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Title: | Determinants of bisphenol A and phthalate metabolites in urine of Flemish adolescents | Authors: | Geens, Tinne BRUCKERS, Liesbeth Covaci, Adrian Schoeters, Greet Fierens, Tine Sioen, Isabelle Vanermen, Guido Baeyens, Willy Morrens, Bert Loots, Ilse Nelen, Vera de Bellevaux, Benoit Nemery Van Larebeke, Nik Den Hond, Elly |
Issue Date: | 2014 | Publisher: | ACADEMIC PRESS INC ELSEVIER SCIENCE | Source: | ENVIRONMENTAL RESEARCH, 134, p. 110-117 | Abstract: | As part of the second Flemish Environment and Health Study (FLEHS II), bisphenol-A (BPA) and different phthalate metabolites were analyzed, for the first time, in the urine of 210 adolescents in Flanders, Belgium. All chemicals had a detection frequency above 90%. For all compounds, except the sum of DEHP, highest levels were detected during spring. Average values for the Flemish adolescents were in an agreement with concentrations found in different international studies, all confirming the ubiquity of BPA and phthalate exposure. There was a significant correlation between BPA and the different phthalate metabolites (r between 0.26 and 039; p < 0.01). Shared sources of exposure to BPA and phthalates, such as food packaging, were suggested to be responsible for this positive correlation. Different determinants of exposure were evaluated in relation to the urinary concentrations of these chemicals. For BPA, a significant association was observed with household income class, smoking and exposure to environmental tobacco smoke. For phthalates, the following significant associations were observed: age (MBzP), educational level of the adolescent (MBzP), equivalent household income (MnBP), use of personal care products (MnBP and MBzP), wall paper in house (MnBP and MBzP) and use of local vegetables (MnBP and MBzP). (C) 2014 Elsevier Inc. All rights reserved. | Notes: | [Geens, Tinne; Covaci, Adrian] Univ Antwerp, Toxicol Ctr, B-2610 Antwerp, Antwerp, Belgium. [Bruckers, Liesbeth] Hasselt Univ, Interuniv Inst Biostat & Stat Bioinformat, Diepenbeek, Belgium. [Schoeters, Greet; Fierens, Tine; Den Hond, Elly] Flemish Inst Technol Res VITO, Environm Risk & Hlth Unit, Mol, Belgium. [Schoeters, Greet] Univ Antwerp, Dept Biomed Sci, B-2610 Antwerp, Antwerp, Belgium. [Fierens, Tine; Sioen, Isabelle] Univ Ghent, Dept Publ Hlth, B-9000 Ghent, Belgium. [Vanermen, Guido] Flemish Inst Technol Res VITO, Environm Anal & Technol Unit, Mol, Belgium. [Baeyens, Willy] Vrije Univ Brussel, Dept Analyt & Environm Chem, Brussels, Belgium. [Morrens, Bert; Loots, Ilse] Univ Antwerp, Dept Sociol, B-2610 Antwerp, Antwerp, Belgium. [Nelen, Vera] Prov Inst Hyg, Antwerp, Belgium. [de Bellevaux, Benoit Nemery] Univ Leuven, Dept Publ Hlth Occupat & Environm Med, Louvain, Belgium. [Van Larebeke, Nik] Vrije Univ Brussel, Dept Analyt & Environm Chem, Brussels, Belgium. [Van Larebeke, Nik] Univ Ghent, Study Ctr Carcinogenesis & Primary Prevent Canc, B-9000 Ghent, Belgium. | Keywords: | bisphenol-A; phthalate metabolites; biomonitoring; determinants of exposure; adolescents; Flanders;Bisphenol-A; Phthalate metabolites; Biomonitoring; Determinants of exposure; Adolescents; Flanders | Document URI: | http://hdl.handle.net/1942/18301 | ISSN: | 0013-9351 | e-ISSN: | 1096-0953 | DOI: | 10.1016/j.envres.2014.07.020 | ISI #: | 000346817100016 | Rights: | © 2014 Elsevier Inc. All rights reserved. | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2016 |
Appears in Collections: | Research publications |
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