Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/22712
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Bedini, Andrea | - |
dc.contributor.author | De Maria, Nicola | - |
dc.contributor.author | Del Buono, Mariagrazia | - |
dc.contributor.author | Bianchini, Marcello | - |
dc.contributor.author | Mancini, Mauro | - |
dc.contributor.author | Binda, Cecilia | - |
dc.contributor.author | Brasacchio, Andrea | - |
dc.contributor.author | Orlando, Gabriella | - |
dc.contributor.author | Franceschini, Erica | - |
dc.contributor.author | Meschiari, Marianna | - |
dc.contributor.author | Sartini, Alessandro | - |
dc.contributor.author | Zona, Stefano | - |
dc.contributor.author | Paioli, Serena | - |
dc.contributor.author | Villa, Erica | - |
dc.contributor.author | GYSSENS, Inge | - |
dc.contributor.author | Mussini, Cristina | - |
dc.date.accessioned | 2016-11-23T09:01:27Z | - |
dc.date.available | 2016-11-23T09:01:27Z | - |
dc.date.issued | 2016 | - |
dc.identifier.citation | DIGESTIVE AND LIVER DISEASE, 48(10), p. 1142-1147 | - |
dc.identifier.issn | 1590-8658 | - |
dc.identifier.uri | http://hdl.handle.net/1942/22712 | - |
dc.description.abstract | Background: A major cause of the increase in antimicrobial resistance is the inappropriate use of antimicrobials. Aims: To evaluate the impact on antimicrobial consumption and clinical outcome of an antimicrobial stewardship program in an Italian Gastroenterology Department. Methods: Between October 2014 and September 2015 (period B), a specialist in infectious diseases (ID) controlled all antimicrobial prescriptions and decided about the therapy in agreement with gastroenterologists. The defined daily doses of antimicrobials (DDDs), incidence of MDR-infections, mean length of stay and overall in-hospital mortality rate were compared with those of the same period in the previous 12-months (period A). Results: During period B, the ID specialist performed 304 consultations: antimicrobials were continued in 44.4% of the cases, discontinued in 13.8%, not recommended in 12.1%, de-escalated 9.9%, escalated in 7.9%, and started in 4.0%. Comparing the 2 periods, we observed a decreased of antibiotics consumption (from 109.81 to 78.45 DDDs/100 patient-days, p = 0.0005), antifungals (from 41.28 to 24.75 DDDs/100pd, p = 0.0004), carbapenems (from 15.99 to 6.80 DDDsx100pd, p = 0.0032), quinolones (from 35.79 to 17.82 DDDsx100pd, p = 0.0079). No differences were observed in incidence of MDR-infections, length of hospital stay (LOS), and mortality rate. Conclusions: ASP program had a positive impact on reducing the consumption of antimicrobials, without an increase in LOS and mortality. | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.rights | (C) 2016 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved. | - |
dc.subject.other | Antifungals; Antimicrobial stewardship; Carbapenems; Gastroenterology; MDR-microorganisms | - |
dc.subject.other | antifungals; antimicrobial stewardship; carbapenems; gastroenterology; MDR-microorganisms | - |
dc.title | Antimicrobial stewardship in a Gastroenterology Department: Impact on antimicrobial consumption, antimicrobial resistance and clinical outcome | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 1147 | - |
dc.identifier.issue | 10 | - |
dc.identifier.spage | 1142 | - |
dc.identifier.volume | 48 | - |
local.format.pages | 6 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | [Bedini, Andrea; Brasacchio, Andrea; Orlando, Gabriella; Franceschini, Erica; Meschiari, Marianna; Zona, Stefano; Mussini, Cristina] Policlin Modena, Azienda Osped Univ, Clin Infect Dis, Modena, Italy. [De Maria, Nicola; Del Buono, Mariagrazia; Bianchini, Marcello; Binda, Cecilia; Sartini, Alessandro; Villa, Erica] Policlin Modena, Azienda Osped Univ, Gastroenterol Unit, Modena, Italy. [Mancini, Mauro; Paioli, Serena] Policlin Modena, Azienda Osped Univ, Dept Pharmaceut, Modena, Italy. [Gyssens, Inge C.] Hasselt Univ, Dept Infect Dis, Hasselt, Belgium. | - |
local.publisher.place | NEW YORK | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1016/j.dld.2016.06.023 | - |
dc.identifier.isi | 000384017800006 | - |
item.accessRights | Open Access | - |
item.contributor | Bedini, Andrea | - |
item.contributor | De Maria, Nicola | - |
item.contributor | Del Buono, Mariagrazia | - |
item.contributor | Bianchini, Marcello | - |
item.contributor | Mancini, Mauro | - |
item.contributor | Binda, Cecilia | - |
item.contributor | Brasacchio, Andrea | - |
item.contributor | Orlando, Gabriella | - |
item.contributor | Franceschini, Erica | - |
item.contributor | Meschiari, Marianna | - |
item.contributor | Sartini, Alessandro | - |
item.contributor | Zona, Stefano | - |
item.contributor | Paioli, Serena | - |
item.contributor | Villa, Erica | - |
item.contributor | GYSSENS, Inge | - |
item.contributor | Mussini, Cristina | - |
item.fulltext | With Fulltext | - |
item.fullcitation | Bedini, Andrea; De Maria, Nicola; Del Buono, Mariagrazia; Bianchini, Marcello; Mancini, Mauro; Binda, Cecilia; Brasacchio, Andrea; Orlando, Gabriella; Franceschini, Erica; Meschiari, Marianna; Sartini, Alessandro; Zona, Stefano; Paioli, Serena; Villa, Erica; GYSSENS, Inge & Mussini, Cristina (2016) Antimicrobial stewardship in a Gastroenterology Department: Impact on antimicrobial consumption, antimicrobial resistance and clinical outcome. In: DIGESTIVE AND LIVER DISEASE, 48(10), p. 1142-1147. | - |
item.validation | ecoom 2017 | - |
crisitem.journal.issn | 1590-8658 | - |
crisitem.journal.eissn | 1878-3562 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
bedini 1.pdf Restricted Access | Published version | 624.56 kB | Adobe PDF | View/Open Request a copy |
antimicrobial.pdf | Peer-reviewed author version | 371.78 kB | Adobe PDF | View/Open |
SCOPUSTM
Citations
3
checked on Sep 3, 2020
WEB OF SCIENCETM
Citations
7
checked on Apr 14, 2024
Page view(s)
50
checked on Sep 6, 2022
Download(s)
156
checked on Sep 6, 2022
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.