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Title: Tenckhoff tunneled peritoneal catheter placement in the palliative treatment of malignant ascites: technical results and overall clinical outcome
Authors: Maleux, Geert
Indesteege, Inge
Laenen, Annouschka 
Verslype, Chris
Vergote, Ignace
Prenen, Hans
Issue Date: 2016
Source: RADIOLOGY AND ONCOLOGY, 50 (2), p. 197-203
Abstract: Background. To assess the technical and clinical outcome of percutaneous insertion of tunneled peritoneal catheters in the palliative treatment of refractory malignant ascites and to determine the safety and feasibility of intraperitoneal administration of cytotoxic drugs through the tunneled catheter. Materials and methods. Consecutive patients palliatively treated with a tunneled peritoneal catheter to drain the malignant ascites were identified. Patients' medical history, procedural and clinical follow-up data, including complications and estimated survival, were reviewed. Additionally, a sub analysis of the patients with widespread ovarian cancer and refractory ascites treated with or without intraperitoneal administration of cytotoxic drugs was made. Results. In all 94 patients it was technically feasible to insert the peritoneal drainage catheter and to drain a median of 3260 cc (range 100 cc - 8500 cc) of malignant ascitic fluid. Post procedural complications included catheter infection (n = 2; 2%), fluid leakage around the entry site (n = 4; 4%), catheter occlusion (n = 2; 2%), sleeve formation around the catheter tip (n = 1; 1%) and accidental loss of the catheter (n = 1; 1%). There was no increase in catheter infection rate in patients treated with or without intraperitoneal administration of cytotoxic drugs. Median overall survival after catheter insertion is 1.7 months. Conclusions. Percutaneous insertion of a tunneled Tenckhoff catheter for the palliative drainage of malignant ascites and intraperitoneal infusion of cytotoxic drugs is feasible and associated with a very low complication rate, including catheter infection. These tunneled peritoneal lines are beneficial for symptomatic palliative treatment of refractory ascites and allow safe intraperitoneal chemotherapy.
Notes: [Maleux, Geert; Indesteege, Inge] Univ Hosp Leuven, Dept Radiol, Herestr 49, B-3000 Leuven, Belgium. [Laenen, Annouschka] Katholieke Univ Leuven, Dept Biostat & & Stat Bioinformat, Leuven, Belgium. [Laenen, Annouschka] Univ Hasselt, Hasselt, Belgium. [Verslype, Chris; Prenen, Hans] Univ Hosp Leuven, Dept Digest Oncol, Leuven, Belgium. [Vergote, Ignace] Univ Hosp Leuven, Dept Gynaecol, Leuven, Belgium.
Keywords: peritoneal catheter; malignant ascites; palliation;peritoneal catheter; malignant ascites; palliation
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ISSN: 1318-2099
e-ISSN: 1581-3207
DOI: 10.1515/raon-2016-0002
ISI #: 000375134500009
Category: A1
Type: Journal Contribution
Validations: ecoom 2017
Appears in Collections:Research publications

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