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http://hdl.handle.net/1942/2334
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Garnero, P | - |
dc.contributor.author | GEUSENS, Piet | - |
dc.contributor.author | Landewe, R | - |
dc.date.accessioned | 2007-11-13T16:06:45Z | - |
dc.date.available | 2007-11-13T16:06:45Z | - |
dc.date.issued | 2003 | - |
dc.identifier.citation | CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 21(5). p. S54-S58 | - |
dc.identifier.issn | 0392-856X | - |
dc.identifier.uri | http://hdl.handle.net/1942/2334 | - |
dc.description.abstract | The progression of rheumatoid arthritis (RA), a disease characterized by synovitis, cartilage degradation and bone erosion, is highly variable from patient to patient. New specific biological markers reflecting quantitative and dynamic changes in joint tissue turnover have been recently developed and include assays for type II collagen synthesis and degradation and synovitis. Increasing evidence from prospective studies in early RA indicate that some of these markers may be useful to predict the progression and identify patients at risk for rapid joint damage, before any damage is detected by radiography. Although studies on their value in assessing the efficacy of treatments are still limited, preliminary data in early RA suggest that biological markers will play an important role in the development and the early monitoring of disease modifying antirheumatic drugs with respect to future radiographic progression. | - |
dc.language.iso | en | - |
dc.publisher | CLINICAL & EXPER RHEUMATOLOGY | - |
dc.subject.other | Early RA; cartilage; bone; synovium; type II collagen | - |
dc.title | Biochemical markers of joint tissue turnover in early rheumatoid arthritis | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | S58 | - |
dc.identifier.issue | 5 | - |
dc.identifier.spage | S54 | - |
dc.identifier.volume | 21 | - |
local.format.pages | 5 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Synarc, Mol Markers, F-69003 Lyon, France. State Univ Limburg Hosp, NL-6201 BX Maastricht, Netherlands. Univ Diepenbeek, Dr Willems Inst, Diepenbeek, Belgium.Garnero, P, Synarc, Mol Markers, 16 Rue Montbrillant, F-69003 Lyon, France. | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.bibliographicCitation.oldjcat | A1 | - |
dc.identifier.isi | 000185970100010 | - |
item.fullcitation | Garnero, P; GEUSENS, Piet & Landewe, R (2003) Biochemical markers of joint tissue turnover in early rheumatoid arthritis. In: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 21(5). p. S54-S58. | - |
item.accessRights | Closed Access | - |
item.contributor | Garnero, P | - |
item.contributor | GEUSENS, Piet | - |
item.contributor | Landewe, R | - |
item.fulltext | No Fulltext | - |
item.validation | ecoom 2004 | - |
crisitem.journal.issn | 0392-856X | - |
crisitem.journal.eissn | 1593-098X | - |
Appears in Collections: | Research publications |
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