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http://hdl.handle.net/1942/18624
Title: | The acute cardiorenal syndrome: Burden and mechanisms of disease | Authors: | NIJST, Petra MULLENS, Wilfried |
Issue Date: | 2014 | Source: | Current heart failure reports, 11 (4), p. 453-462 | Abstract: | Worsening renal function during the treatment of acute decompensated heart failure, so-called acute cardiorenal syndrome, is very common and complicates the treatment course. The underlying pathophysiology of worsening renal function (WRF) involves variable contributions of renal hemodynamics, neurohormonal activity, and oxidative stress. Historically, WRF has been associated with adverse outcomes. However, emerging data support therapeutic strategies that permit WRF while effectively treating congestion as they are associated with improved outcomes. | Keywords: | cardiorenal syndrome; worsening renal function; renal dysfunction; heart failure; congestion; central venous pressure; intraabdominal pressure; renal blood flow; renal perfusion | Document URI: | http://hdl.handle.net/1942/18624 | ISSN: | 1546-9530 | e-ISSN: | 1546-9549 | DOI: | 10.1007/s11897-014-0218-4 | Rights: | © Springer Science+Business Media New York 2014 | Category: | A3 | Type: | Journal Contribution |
Appears in Collections: | Research publications |
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