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DC Field | Value | Language |
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dc.contributor.author | Weltens, R. | - |
dc.contributor.author | DEPREZ, Karolien | - |
dc.contributor.author | MICHIELS, Luc | - |
dc.date.accessioned | 2015-02-09T11:51:00Z | - |
dc.date.available | 2015-02-09T11:51:00Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | WASTE MANAGEMENT, 34 (12), p. 2427-2433 | - |
dc.identifier.issn | 0956-053X | - |
dc.identifier.uri | http://hdl.handle.net/1942/18302 | - |
dc.description.abstract | The Waste Framework Directive (WFD; 2008/98/EG) describes how waste materials are to be classified as hazardous or not. For complex waste materials chemical analyses are often not conclusive and the WFD provides the possibility to assess the hazardous properties by testing on the waste materials directly. As a methodology WFD refers to the protocols described in the CLP regulation (regulation on Classification, Labeling and Packaging of chemicals) but the toxicity tests on mammals are not acceptable for waste materials. The DISCRISET project was initiated to investigate the suitability of alternative toxicity tests that are already in use in pharmaceutical applications, for the toxicological hazard assessment of complex waste materials. Results indicated that Microtox was a good candidate as a first screening test in a tiered approached hazard assessment. This is now further validated in the present study. The toxic responses measured in Microtox were compared to biological responses in other bioassays for both organic and inorganic fractions of the wastes. Both fractions contribute to the toxic load of waste samples. Results show that the Microtox test is indeed a good and practical screening tool for the organic fraction. A screening threshold (ST) of 5 geq/l as the ECK, value in Microtox is proposed as this ST allows to recognize highly toxic samples in the screening test. The data presented here show that the Microtox toxicity response at this ST is not only predictive for acute toxicity in other organisms but also for sub lethal toxic effects of the organic fraction. This limit value has to be further validated. For the inorganic fraction no specific biotest can be recommended as a screening test, but the use of direct toxicity assessment is also preferable for this fraction as metal speciation is an important issue to define the toxic load of elutriate fractions. A battery of 3 tests (Microtox, Daphnia and Algae) for direct toxicity assessment of this fraction is recommended in literature, but including tests for mechanistic toxicity might be useful. (C) 2014 Elsevier Ltd. All rights reserved. | - |
dc.description.sponsorship | This project was sponsored by MIP (environmental and energy innovation platform of Flanders), by industrial partners (TACK, Shanks, Hach Lange, MicroLAN, BDS (Biodetection Systems), Labotics, Maia Scientific, Epsilon Biotech) and by OVAM, the Flemish Waste Agency. The technical support by Jef Maes, Guy Geukens, Francis Boonen, Griet Jacobs, Ab Borburg, Kelly Gyesbreghs, Karen Voortmans, Jo Van Balen, Kathleen van Loy, Julie Bukenberghs and Lien Vennekens is highly appreciated. Karolien Deprez was supported by the Belgian Research Fund (B0F07N02). | - |
dc.language.iso | en | - |
dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
dc.rights | © 2014 Elsevier Ltd. All rights reserved. | - |
dc.subject.other | microtox; hazard assessment; waste classification; biotest; toxicity screening | - |
dc.subject.other | Microtox; Hazard assessment; Waste classification; Biotest; Toxicity screening | - |
dc.title | Validation of Microtox as a first screening tool for waste classification | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 2433 | - |
dc.identifier.issue | 12 | - |
dc.identifier.spage | 2427 | - |
dc.identifier.volume | 34 | - |
local.format.pages | 7 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | [Weltens, R.] VITO, Flemish Inst Technol Res, B-2400 Mol, Belgium. [Deprez, K.; Michiels, L.] UH Hasselt Univ, BIOMED, B-3500 Hasselt, Belgium. | - |
local.publisher.place | OXFORD | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1016/j.wasman.2014.08.001 | - |
dc.identifier.isi | 000347019700002 | - |
item.validation | ecoom 2016 | - |
item.contributor | Weltens, R. | - |
item.contributor | DEPREZ, Karolien | - |
item.contributor | MICHIELS, Luc | - |
item.accessRights | Restricted Access | - |
item.fullcitation | Weltens, R.; DEPREZ, Karolien & MICHIELS, Luc (2014) Validation of Microtox as a first screening tool for waste classification. In: WASTE MANAGEMENT, 34 (12), p. 2427-2433. | - |
item.fulltext | With Fulltext | - |
crisitem.journal.issn | 0956-053X | - |
crisitem.journal.eissn | 1879-2456 | - |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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weltens 1.pdf Restricted Access | Published version | 1.16 MB | Adobe PDF | View/Open Request a copy |
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