Impedance based biosensor platform design and applications

Abstract

The constant evolution of biological sensors has given a boost to the development of new E-health applications. Glucose sensors, blood and pregnancy tests all use a biological recognition element to detect a physiological change. However the readout of these biomimetic layers still needs some research. One of the methods suited for this readout is Electrochemical Impedance Spectroscopy. This powerful, non-invasive measurement technique is a well- established method in the field of biological research. Although impedance analyzers are readily available, a combination of high cost, large form factor and lack of a user-friendly operating method makes them unsuited for home use or smart device integration. This work tries to give a complete overview of the steps necessary to develop an impedance based system usable in bio-analytical measurements.