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http://hdl.handle.net/1942/23618
Title: | Drugs, doses, and durations of intraperitoneal chemotherapy: standardizing HIPEC and EPIC for colorectal, appendiceal, gastric, ovarian peritoneal surface malignancies and peritoneal mesothelioma. | Authors: | LEMOINE, Lieselotte Sugarbaker, Paul VAN DER SPEETEN, Kurt |
Issue Date: | 2017 | Source: | INTERNATIONAL JOURNAL OF HYPERTHERMIA, 33 (5), p. 582-592 | Status: | In Press | Abstract: | Peritoneal surface malignancy (PSM) is a common manifestation of digestive and gynecologic malignancies alike. At present, patients with isolated PSM are treated with a combination therapy of cytoreductive surgery (CRS) and hyperthermic peroperative intraperitoneal chemotherapy (HIPEC). The combination of CRS and intraperitoneal (IP) chemotherapy should now be considered standard of care for PSM from appendiceal epithelial cancers, colorectal cancer and peritoneal mesothelioma. Although there is a near universal standardization regarding the CRS, we are still lacking a much-needed standardization amongst the various IP chemotherapy treatment modalities used today in clinical practice. Pharmacologic evidence should be generated to answer important questions raised by the myriad of variables associated with IP chemotherapy. | Notes: | Van der Speeten, K (reprint author), Ziekenhuis Oost Limburg, Dept Surg Oncol, Schiepse Bos 6, B-3600 Genk, Belgium kurt.vanderspeeten@zol.be | Keywords: | peritoneal surface malignancy; HIPEC; EPIC; BIC | Document URI: | http://hdl.handle.net/1942/23618 | ISSN: | 0265-6736 | e-ISSN: | 1464-5157 | DOI: | 10.1080/02656736.2017.1291999 | ISI #: | 000404780700014 | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2018 |
Appears in Collections: | Research publications |
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Drugs doses and durations of intraperitoneal chemotherapy standardizing HIPEC and EPIC for colorectal appendiceal gastric ovarian peritoneal surface.pdf | Peer-reviewed author version | 1.11 MB | Adobe PDF | View/Open |
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