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http://hdl.handle.net/1942/20103
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DC Field | Value | Language |
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dc.contributor.author | Poulatsidou, K.N. | - |
dc.contributor.author | Lagoudaki, R. | - |
dc.contributor.author | Touloumi, O. | - |
dc.contributor.author | Kesidou, E. | - |
dc.contributor.author | Boziki, M. | - |
dc.contributor.author | RAVANIDIS, Stelios | - |
dc.contributor.author | Chlichlia, K. | - |
dc.contributor.author | Grigoriou, M. | - |
dc.contributor.author | Grigoriadis, N. | - |
dc.date.accessioned | 2015-12-22T14:51:54Z | - |
dc.date.available | 2015-12-22T14:51:54Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | NEUROSCIENCE LETTERS, 611, p. 33-39 | - |
dc.identifier.issn | 0304-3940 | - |
dc.identifier.uri | http://hdl.handle.net/1942/20103 | - |
dc.description.abstract | Postnatally isolated neural precursor cells (piNPCs) from mouse cerebral tissue have been studied in cell-based therapeutic approaches for Experimental Autoimmune Encephalomyelitis (EAE). Transplantation experiments in EAE rodents revealed that piNPCs manage to integrate into the host tissue and ameliorate clinical symptoms. When cultured in vitro, mouse cerebral piNPCs form neurospheres consisting of immature cells positive for polysialylated neural adhesion molecule (PSA-NCAM) that differentiate mainly towards glial cells, but also neurons. Herein, we have characterized piNPCs immunophenotype, with flow cytometry. NPCs were positive for CD24, CD44, and CD133 though negative for CD15, CD184 and CD49d. This immunophenotype, determined for the first time, among cells isolated from neonates might be useful for the identification of NPC population aiming at the development of transplantation protocols. | - |
dc.description.sponsorship | This research has been co-financed by the European Union (European Social Fund-ESF) and Greek national funds through the Operational Program "Education and Lifelong Learning" of the National Strategic Reference Framework (NSRF)-Research Funding Program: Heracleitus II. Investing in knowledge society through the European Social Fund. We thank Dr. E Kanata and Prof. T. Sklaviadis, Pharmacy department of A.U.TH. for kindly providing N2a cell line. | - |
dc.language.iso | en | - |
dc.rights | © 2015 Published by Elsevier Ireland Ltd. | - |
dc.subject.other | mouse neural precursor cells; CD molecules; flow cytometry; polysialylated neural adhesion molecule | - |
dc.title | Immunophenotype of Mouse Cerebral Hemispheres-derived Neural Precursor Cells | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 39 | - |
dc.identifier.spage | 33 | - |
dc.identifier.volume | 611 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Grigoriadis, N (reprint author), Aristotle Univ Thessaloniki, AHEPA Univ Hosp, Dept Neurol B, Lab Expt Neurol & Neuroimmunol, Thessaloniki 54636, Greece. grigoria@med.auth.gr | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1016/j.neulet.2015.11.011 | - |
dc.identifier.isi | 000368952000006 | - |
item.accessRights | Restricted Access | - |
item.fulltext | With Fulltext | - |
item.fullcitation | Poulatsidou, K.N.; Lagoudaki, R.; Touloumi, O.; Kesidou, E.; Boziki, M.; RAVANIDIS, Stelios; Chlichlia, K.; Grigoriou, M. & Grigoriadis, N. (2015) Immunophenotype of Mouse Cerebral Hemispheres-derived Neural Precursor Cells. In: NEUROSCIENCE LETTERS, 611, p. 33-39. | - |
item.contributor | Poulatsidou, K.N. | - |
item.contributor | Lagoudaki, R. | - |
item.contributor | Touloumi, O. | - |
item.contributor | Kesidou, E. | - |
item.contributor | Boziki, M. | - |
item.contributor | RAVANIDIS, Stelios | - |
item.contributor | Chlichlia, K. | - |
item.contributor | Grigoriou, M. | - |
item.contributor | Grigoriadis, N. | - |
item.validation | ecoom 2017 | - |
crisitem.journal.issn | 0304-3940 | - |
crisitem.journal.eissn | 1872-7972 | - |
Appears in Collections: | Research publications |
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1-s2.0-S0304394015302482-main.pdf Restricted Access | Published version | 2.24 MB | Adobe PDF | View/Open Request a copy |
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