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Title: Morphological substrates in Rheumatoid Arthritis pathogenesis
Authors: VAN ZWIETEN, Koos Jaap 
DE BAKKER, Bernadette
KOSTEN, Lauren
DE MUNTER, Stephanie
Issue Date: 2014
Publisher: VITO Vision On Technology, Universiteit Hasselt, BIOMED Biomedisch Onderzoeksinstituut
Source: Ameloot, Marcel; Bové, Hannelore; Penjweini, Rozhin; Deville, Sarah; Comhair, Joris; Slenders, Eli (Ed.). µFiBR 2014 - Abstract book, A series of tutorial lectures on Optical Imaging in Biomedical Nanotechnology, 3 October 2014, Diepenbeek, Belgium, p. 61-62
Series/Report: 3
Series/Report no.: 1
Abstract: In the PIP joint capsule of the finger, neurofilaments and lamellated corpuscules are observed, comparable with those present in human facet joints. Our study demonstrated these corpuscules in the PIP Proper Collateral Ligament for the first time. Supposedly acting as mechanoreceptors, they may also produce cytokines and substance P, a neuropeptide involved in pain. As the PIP joints of fingers in particular show symptoms of Rheumatoid Arthritis at very early stages, these organs may therefore play a role in the pathogenesis of Rheumatoid Arthritis.
Notes: Presentation A-20, 12.35 - 14.00 h
Keywords: joint morphogenesis; synovial folds; rheumatoid arthritis; neurofilaments
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Rights: University of Hasselt, Diepenbeek, Belgium
Category: C2
Type: Proceedings Paper
Appears in Collections:Research publications

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