Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/16977
Title: Real-time detection of CO by eukaryotic cells
Authors: BOHRN, Ulrich 
Stuetz, E.
Fleischer, M.
Schoening, M.
WAGNER, Patrick 
Issue Date: 2010
Publisher: ELSEVIER SCIENCE BV
Source: Jakoby, B Vellekoop, MJ (Ed.). EUROSENSORS XXIV CONFERENCE, p. 17-20
Series/Report: Procedia Engineering
Abstract: In this contribution, we focus on the detection of toxic gases with living eukaryotic cells. A cell-based gas sensor system, able to measure the effects of direct exposure of gases to cells in real-time, was set up. Impedance data as well as oxygen consumption of Chinese hamster lung fibroblast cells (V79) were analysed upon exposure to carbon monoxide (CO). The CO (diluted in wet synthetic air) affects the cell respiration as indicated by an attenuated respiration signal after the CO exposure as well as an instant increase of the capacitive part of the impedance signal during the gas exposure. (C) 2010 Published by Elsevier Ltd.
Notes: [Bohrn, U.; Stuetz, E.; Fleischer, M.] Siemens AG, Corp Res & Technol, D-81739 Munich, Germany.
Keywords: carbon monoxide; cell-based sensor; impedance; respiration; toxicity; V79;Chemistry, Analytical; Engineering, Electrical & Electronic; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary
Document URI: http://hdl.handle.net/1942/16977
DOI: 10.1016/j.proeng.2010.09.037
ISI #: 000287162400005
Category: C1
Type: Proceedings Paper
Appears in Collections:Research publications

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