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http://hdl.handle.net/1942/18904| Title: | INTEGRATION OF HEAT-TRANSFER RESISTANCE MEASUREMENTS ONTO A DIGITAL MICROFLUIDIC PLATFORM TOWARDS THE MINIATURIZED AND AUTOMATED LABEL-FREE DETECTION OF BIOMOLECULAR INTERACTIONS | Authors: | Perez-Ruiz, Elena VANDENRYT, Thijs Witters, Daan Decrop, Deborah VAN GRINSVEN, Bart Spasic, Dragana WAGNER, Patrick Lammertyn, Jeroen |
Issue Date: | 2014 | Publisher: | IEEE | Source: | 2014 IEEE 27TH INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS), p. 272-275 | Abstract: | In this paper the successful integration of heat-transfer resistance measurements with a digital microfluidic chip is shown. The integrated miniaturized platform allows the automated label-free detection of biomolecular interactions. To immobilize biomolecules on the hydrophobic chip surface, hydrophilic gold sensing patches are created by means of a recently described dry lift-off technique that leaves the chip surface unaffected. DNA melting analysis was performed for validating the integrated device. | Notes: | [Perez-Ruiz, Elena; Witters, Daan; Decrop, Deborah; Spasic, Dragana; Lammertyn, Jeroen] KU Leuven Univ Leuven, Leuven, Belgium. [Vandenryt, Thijs; van Grinsven, Bart; Wagner, Patrick] Hasselt Univ, IMO IMOMEC, Diepenbeek, Belgium. | Document URI: | http://hdl.handle.net/1942/18904 | ISBN: | 978-1-4799-3508-6 | ISI #: | 000352217500071 | Category: | C1 | Type: | Proceedings Paper | Validations: | ecoom 2016 |
| Appears in Collections: | Research publications |
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