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http://hdl.handle.net/1942/17879
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DC Field | Value | Language |
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dc.contributor.author | OBEN, Jolien | - |
dc.contributor.author | TOMSIN, Kathleen | - |
dc.contributor.author | Mesens, Tinne | - |
dc.contributor.author | STAELENS, Anneleen | - |
dc.contributor.author | MOLENBERGHS, Geert | - |
dc.contributor.author | GYSELAERS, Wilfried | - |
dc.date.accessioned | 2014-11-25T10:37:18Z | - |
dc.date.available | 2014-11-25T10:37:18Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, 27 (16), p. 1646-1651 | - |
dc.identifier.issn | 1476-7058 | - |
dc.identifier.uri | http://hdl.handle.net/1942/17879 | - |
dc.description.abstract | Objective: In this study, we determine whether maternal cardiovascular (CV) profiling can detect first trimester differences between women with uncomplicated pregnancies (UP) and those who will develop gestational hypertensive disorders (GHD) or normotensive fetal growth retardation (FGR). Methods: Cardiac, arterial, and venous function were evaluated in 242 pregnant women around 12 weeks of gestation, using impedance cardiography (ICG) and combined electrocardiogram Doppler ultrasonography. After postnatal determination of gestational outcome, first trimester measurements were compared between groups using Mann-Whitney U test for continuous data or Fisher's Exact test for categorical variables (SPSS 20.0). Results: Compared to UP, first trimester aortic flow velocity index [71 +/- 0.96 versus 61 +/- 4.91 1/1000/s (p = 0.016)], acceleration index [133 +/- 2.25 versus 106 +/- 11.26 1/100/s(2) (p = 0.023)] and Heather index [23.1 +/- 0.35 versus 19.2 +/- 1.70 Omega/s(2) (p = 0.019)] were lower in GHD pregnancies, and first trimester stroke volume [77 +/- 1.16 versus 67 +/- 3.97 ml (p = 0.033)] and cardiac output [7.3 +/- 0.10 versus 6.2 +/- 0.31 l/min (p = 0.025)] were lower in FGR pregnancies. Conclusions: Maternal CV function in the first trimester of pregnancy differs between UP and those destined to develop GHD or FGR. This can be assessed with non-invasive maternal CV profiling, opening perspectives for the application of this technique in early gestational screening for GHD and FGR. | - |
dc.description.sponsorship | The medical company Medis is acknowledged for its supply of ICG-electrodes for this study. | - |
dc.language.iso | en | - |
dc.publisher | INFORMA HEALTHCARE | - |
dc.rights | (C) 2014 Informa UK Ltd | - |
dc.subject.other | Cardiovascular profiling; fetal growth retardation; gestational hypertension; gestational hypertensive disorders; impedance cardiography; pre-eclampsia; screening; vascular Doppler | - |
dc.subject.other | cardiovascular profiling; fetal growth retardation; gestational hypertension; gestational hypertensive disorders; impedance cardiography; pre-eclampsia; screening; vascular Doppler | - |
dc.title | Maternal cardiovascular profiling in the first trimester of pregnancies complicated with gestation-induced hypertension or fetal growth retardation: a pilot study | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 1651 | - |
dc.identifier.issue | 16 | - |
dc.identifier.spage | 1646 | - |
dc.identifier.volume | 27 | - |
local.format.pages | 6 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | [Oben, Jolien; Tomsin, Kathleen; Mesens, Tinne; Staelens, Anneleen; Gyselaers, Wilfried] Ziekenhuis Oost Limburg, Dept Obstet & Gynaecol, B-3600 Genk, Belgium. [Oben, Jolien; Tomsin, Kathleen; Staelens, Anneleen] Hasselt Univ, Fac Med & Life Sci, Hasselt, Belgium. [Molenberghs, Geert] Hasselt Univ, I BioStat, Hasselt, Belgium. [Gyselaers, Wilfried] Hasselt Univ, Dept Physiol, Hasselt, Belgium. | - |
local.publisher.place | LONDON | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.3109/14767058.2013.871700 | - |
dc.identifier.isi | 000343031000007 | - |
dc.identifier.url | https://www.researchgate.net/publication/259152267_Maternal_cardiovascular_profiling_in_the_first_trimester_of_pregnancies_complicated_with_gestation-induced_hypertension_or_fetal_growth_retardation_A_pilot_study | - |
item.fulltext | With Fulltext | - |
item.accessRights | Restricted Access | - |
item.validation | ecoom 2015 | - |
item.contributor | OBEN, Jolien | - |
item.contributor | TOMSIN, Kathleen | - |
item.contributor | Mesens, Tinne | - |
item.contributor | STAELENS, Anneleen | - |
item.contributor | MOLENBERGHS, Geert | - |
item.contributor | GYSELAERS, Wilfried | - |
item.fullcitation | OBEN, Jolien; TOMSIN, Kathleen; Mesens, Tinne; STAELENS, Anneleen; MOLENBERGHS, Geert & GYSELAERS, Wilfried (2014) Maternal cardiovascular profiling in the first trimester of pregnancies complicated with gestation-induced hypertension or fetal growth retardation: a pilot study. In: JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, 27 (16), p. 1646-1651. | - |
crisitem.journal.issn | 1476-7058 | - |
crisitem.journal.eissn | 1476-4954 | - |
Appears in Collections: | Research publications |
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oben2014.pdf Restricted Access | Published version | 432.8 kB | Adobe PDF | View/Open Request a copy |
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