dc.contributor.author | Coffinier, Yannick | - |
dc.contributor.author | Zaitsev, Vladimir | - |
dc.contributor.author | Niedziolka-Jonsson, Joanna | - |
dc.contributor.author | Boukherroub, Rabah | - |
dc.contributor.author | Szunerits, Sabine | - |
dc.date.accessioned | 2014-04-25T10:06:23Z | - |
dc.date.available | 2014-04-25T10:06:23Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | ANALYST, 139 (7), p. 1726-1731 | - |
dc.identifier.issn | 0003-2654 | - |
dc.identifier.uri | http://hdl.handle.net/1942/16684 | - |
dc.description.abstract | Nanostructured boron-doped diamond has been investigated as a sensitive impedimetric electrode for the detection of immunoglobulin G (IgG). The immunosensor was constructed in a three-step process: (i) reactive ion etching of flat boron-doped diamond (BDD) interfaces to synthesize BDD nanowires (BDD NWs), (ii) electrochemical deposition of nickel nanoparticles (Ni NPs) on the BDD NWs, and (iii) immobilization of biotin-tagged anti-IgG onto the Ni NPs. Electrochemical impedance spectroscopy (EIS) was used to follow the binding of IgG at different concentrations without the use of any additional label. A detection limit of 0.3 ng mL−1 (2 nM) with a dynamic range up to 300 ng mL−1 (2 μM) was obtained with the interface. Moreover, the study demonstrated that this immunosensor exhibits good stability over time and allows regeneration by incubation in ethylenediaminetetraacetic acid (EDTA) aqueous solution. | - |
dc.description.sponsorship | R.B, Y.C. and S. S. gratefully acknowledge the financial support from the Centre National de Recherche Scientifique (CNRS), the Universite Lille 1 and the Nord Pas de Calais region. Support from the European Union through a FP7-PEOPLE-IRSES (PHO-TORELEASE) and FP7-PEOPLE-ITN (MATCON) are acknowledged. Many thanks to Mr Sobczak in obtaining the XPS data. | - |
dc.language.iso | en | - |
dc.rights | This journal is © The Royal Society of Chemistry 2014 | - |
dc.title | An impedimetric immunosensor based on diamond nanowires decorated with nickel nanoparticles | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 1731 | - |
dc.identifier.issue | 7 | - |
dc.identifier.spage | 1726 | - |
dc.identifier.volume | 139 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Szunerits, S (reprint author), Univ Lille 1, CNRS USR 3078, IRI, Parc Haute Borne,50 Ave Halley,BP 70478, F-59658 Villeneuve Dascq, France. | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1039/c3an02045b | - |
dc.identifier.isi | 000332422400021 | - |
item.fullcitation | Subramanian, Palaniappan; Motorina, Anastasiia; YEAP, Weng Siang; HAENEN, Ken; Coffinier, Yannick; Zaitsev, Vladimir; Niedziolka-Jonsson, Joanna; Boukherroub, Rabah & Szunerits, Sabine (2014) An impedimetric immunosensor based on diamond nanowires decorated with nickel nanoparticles. In: ANALYST, 139 (7), p. 1726-1731. | - |
item.fulltext | With Fulltext | - |
item.validation | ecoom 2015 | - |
item.contributor | Subramanian, Palaniappan | - |
item.contributor | Motorina, Anastasiia | - |
item.contributor | YEAP, Weng Siang | - |
item.contributor | HAENEN, Ken | - |
item.contributor | Coffinier, Yannick | - |
item.contributor | Zaitsev, Vladimir | - |
item.contributor | Niedziolka-Jonsson, Joanna | - |
item.contributor | Boukherroub, Rabah | - |
item.contributor | Szunerits, Sabine | - |
item.accessRights | Restricted Access | - |
crisitem.journal.issn | 0003-2654 | - |
crisitem.journal.eissn | 1364-5528 | - |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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subramanian 1.pdf Restricted Access | Published version | 461.7 kB | Adobe PDF | View/Open Request a copy |
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