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http://hdl.handle.net/1942/23656
Title: | Influence of continuously evolving transcatheter aortic valve implantation technology on cerebral oxygenation. | Authors: | EERTMANS, Ward GENBRUGGE, Cornelia Fret, Tom Beran, Maud Engelen, Kim GUTERMANN, Herbert VANDER LAENEN, Margot BOER, Willem Ferdinande, Bert JANS, Frank DENS, Jo DE DEYNE, Cathy |
Issue Date: | 2016 | Source: | JOURNAL OF CLINICAL MONITORING AND COMPUTING, 31 (6), p. 1133-1141 | Status: | In press | Abstract: | This study assessed the influence of the evolution in Transcatheter Aortic Valve Implantation technology on cerebral oxygenation. Cerebral oxygenation was measured continuously with Near-Infrared Spectroscopy and compared retrospectively between balloon-expandable, self-expandable and differential deployment valves which were implanted in 12 (34%), 17 (49%) and 6 patients (17%), respectively. Left and right SctO2 values were averaged at four time points and used for analysis (i.e. at baseline, balloon-aortic valvuloplasty, valve deployment, and at the end of the procedure). During balloon-aortic valvuloplasty and valve deployment, cerebral oxygenation decreased in patients treated with balloon or self-expandable valves (balloon-expandable: p = 0.003 and p = 0.002; self-expandable: p < 0.001 and p = 0.003, respectively). The incidence of cerebral desaturations below 80% of baseline was significantly larger in patients treated with balloon-expandable valves (p = 0.001). In contrast, patients who received differential deployment valves never experienced a cerebral desaturation below 80% of baseline. Furthermore, both the incidence and duration below a cerebral oxygenation of 55% was significantly different between balloon and self-expandable valves (p = 0.038 and p = 0.018, respectively). This study demonstrated that Transcatheter Aortic Valve Implantation procedures are associated with significant cerebral desaturations, especially during balloon-aortic valvuloplasty and valve deployment. Moreover, our results showed that latest innovations in Transcatheter Aortic Valve Implantation technology beneficially influenced the adequacy of cerebral perfusion. | Notes: | Eertmans, W (reprint author), Ziekenhuis Oost Limburg Genk, Dept Anaesthesiol Intens Care Emergency Med & Pai, Schiepse Bos 6, B-3600 Genk, Belgium. ward.eertmans@uhasselt.be | Keywords: | Transcatheter Aortic Valve Implantation; near-infrared spectroscopy; rapid ventricular pacing; evolution in valve technology | Document URI: | http://hdl.handle.net/1942/23656 | Link to publication/dataset: | The final publication is available at https://link.springer.com/article/10.1007/s10877-016-9971-0 | ISSN: | 1387-1307 | e-ISSN: | 1573-2614 | DOI: | 10.1007/s10877-016-9971-0 | ISI #: | 000413761000004 | Rights: | © Springer Science+Business Media Dordrecht 2016 | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2018 |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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First print_TAVI paper.pdf Restricted Access | Published version | 999.96 kB | Adobe PDF | View/Open Request a copy |
Eertmans_Influence of continuously evolving transcatheter aortic valve implantation technology on cerebral oxygenation.pdf | Peer-reviewed author version | 285.31 kB | Adobe PDF | View/Open |
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