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http://hdl.handle.net/1942/18038
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DC Field | Value | Language |
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dc.contributor.author | Fonseca, Gabriel P. | - |
dc.contributor.author | RENIERS, Brigitte | - |
dc.contributor.author | Landry, Guillaume | - |
dc.contributor.author | White, Shane | - |
dc.contributor.author | Bellezzo, Murillo | - |
dc.contributor.author | Antunes, Paula C.G. | - |
dc.contributor.author | de Sales, Camila P. | - |
dc.contributor.author | Welteman, Eduardo | - |
dc.contributor.author | Yoriyaz, Helio | - |
dc.contributor.author | Verhaegen, Frank | - |
dc.date.accessioned | 2014-12-19T12:44:30Z | - |
dc.date.available | 2014-12-19T12:44:30Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | BRACHYTHERAPY, 13 (6), p. 632-639 | - |
dc.identifier.issn | 1538-4721 | - |
dc.identifier.uri | http://hdl.handle.net/1942/18038 | - |
dc.description.abstract | PURPOSE: Brachytherapy dose calculation is commonly performed using the Task Group-No 43 Report-Updated protocol (TG-43U1) formalism. Recently, a more accurate approach has been proposed that can handle tissue composition, tissue density, body shape, applicator geometry, and dose reporting either in media or water. Some model-based dose calculation algorithms are based on Monte Carlo (MC) simulations. This work presents a software platform capable of processing medical images and treatment plans, and preparing the required input data for MC simulations. METHODS AND MATERIALS: The A Medical Image-based Graphical platfOrm Brachytherapy module (AMIGOBrachy) is a user interface, coupled to the MCNP6 MC code, for absorbed dose calculations. The AMIGOBrachy was first validated in water for a high-dose-rate Ir-192 source. Next, dose distributions were validated in uniform phantoms consisting of different materials. Finally, dose distributions were obtained in patient geometries. Results were compared against a treatment planning system including a linear Boltzmann transport equation (LBTE) solver capable of handling nonwater heterogeneities. RESULTS: The TG-43U1 source parameters are in good agreement with literature with more than 90% of anisotropy values within 1%. No significant dependence on the tissue composition was observed comparing MC results against an LBTE solver. Clinical cases showed differences up to 25%, when comparing MC results against TG-43U1. About 92% of the voxels exhibited dose differences lower than 2% when comparing MC results against an LBTE solver. CONCLUSION: The AMIGOBrachy can improve the accuracy of the TG-43U1 dose calculation by using a more accurate MC dose calculation algorithm. The AMIGOBrachy can be incorporated in clinical practice via a user-friendly graphical interface. (C) 2014 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved. | - |
dc.description.sponsorship | Fundacao de Amparo a Pesquisa do Estado de Sao Paulo [2011/01913-4, 2011/23765-7, 2011/22778-8]; Canadian Cancer Society Research Institute [2011-700810]; Natural Sciences and Engineering Research Council of Canada; O'Brien Foundation; Marie Curie Reintegration Grant [PIRG05-GA-2009-247878] | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.rights | Copyright © 2014 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved. | - |
dc.subject.other | brachytherapy; Monte Carlo; model-based dose calculation algorithms; user interface | - |
dc.subject.other | Brachytherapy; Monte Carlo; Model-based dose calculation algorithms; User interface | - |
dc.title | A medical image-based graphical platform-Features, applications and relevance for brachytherapy | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 639 | - |
dc.identifier.issue | 6 | - |
dc.identifier.spage | 632 | - |
dc.identifier.volume | 13 | - |
local.format.pages | 8 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | [Fonseca, Gabriel P.; Bellezzo, Murillo; Antunes, Paula C. G.; Yoriyaz, Helio] Inst Pesquisas Energet & Nucl IPEN, CNEN SP, Ctr Engn Nucl, Sao Paulo, Brazil. [Fonseca, Gabriel P.; Reniers, Brigitte; Landry, Guillaume; White, Shane; Verhaegen, Frank] Maastricht Univ, Med Ctr, GROW Sch Oncol & Dev Biol, Dept Radiat Oncol MAASTRO, NL-6201 BN Maastricht, Netherlands. [Reniers, Brigitte] Hasselt Univ, Ctr Environm Sci, Res Grp NuTeC, Diepenbeek, Belgium. [Landry, Guillaume] Univ Munich, Dept Med Phys, Garching, Germany. [de Sales, Camila P.] Univ Sao Paulo, Inst Radiol, Hosp Clin, HC FMUSP, Sao Paulo, Brazil. [Welteman, Eduardo] Univ Sao Paulo, Fac Med, HC FMUSP, Sao Paulo, Brazil. [Verhaegen, Frank] McGill Univ, Dept Oncol, Med Phys Unit, Montreal, PQ, Canada. | - |
local.publisher.place | NEW YORK | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1016/j.brachy.2014.07.004 | - |
dc.identifier.isi | 000344137000016 | - |
item.fulltext | No Fulltext | - |
item.fullcitation | Fonseca, Gabriel P.; RENIERS, Brigitte; Landry, Guillaume; White, Shane; Bellezzo, Murillo; Antunes, Paula C.G.; de Sales, Camila P.; Welteman, Eduardo; Yoriyaz, Helio & Verhaegen, Frank (2014) A medical image-based graphical platform-Features, applications and relevance for brachytherapy. In: BRACHYTHERAPY, 13 (6), p. 632-639. | - |
item.contributor | Fonseca, Gabriel P. | - |
item.contributor | RENIERS, Brigitte | - |
item.contributor | Landry, Guillaume | - |
item.contributor | White, Shane | - |
item.contributor | Bellezzo, Murillo | - |
item.contributor | Antunes, Paula C.G. | - |
item.contributor | de Sales, Camila P. | - |
item.contributor | Welteman, Eduardo | - |
item.contributor | Yoriyaz, Helio | - |
item.contributor | Verhaegen, Frank | - |
item.accessRights | Closed Access | - |
item.validation | ecoom 2015 | - |
crisitem.journal.issn | 1538-4721 | - |
crisitem.journal.eissn | 1873-1449 | - |
Appears in Collections: | Research publications |
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