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http://hdl.handle.net/1942/19130
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DC Field | Value | Language |
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dc.contributor.author | Broeder, S. | - |
dc.contributor.author | Nackaerts, E. | - |
dc.contributor.author | HEREMANS, Elke | - |
dc.contributor.author | Vervoort, G. | - |
dc.contributor.author | MEESEN, Raf | - |
dc.contributor.author | Verheyden, G. | - |
dc.contributor.author | Nieuwboer, A. | - |
dc.date.accessioned | 2015-09-11T06:46:18Z | - |
dc.date.available | 2015-09-11T06:46:18Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | Neuroscience and biobehavioral reviews, 57, p. 105-117 | - |
dc.identifier.issn | 0149-7634 | - |
dc.identifier.uri | http://hdl.handle.net/1942/19130 | - |
dc.description.abstract | Recent research has highlighted the potential of transcranial direct current stimulation (tDCS) to complement rehabilitation effects in the elderly and in patients with neurological diseases, including Parkinson’s disease (PD). TDCS can modulate cortical excitability and enhance neurophysiological mechanisms that compensate for impaired learning in PD. The objective of this systematic review is to provide an overview of the effects of tDCS on neurophysiological and behavioral outcome measures in PD patients, both as a stand-alone and as an adjunctive therapy. We systematically reviewed the literature published throughout the last 10 years. Ten studies were included, most of which were sham controlled. Results confirmed that tDCS applied to the motor cortex had significant results on motor function and to a lesser extent on cognitive tests. However, the physiological mechanism underlying the long-term effects of tDCS on cortical excitability in the PD brain are still unclear and need to be clarified in order to apply this technique optimally to a wider population in the different disease stages and with different medication profiles. | - |
dc.description.sponsorship | AcknowledgementsThis work was supported by grants from the King BaudouinFoundation (Malou Malou and Amélie Fund), the Promobilia Foun-dation, the KU Leuven (project OT/11/091) and by the ResearchFoundation—Flanders (FWO) (project G.0906.11). E. Nackaerts isa Research Assistant and E. Heremans a Postdoctoral Researcher atthe Research Foundation—Flanders (FWO). | - |
dc.language.iso | en | - |
dc.rights | © 2015 Elsevier Ltd. All rights reserved. | - |
dc.subject.other | transcranial direct current stimulation; Parkinson’s disease; neuroplasticity | - |
dc.title | Transcranial direct current stimulation in Parkinson's disease: Neurophysiological mechanisms and behavioral effects. | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 117 | - |
dc.identifier.spage | 105 | - |
dc.identifier.volume | 57 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Corresponding author. Tel.: +32 16 37 21 86. E-mail addresses: sanne.broeder@faber.kuleuven.be (S. Broeder), evelien.nackaerts@faber.kuleuven.be (E. Nackaerts), elke.heremans@faber.kuleuven.be (E. Heremans), griet.vervoort@faber.kuleuven.be (G. Vervoort), raf.meesen@uhasselt.be (R. Meesen), geert.verheyden@faber.kuleuven.be (G. Verheyden), alice.nieuwboer@faber.kuleuven.be (A. Nieuwboer). | - |
local.type.refereed | Refereed | - |
local.type.specified | Review | - |
dc.identifier.doi | 10.1016/j.neubiorev.2015.08.010 | - |
dc.identifier.isi | 000364271200007 | - |
dc.identifier.url | http://www.ncbi.nlm.nih.gov/pubmed/26297812 | - |
item.fulltext | With Fulltext | - |
item.contributor | Broeder, S. | - |
item.contributor | Nackaerts, E. | - |
item.contributor | HEREMANS, Elke | - |
item.contributor | Vervoort, G. | - |
item.contributor | MEESEN, Raf | - |
item.contributor | Verheyden, G. | - |
item.contributor | Nieuwboer, A. | - |
item.accessRights | Restricted Access | - |
item.fullcitation | Broeder, S.; Nackaerts, E.; HEREMANS, Elke; Vervoort, G.; MEESEN, Raf; Verheyden, G. & Nieuwboer, A. (2015) Transcranial direct current stimulation in Parkinson's disease: Neurophysiological mechanisms and behavioral effects.. In: Neuroscience and biobehavioral reviews, 57, p. 105-117. | - |
item.validation | ecoom 2016 | - |
crisitem.journal.issn | 0149-7634 | - |
crisitem.journal.eissn | 1873-7528 | - |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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Broeder et al (2015)_Published Full Text.pdf Restricted Access | Published version | 1 MB | Adobe PDF | View/Open Request a copy |
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