Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/23275
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | SCHONFELD, Lisa | - |
dc.contributor.author | Jahanshahi, Ali | - |
dc.contributor.author | LEMMENS, Evi | - |
dc.contributor.author | Schipper, Sandra | - |
dc.contributor.author | DOOLEY, Dearbhaile | - |
dc.contributor.author | Joosten, Elbert | - |
dc.contributor.author | Temel, Yasin | - |
dc.contributor.author | HENDRIX, Sven | - |
dc.date.accessioned | 2017-03-02T10:01:45Z | - |
dc.date.available | 2017-03-02T10:01:45Z | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | JOURNAL OF NEUROTRAUMA, 34(2), p. 505-516 | - |
dc.identifier.issn | 0897-7151 | - |
dc.identifier.uri | http://hdl.handle.net/1942/23275 | - |
dc.description.abstract | Animal models with constant, long-lasting motor deficits together with the right tests to assess behavioral abnormalities are needed to study the effectiveness of potential therapies to restore motor functions. In the current study, controlled cortical impact (CCI) was applied in rats to induce damage to the forelimb area of the motor cortex and the dorsal striatum. Motor behavior was assessed before and after CCI, using fine motor skill tests such as the adhesive removal test, the cylinder test, and the Montoya staircase test as well as the automated gait analysis system CatWalk XT over a 6 week period. CCI caused a variety of unilateral motor deficits, which were characterized in detail by using the selected fine motor skill tests. In striking contrast to previous studies on CCI in mice, neither forelimb impairments, nor general changes in gait, were detected with the CatWalk XT. These data suggest that the adhesive removal test, the cylinder test, and the Montoya staircase test are the methods of choice to detect long-term unilateral motor deficits in rats after CCI, whereas the use of automated gait analysis systems might not be suitable to measure these behavioral deviations. | - |
dc.description.sponsorship | This work was supported in part by a grant from Hasselt University (BOF11603BOFMO) to S.H. and a grant from the Hersenstichting Nederland to Y.T. | - |
dc.language.iso | en | - |
dc.publisher | MARY ANN LIEBERT, INC | - |
dc.subject.other | adult brain injury; behavioral assessments; CCI; locomotor function; traumatic brain injury | - |
dc.subject.other | adult brain injury; behavioral assessments; CCI; locomotor function; traumatic brain injury | - |
dc.title | Long-Term Motor Deficits after Controlled Cortical Impact in Rats Can Be Detected by Fine Motor Skill Tests but Not by Automated Gait Analysis | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 516 | - |
dc.identifier.issue | 2 | - |
dc.identifier.spage | 505 | - |
dc.identifier.volume | 34 | - |
local.format.pages | 12 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | [Schonfeld, Lisa-Maria; Lemmens, Evi; Dooley, Dearbhaile; Hendrix, Sven] Hasselt Univ, Biomed Res Inst BIOMED, Dept Morphol, Hasselt, Belgium. [Schonfeld, Lisa-Maria; Jahanshahi, Ali; Schipper, Sandra; Temel, Yasin] Maastricht Univ, Dept Neurosci, Maastricht, Netherlands. [Schipper, Sandra] Maastricht Univ, Med Ctr, Dept Neurol, Maastricht, Netherlands. [Dooley, Dearbhaile] Maastricht Univ, Med Ctr, Dept Anesthesiol & Pain Management, Maastricht, Netherlands. [Jahanshahi, Ali; Temel, Yasin] Maastricht Univ, Med Ctr, Dept Neurosurg, Maastricht, Netherlands. | - |
local.publisher.place | NEW ROCHELLE | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1089/neu.2016.4440 | - |
dc.identifier.isi | 000391754800026 | - |
item.fullcitation | SCHONFELD, Lisa; Jahanshahi, Ali; LEMMENS, Evi; Schipper, Sandra; DOOLEY, Dearbhaile; Joosten, Elbert; Temel, Yasin & HENDRIX, Sven (2017) Long-Term Motor Deficits after Controlled Cortical Impact in Rats Can Be Detected by Fine Motor Skill Tests but Not by Automated Gait Analysis. In: JOURNAL OF NEUROTRAUMA, 34(2), p. 505-516. | - |
item.contributor | SCHONFELD, Lisa | - |
item.contributor | Jahanshahi, Ali | - |
item.contributor | LEMMENS, Evi | - |
item.contributor | Schipper, Sandra | - |
item.contributor | DOOLEY, Dearbhaile | - |
item.contributor | Joosten, Elbert | - |
item.contributor | Temel, Yasin | - |
item.contributor | HENDRIX, Sven | - |
item.validation | ecoom 2018 | - |
item.accessRights | Open Access | - |
item.fulltext | With Fulltext | - |
crisitem.journal.issn | 0897-7151 | - |
crisitem.journal.eissn | 1557-9042 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
schnfeld2016.pdf | Peer-reviewed author version | 2.09 MB | Adobe PDF | View/Open |
Schönfeld.Fig 1_revised.tif | Supplementary material | 1.82 MB | TIFF | View/Open |
Schönfeld.Fig 2.tif | Supplementary material | 5.06 MB | TIFF | View/Open |
Schönfeld.Fig 3.1.tif | Supplementary material | 6.89 MB | TIFF | View/Open |
Schönfeld.Fig 4.tif | Supplementary material | 4.32 MB | TIFF | View/Open |
Schönfeld.Fig 3.2.tif | Supplementary material | 6.57 MB | TIFF | View/Open |
Schönfeld.Fig 5.tif | Supplementary material | 6.37 MB | TIFF | View/Open |
Schönfeld.Fig 6.tif | Supplementary material | 2.04 MB | TIFF | View/Open |
legende.pdf | Supplementary material | 220.39 kB | Adobe PDF | View/Open |
conform.pdf Restricted Access | Published version | 1.57 MB | Adobe PDF | View/Open Request a copy |
SCOPUSTM
Citations
7
checked on Sep 5, 2020
WEB OF SCIENCETM
Citations
15
checked on Apr 30, 2024
Page view(s)
70
checked on Sep 7, 2022
Download(s)
352
checked on Sep 7, 2022
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.