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http://hdl.handle.net/1942/23939| Title: | Teri-DYNAMIC: Exploring the impact of teriflunomide on immune cell population size, receptor repertoire, and function in patients with RRMS | Authors: | Wiendl, Heinz Gross, Catharina C. Eschborn, Melanie Weisser, Linda Posevitz-Fejfar, Anita Schulte-Mecklenbeck, Andreas VAN WIJMEERSCH, Bart Hupperts, Raymond Brette, Sandrine Turner, Timothy J. Bar-Or, Amit Klotz, Luisa |
Issue Date: | 2017 | Publisher: | SAGE PUBLICATIONS LTD | Source: | MULTIPLE SCLEROSIS JOURNAL, 23(1), p. 144-144 (Art N° 69) | Abstract: | Teriflunomide, an immunomodulator approved for patients with relapsing forms of MS, specifically inhibits proliferation of activated lymphocytes. Teri-DYNAMIC (NCT01863888) characterized the immunomodulatory effects of teriflunomide treatment on lymphocyte subsets in patients with relapsing–remitting multiple sclerosis (RRMS). Objectives: To explore the immunomodulatory effects of teriflunomide on lymphocyte subsets, receptor repertoire, and function in patients with RRMS. | Notes: | [Wiendl, H.; Gross, C. C.; Eschborn, M.; Weisser, L.; Fejfar, A. Posevitz; Mecklenbeck, A. Schulte; Klotz, L.] Univ Munster, Munster, Germany. [Van Wijmeersch, B.] Hasselt Univ, Hasselt, Belgium. [Hupperts, R.] Maastricht Univ, Med Ctr, Orbis Med Ctr, Maastricht, Netherlands. [Brette, S.] Lincoln, Boulogne, France. [Turner, T. J.] Sanofi Genzyme, Cambridge, MA USA. [Bar-Or, A.] McGill Univ, Montreal Neurol Inst, Montreal, PQ, Canada. | Document URI: | http://hdl.handle.net/1942/23939 | ISSN: | 1352-4585 | e-ISSN: | 1477-0970 | DOI: | 10.1177/1352458516666193 | ISI #: | 000393906000059 | Category: | M | Type: | Journal Contribution |
| Appears in Collections: | Research publications |
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| 10.1177@1352458516666193.pdf Restricted Access | Published version | 640.14 kB | Adobe PDF | View/Open Request a copy |
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