Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/23037
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dc.contributor.authorKaddumukasa, Mark-
dc.contributor.authorMUGENYI, Levicatus-
dc.contributor.authorKaddumukasa, Martin N.-
dc.contributor.authorDdumba, Edward-
dc.contributor.authorDevereaux, Michael-
dc.contributor.authorFurlan, Anthony-
dc.contributor.authorSajatovic, Martha-
dc.contributor.authorKatabira, Elly-
dc.date.accessioned2017-01-26T13:13:12Z-
dc.date.available2017-01-26T13:13:12Z-
dc.date.issued2016-
dc.identifier.citationBMC NEUROLOGY, 16 (Art N° 227)-
dc.identifier.issn1471-2377-
dc.identifier.urihttp://hdl.handle.net/1942/23037-
dc.description.abstractBackground: The burden of neurological diseases is increasing in developing countries. However, there is a prominent scarcity of literature on the incidence of neurological diseases in sub-Saharan Africa. This study was therefore undertaken to determine the prevalence and incidence of neurological diseases in this setting to serve as a baseline for planning and care for neurological disorders in Uganda. Methods: The study was conducted within rural and urban Mukono district, east of Kampala city of Uganda, central region. Over a period of six months, a cross sectional survey was conducted and screening was performed using a standardized questionnaire. All subjects with neurological symptoms and signs were reviewed by a team of neurologists and neurological diagnoses made. Results: Of the 3000 study subjects, 50.3% (1510/3000) were from the rural setting. Out of the participants screened, 67.4% were female, with a median age of 33 years. Among the 98 subjects with confirmed neurological disorders, the frequency of diseases was as follows; peripheral neuropathy (46.2%), chronic headaches (26.4%), and epilepsy (8.5%), followed by pain syndromes (7.5%), stroke (6.6%) and tremors/Parkinson disease (3.8%). The crude prevalence rates of these disorders (95% CI) were 14.3% (8.5-24.1); 13.3% (7.7-22.8); 33.7% (23.9-47.4) for stroke, epilepsy and peripheral neuropathy respectively. Peripheral neuropathy followed by chronic headaches had the highest estimated incidence/1000 years. Stroke had an estimated incidence of 3.6 new cases with 95% CI of (2.1-6.1)/1000 years. Conclusion: Peripheral neuropathy, chronic headaches and epilepsy disorders are major causes of morbidity in Sub-Saharan settings. There is an urgent need of more robust and powered studies to determine the incidence of these diseases.-
dc.description.sponsorshipThis study was supported by the National Institute of Neurological Disorders and Stroke of the National Institute of Health under MEPI - Neurology linked award number R25NS080968. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.-
dc.language.isoen-
dc.publisherBIOMED CENTRAL LTD-
dc.rights© The Author(s). 2016 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.-
dc.subject.otherEpidemiology; Neurological disorders; Prevalence; Uganda-
dc.subject.otherepidemiology; neurological disorders; prevalence, Uganda-
dc.titlePrevalence and incidence of neurological disorders among adult Ugandans in rural and urban Mukono district; a cross-sectional study-
dc.typeJournal Contribution-
dc.identifier.volume16-
local.format.pages9-
local.bibliographicCitation.jcatA1-
dc.description.notes[Kaddumukasa, Mark; Kaddumukasa, Martin N.; Katabira, Elly] Makerere Univ, Coll Hlth Sci, Sch Med, Dept Med, POB 7072, Kampala, Uganda. [Mugenyi, Leviticus] Infect Dis Res Collaborat, Mulago Hill Rd,MUJHU3 Bldg,POB 7475, Kampala, Uganda. [Mugenyi, Leviticus] Hasselt Univ, Interuniv Inst Biostat & Stat Bioinformat, Diepenbeek, Belgium. [Ddumba, Edward] Nkozi Univ, St Raphael St Francis Nsambya Hosp, Dept Med, POB 7146, Kampala, Uganda. [Devereaux, Michael; Furlan, Anthony] Case Western Reserve Univ, Univ Hosp Case Med Ctr, Neurol Inst, 11100 Euclid Ave, Cleveland, OH 44106 USA. [Sajatovic, Martha] Univ Hosp Case Med Ctr, Neurol & Behav Outcomes Ctr, 11100 Euclid Ave, Cleveland, OH 44106 USA.-
local.publisher.placeLONDON-
local.type.refereedRefereed-
local.type.specifiedArticle-
local.bibliographicCitation.artnr227-
dc.identifier.doi10.1186/s12883-016-0732-y-
dc.identifier.isi000388129600005-
item.validationecoom 2017-
item.contributorKaddumukasa, Mark-
item.contributorMUGENYI, Levicatus-
item.contributorKaddumukasa, Martin N.-
item.contributorDdumba, Edward-
item.contributorDevereaux, Michael-
item.contributorFurlan, Anthony-
item.contributorSajatovic, Martha-
item.contributorKatabira, Elly-
item.fulltextWith Fulltext-
item.accessRightsOpen Access-
item.fullcitationKaddumukasa, Mark; MUGENYI, Levicatus; Kaddumukasa, Martin N.; Ddumba, Edward; Devereaux, Michael; Furlan, Anthony; Sajatovic, Martha & Katabira, Elly (2016) Prevalence and incidence of neurological disorders among adult Ugandans in rural and urban Mukono district; a cross-sectional study. In: BMC NEUROLOGY, 16 (Art N° 227).-
crisitem.journal.eissn1471-2377-
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